Solubilization of pada in Hydrocarbon Fluorocarbon Surfactant Mixtures

1992 ◽  
Vol 45 (4) ◽  
pp. 769 ◽  
Author(s):  
TJ Connolly ◽  
VC Reinsborough ◽  
XY Xiang
Keyword(s):  
Mixed Micelle ◽  
Mixed Micelles ◽  
Surfactant Mixtures ◽  
Critical Micelle Concentrations ◽  
Fluorocarbon Surfactant ◽  
Surfactant Systems ◽  
Sodium Decyl Sulfate ◽  
Sodium Perfluorooctanoate

Solubilities of pyridine-2-azo-p-dimethylaniline ( pada ) were determined at 25�C in four mixed fluorocarbon/hydrocarbon short-chained surfactant systems: ( i ) sodium decyl sulfate/sodium perfluoroheptanoate; (ii) sodium octanesulfonate /sodium perfluorooctanoate ; (iii) sodium octanesulfonate /sodium perfluoroheptanoate ; (iv) sodium nonanesulfonate /sodium perfluoroheptanoate. Systems ( i ), (iii) and (iv) showed micellar miscibility (one mixed micelle) and synergistic solubilization effects. System (ii) had two critical micelle concentrations pointing to two micellar forms in solution, and no synergism could be detected. From these four examples, it is deduced that single mixed micelles are formed when the critical micelle concentrations of the pure surfactants are within a factor of 3 of each other.

scholarly journals Mixed Micelle and Mixed Adsorbed Film Formations of Anionic Fluorocarbon-Nonionic Hydrocarbon Surfactant Mixtures Sodium Perfluorooctanoate with MEGA-8, 9 and 10

1990 ◽  
Vol 39 (8) ◽  
pp. 548-554 ◽  
Author(s):  
Yutaka WADA ◽  
Yoshitomi IKAWA ◽  
Hirotsune IGIMI ◽  
Yoshio MURATA ◽  
Shigemi NAGADOME ◽  
...  
Keyword(s):  
Mixed Micelle ◽  
Surfactant Mixtures ◽  
Adsorbed Film ◽  
Sodium Perfluorooctanoate

scholarly journals Detailed Calorimetric Analysis of Mixed Micelle Formation from Aqueous Binary Surfactants for Design of Nanoscale Drug Carriers

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3288
Author(s):  
Ádám Juhász ◽  
László Seres ◽  
Norbert Varga ◽  
Ditta Ungor ◽  
Marek Wojnicki ◽  
...  
Keyword(s):  
Mixed Micelle ◽  
Mixed Micelles ◽  
Drug Carrier ◽  
Micelle Formation ◽  
Water Soluble ◽  
Titration Calorimetry ◽  
Surfactant Mixtures ◽  
Calorimetric Analysis ◽  
Mixed Micelle Formation ◽  
Ideal Mixing

While numerous papers have been published according to the binary surfactant mixtures, only a few articles provide deeper information on the composition dependence of the micellization, and even less work attempts to apply the enhanced feature of the mixed micelles. The most important parameter of the self-assembled surfactants is the critical micelle concentration (cmc), which quantifies the tendency to associate, and provides the Gibbs energy of micellization. Several techniques are known for determining the cmc, but the isothermal titration calorimetry (ITC) can be used to measure both cmc and enthalpy change (ΔmicH) accompanying micelle formation. Outcomes of our calorimetric investigations were evaluated using a self-developed routine for handling ITC data and the thermodynamic parameters of mixed micelle formation were obtained from the nonlinear modelling of temperature- and composition- dependent enthalpograms. In the investigated temperature and micelle mole fractions interval, we observed some intervals where the cmc is lower than the ideal mixing model predicted value. These equimolar binary surfactant mixtures showed higher solubilization ability for poorly water-soluble model drugs than their individual compounds. Thus, the rapid and fairly accurate calorimetric analysis of mixed micelles can lead to the successful design of a nanoscale drug carrier.

Thermodynamic Study on the Miscibility of Sodium Perfluorooctanoate and Sodium Decyl Sulfate in the Adsorbed Film and Micelle

1995 ◽  
Vol 174 (1) ◽  
pp. 156-161 ◽  
Author(s):  
Makoto Aratono ◽  
Masaaki Ikeguchi ◽  
Takanori Takiue ◽  
Norihiro Ikeda ◽  
Kinsi Motomura
Keyword(s):  
Thermodynamic Study ◽  
Adsorbed Film ◽  
Sodium Decyl Sulfate ◽  
Sodium Perfluorooctanoate

scholarly journals Molecular Interactions in Binary Surfactant Solutions: Effect of pH

2019 ◽  
Vol 64 (4) ◽  
pp. 437-445
Author(s):  
Olga Kochkodan ◽  
Victor Maksin ◽  
Nadiya Antraptseva ◽  
Tetyana Semenenko
Keyword(s):  
Molecular Interactions ◽  
Mixed Micelles ◽  
Ph Value ◽  
Chemical Properties ◽  
Micelle Formation ◽  
Bulk Solution ◽  
Surfactant Mixtures ◽  
Solution Ph ◽  
Solution Interface ◽  
Adsorption Layers

By using surface tension and conductivity measurements, the colloid-chemical properties of the mixtures of cationic hexadecylpyridinium bromide with nonionic Triton X-100 surfactants were investigated both in the bulk solution and at air/solution interface at different pH values. The composition of mixed micelles and adsorption layers, parameters of molecular interactions in mixed micelles βm and adsorption layers βσ, as well as standard free energies of micelle formation ΔG0mic and adsorption ΔG0ads were calculated. It was found that molecules of the nonionic surfactant presumably dominate in the mixed micelles and adsorption layers. It was shown that βm and βσ have negative values, which indicate the strengthening of intermolecular interactions in the mixed micelles and adsorption layers. Based on the data obtained, it was suggested that ion-dipole interactions are involved in the formation of intermolecular structures between nonionic and cationic surfactants in aqueous solution and at the air-solution interface. It was shown that βm, βσ as well as ΔG0mic and ΔG0ads parameter depends on the solution pH value. The complex interplay of ion-dipole, protonation and chelation processes, which occur in the surfactant mixtures at different pH and affect the strength of intermolecular interaction, should be taken into account for data analysis.

scholarly journals Solution inclusion complexes of cyclodextrins with sodium perfluorooctanoate

1989 ◽  
Vol 67 (10) ◽  
pp. 1550-1553 ◽  
Author(s):  
Ramamurthy Palepu ◽  
Vincent C. Reinsborough
Keyword(s):  
Inclusion Complex ◽  
Inclusion Complexes ◽  
Goodness Of Fit ◽  
Sodium Ion ◽  
The Other ◽  
Cyclodextrin Complexes ◽  
Fluorocarbon Surfactant ◽  
Other Hand ◽  
Fluorocarbon Chain ◽  
Sodium Perfluorooctanoate

Pre-micellar and micellar sodium perfluorooctanoate solutions (SPFO) were examined conductometrically with added α-cyclodextrin(α-CD), β-cyclodextrin (β-CD), and γ-cyclodextrin (γ-CD). The order of stability of the 1:1 inclusion complex was (β-CD > γ-CD > α-CD determined largely by the goodness of fit of the fluorocarbon chain in the CD cavity. Sodium ion electrode studies revealed that some Na+ ion is associated with the (β-CD/SPFO complex. As shown by fluorine-19 nmr, (β-CD girds the SPFO molecule snugly amidship with the terminal CF3 group still in solution. On the other hand, SPFO manages only a weak penetration of the fluorocarbon chain into the smaller α-CD cavity. Keywords: perflurooctanoate, cyclodextrin complexes, fluorocarbon surfactant, 19F nmr.

Phase behavior of polymer-surfactant systems in relation to polymer-polymer and surfactant-surfactant mixtures

1993 ◽  
Vol 65 (5) ◽  
pp. 953-958 ◽  
Author(s):  
B. Lindman ◽  
Ali Khan ◽  
E. Marques ◽  
M. Graca da Miguel ◽  
L. Piculell ◽  
...  
Keyword(s):  
Phase Behavior ◽  
Surfactant Mixtures ◽  
Surfactant Systems ◽  
Polymer Surfactant

Influence of taurocholate, taurochenodeoxycholate, and taurodehydrocholate on sulfobromophthalein transport into bile.

1979 ◽  
Vol 236 (1) ◽  
pp. E10
Author(s):  
S Binet ◽  
Y Delage ◽  
S Erlinger
Keyword(s):  
Bile Salts ◽  
Mixed Micelle ◽  
Mixed Micelles ◽  
Important Determinant ◽  
Micelle Formation ◽  
Similar Increase ◽  
Mixed Micelle Formation ◽  
Series Of Experiments

To test the hypothesis that incorporation of sulfobromophthalein (BSP) into mixed micelles could account for the increase in its biliary transport maximum (Tmax) by bile salts, we have compared in hamsters the influence on BSP Tmax of taurocholate and taurochenodeoxycholate (two micelle-forming physiological bile salts) to that of taurodehydrocholate, a bile salt which, in vitro, does not form micelles. In a first series of experiments, it was observed that taurocholate and taurochenodeoxycholate increased the secretion of phospholipid (40 and 53%, respectively), and cholesterol (50 and 110%, respectively), whereas taurodehydrocholate decreased the secretion of phospholipid (-31%) and cholesterol (-43%). This result suggests that, in vivo, taurodehydrocholate or its metabolites do not form mixed micelles. In a second series of experiments, it was seen that the three bile salts induced a similar increase in BSP Tmax (63% with taurocholate, 52% with taurochenodeoxycholate, and 51% with taurodehydrocholate). These results provide circumstantial evidence for the hypothesis that mixed micelle formation is not an important determinant of maximal BSP secretion into bile.

Sign in / Sign up

Export Citation Format

Share Document