Intramolecular Oxidative Coupling of Aromatic Compounds. VI. An Efficient Synthesis of Some Dibenzocyclooctene Lignans

1994 ◽  
Vol 47 (5) ◽  
pp. 937 ◽  
Author(s):  
AR Carroll ◽  
WC Taylor
Keyword(s):  
Trans Isomer ◽  
Trifluoroacetic Acid ◽  
Aromatic Compounds ◽  
Oxidative Coupling ◽  
Good Yield ◽  
Reductive Coupling ◽  
Efficient Synthesis

The 1,4-diaryl-2,3-dimethylbutanes (4) and (5) were readily prepared by reductive coupling of an arylacetone precursor followed by hydrogenation. Intramolecular oxidative coupling (dichlorodicyanobenzoquinone/trifluoroacetic acid) gave dibenzocyclooctene derivatives in good yield. (�)-Deoxyschizandrin and the corresponding trans isomer, existing in two distinct conformations, were prepared.

Intramolecular Oxidative Coupling of Aromatic Compounds. VII. A Convenient Synthesis of (±)-Deoxyschizandrin

1994 ◽  
Vol 47 (8) ◽  
pp. 1579 ◽  
Author(s):  
AR Carroll ◽  
RW Read ◽  
WC Taylor
Keyword(s):  
Aromatic Compounds ◽  
Oxidative Coupling ◽  
Claisen Rearrangement ◽  
Oxidative Cleavage ◽  
Reductive Coupling ◽  
Convenient Synthesis

A convenient synthesis of (�)-deoxyschizandrin was achieved through the key step of reductive coupling of the bisacetonylbiphenyl (3). The latter compound was synthesized by oxidative cleavage of the bis olefin (5) formed by Claisen rearrangement of the bismethallyl ether of 2,2′,4,4′-tetramethoxybiphenyl-3,3′-diol. The synthesis of 2,2′,4,4′-tetramethoxy-6,6′-di(prop 1-enyl)biphenyl-3,3′-diol (2) is also described. The diphenolic oxidation of (2) did not lead to products with β,β′ carbons linked.

Efficient Synthesis of DiAZT Triphosphate

2014 ◽  
Vol 662 ◽  
pp. 59-62
Author(s):  
Shan Shan Gong ◽  
Qi Sun
Keyword(s):  
Efficient Method ◽  
Good Yield ◽  
Efficient Synthesis

A facile and efficient method for the synthesis ofP1,P3-dizidovudine-5′,5′-triphosphate has been developed. The coupling of zidovudine diphosphate with zidovudine phosphoropiperidate based on the DCI activation of P-N bond afforded the desired product in good yield.

Eine effiziente Synthesemethode für DiarylallenyIiden(pentacarbonyl)chrom- und -wolfram-Komplexe -Kristallstruktur von (CO)5Cr=C=C=CPh2 / An efficient Synthesis of Diarylallenylidene Pentacarbonyl Chromium and Tungsten Complexes - Crystal Structure of (CO)5Cr=C=C=CPh2

1994 ◽  
Vol 49 (9) ◽  
pp. 1207-1214 ◽  
Author(s):  
Helmut Fischer ◽  
David Reindl ◽  
Gerhard Roth
Keyword(s):  
Crystal Structure ◽  
Structure Analysis ◽  
Good Yield ◽  
Efficient Synthesis ◽  
X Ray ◽  
Tungsten Complexes ◽  
And Tungsten

An efficient synthesis of diarylallenylidene pentacarbonyl chromium and tungsten com­plexes is presented. Irradiation of M(CO)6 in THF affords (CO)sM[THF], Substitution of the THF ligand by diarylpropargylalcoholate and subsequent desoxygenation with COCF gives the title compounds in good yield. (The structure of diphenylallenylidene pentacarbonyl chromium has been determined by X-ray structure analysis

Efficient synthesis of 2,3-dimethoxy-5-methyl-6-morpholinomethyl-1,4-benzoquinone hydrochloride

2015 ◽  
Vol 70 (4) ◽  
pp. 221-223 ◽  
Author(s):  
Jin Wang ◽  
Teng-huo-sheng Liao ◽  
Jian Yang
Keyword(s):  
Title Compound ◽  
Good Yield ◽  
Efficient Synthesis ◽  
Reaction Sequence

AbstractThe title compound (5) was prepared by a reaction sequence starting from 2,3,4,5-tetramethoxytoluene (1) via the Blanc reaction, oxidation and alkylation. The described method provides a good yield of the C-6 heterocyclic-substituted benzoquinone derivative and is suitable for the synthesis of other benzoquinone derivatives.

Efficient Synthesis of Thiophene-Based Polycyclic Aromatic Compounds

Synfacts ◽  
2006 ◽  
Vol 2006 (5) ◽  
pp. 0445-0445 ◽  
Author(s):  
J. Pei ◽  
W.-Y. Zheng ◽  
J. Mao ◽  
X.-H. Zhou
Keyword(s):  
Aromatic Compounds ◽  
Polycyclic Aromatic Compounds ◽  
Efficient Synthesis ◽  
Polycyclic Aromatic
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