Isobromotopsentin: a New Bis(indole) Alkaloid From a Deep-Water Marine Sponge Spongosorites sp.

1995 ◽  
Vol 48 (12) ◽  
pp. 2053 ◽  
Author(s):  
LM Murray ◽  
TK Lim ◽  
JNA Hooper ◽  
RJ Capon

Isobromotopsentin (16) is a new brominated bis(indole) alkaloid isolated from a deep-water marine sponge Spongosorites sp. collected off the southern Australian coast. The structure for (16) was determined by spectroscopic methods.

ChemInform ◽  
2010 ◽  
Vol 27 (18) ◽  
pp. no-no
Author(s):  
L. M. MURRAY ◽  
T. K. LIM ◽  
J. N. A. HOOPER ◽  
R. J. CAPON

1988 ◽  
Vol 53 (13) ◽  
pp. 3116-3118 ◽  
Author(s):  
Shigeo Kohmoto ◽  
Yoel Kashman ◽  
Oliver J. McConnell ◽  
Kenneth L. Rinehart ◽  
Amy Wright ◽  
...  

1992 ◽  
Vol 57 (17) ◽  
pp. 4772-4775 ◽  
Author(s):  
Amy E. Wright ◽  
Shirley A. Pomponi ◽  
Sue S. Cross ◽  
Peter McCarthy

ChemInform ◽  
1988 ◽  
Vol 19 (51) ◽  
Author(s):  
S. KOHMOTO ◽  
Y. KASHMAN ◽  
O. J. MCCONNELL ◽  
K. L. JUN. RINEHART ◽  
A. WRIGHT ◽  
...  

Marine Drugs ◽  
2018 ◽  
Vol 16 (12) ◽  
pp. 474 ◽  
Author(s):  
Wirongrong Kaweetripob ◽  
Chulabhorn Mahidol ◽  
Pittaya Tuntiwachwuttikul ◽  
Somsak Ruchirawat ◽  
Hunsa Prawat

Four sesterterpenes, erectusolides B, C, D, and seco-manoalide-25-methyl ether, two 2-furanone derivatives, erectusfuranones A and B, together with thirteen known sesterterpenes, (6Z)-neomanoalide-24-acetate, two diastereomers of 24-O-methylmanoalide, luffariolide B, manoalide, (6E)- and (6Z)-neomanoalide, seco-manoalide, scalarafuran, 12-acetylscalarolide, 12-epi-O-deacetyl-19-deoxyscalarin, 12-epi-scalarin, and 12-O-deacetyl-12-epi-scalarin, three indole alkaloids, 5-hydroxy-1H-indole-3-carbaldehyde, hyrtiosine A, and variabine B, and one norterpene, cavernosine were isolated from the marine sponge Hyrtios erectus. Their structures were determined by means of spectroscopic methods and the absolute configurations of the asymmetric centers were determined using the modified Mosher’s method. The cytotoxic activities for the isolated compounds have been reported.


2006 ◽  
Vol 61 (7-8) ◽  
pp. 472-476 ◽  
Author(s):  
Maria Augusta Medeiros ◽  
Ana Lourenço ◽  
Maria Regina Tavares ◽  
Maria João Marcelo Curto ◽  
Sónia Savluchinske Feio ◽  
...  

(-)-Agelasidine A was identified from the methanol extract of the marine sponge Agelas clathrodes for the first time together with zooanemonin, 1-carboxymethylnicotinic acid, hymenidin, mukanadins A and C, monobromodispacamide, agelasidine D, 2-amide-4-bromopyrrole, O-methyltryptophan and an agelasines mixture. The structures were characterized by spectroscopic methods. (-)-Agelasidine A was tested for antibacterial and antifungal activities and shown to act as a bacteriostatic agent as it inhibited the growth of Staphylococcus aureus and partially the growth of other bacteria.


1990 ◽  
Vol 43 (11) ◽  
pp. 1861 ◽  
Author(s):  
TW Hambley ◽  
A Poiner ◽  
WC Taylor

From the deep violet, encrusting marine sponge Chelonaplysilla violacea, two rearranged spongian diterpenes, aplyviolene, (1R*,1′S*,3?aR*,5R*,6R*,8R*,8′aS*)-3-oxo-8-(1′,4′,4′-trimethyl-8′-methylenedecahydroazulen-1′-yl)-2,7-dioxabicyclo[3.2.1]oct-6-yl acetate (1), the acetoxy derivative, aplyviolacene (2), (5R*,8S*,9S*,10R*,13S*,14R* ,15S*,16R*)-spongian-15,16-diyl diacetate (3) and (5R*,8S*,9S*,10R*,13S*,14R*)-spongian-16-one (4) were isolated. The structures were determined by spectroscopic methods, and the structure of aplyviolene was confirmed by a single-crystal X-ray determination. The crystal structure was refined to a residual of 0.036 for 1125 independent observed reflections. The crystals were orthorhombic, space group P212121 with a 8.098(1), b 11.628(1), c 21.774(3)Ǻ.


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