Nitrones and Oxaziridines. XXXVII. Some Oxidation Reactions of 1-Pyrroline 1-Oxides

1988 ◽  
Vol 41 (2) ◽  
pp. 183 ◽  
Author(s):  
DSC Black ◽  
RJ Strauch
Keyword(s):  
Potassium Carbonate ◽  
Anhydrous Potassium Carbonate ◽  
Selenium Dioxide ◽  
Oxidation Reactions ◽  
Similar Treatment

The 2,4-diaryl-1-pyrroline 1-oxides (4) can be converted into the related 2H-pyrrole 1-oxides (5) by treatment with N-bromosuccinimide and anhydrous potassium carbonate. Similar treatment of the 1-pyrroline 1-oxide (6) yielded the succinimido-substituted pyrroline (7). Selenium dioxide oxidation of the tetramethyl nitrone (8) under various conditions gave mixtures containing the compounds (10)-(12). Neither process provides a general conversion of 1-pyrroline 1-oxides into 2H-pyrrole 1-oxides.

Synthesis, Characterization, Antimicrobial Screening of 5-Bromobenzofuranyl Aryl Ureas and Carbamates

2019 ◽  
Vol 4 (4) ◽  
pp. 232-235
Author(s):  
H.M. Naveena Kumari ◽  
Manjunath Harihara Mathada ◽  
Mahesh Kumar ◽  
K.T. Suda ◽  
K.M. Basavaraja
Keyword(s):  
Acetic Acid ◽  
Hydrazine Hydrate ◽  
Sodium Nitrite ◽  
Potassium Carbonate ◽  
Anhydrous Potassium Carbonate ◽  
Antimicrobial Activities ◽  
Anhydrous Toluene ◽  
Ethyl Carbamate ◽  
Primary Amines ◽  
Antimicrobial Screening

Present work reports the biologically important benzofuran aryl ureas and carbamates. The benzofuran ring was formed by reacting bromo salicylaldehyde with diethyl bromomalonate in presence of dry acetone and anhydrous potassium carbonate to obtain 5-bromo-2-ethyl carboxylate (1). The obtained ester (1) was converted into corresponding hydrazide (2) by treating with hydrazine hydrate in ethanol. Compound 2 was then converted into 5-bromobenzofuran-2-carbonyl azide (3) by treating it with sodium nitrite in dioxane and acetic acid. The compound 3 is converted into 5-bromobenzofuranyl aryl ureas (4a-e) after treating primary amines and anhydrous toluene. 5-Bromobenzofuranyl aryl carbamate (5) and ethyl carbamate (6) were also synthesized by treating compound 3 with substituted phenol in toluene and ethanol respectively. All the compounds were characterized by NMR, IR and screened for antimicrobial activities.

Kinetics of the Reaction of Solid Anhydrous Potassium Carbonate with Gaseous Sulfur Dioxide

1994 ◽  
Vol 59 (11) ◽  
pp. 2357-2374 ◽  
Author(s):  
Erich Lippert ◽  
Karel Mocek ◽  
Emerich Erdös
Keyword(s):  
Sulfur Dioxide ◽  
Water Vapour ◽  
Potassium Carbonate ◽  
Anhydrous Potassium Carbonate ◽  
Heterogeneous Reaction ◽  
Fixed Bed ◽  
Partial Pressures ◽  
Flow Apparatus ◽  
Gaseous Sulfur ◽  
Kinetics Of

Results are presented of an experimental kinetic study of the heterogeneous reaction between gaseous sulfur dioxide and solid anhydrous potassium carbonate. The measurements were carried out in an all glass kinetic flow apparatus with nitrogen as the carrier gas and a fixed bed of the solid working in the differential regime at atmospheric pressure and a temperature of 423 K (150 °C). The reaction course was studied in dependence on the partial pressures of sulfur dioxide (pSO2) and water vapour (pH2O) in concentration ranges pSO2 = 13 - 430 Pa and pH2O = 0 - 2 100 Pa. In the reaction, water vapour acts as a gaseous catalyst. Based on the experimental data, the corresponding kinetic equation was found together with the numerical values of the relevant rate and equilibrium adsorption constants.

SYNTHESIS OF α-AMINO ACIDS FROM ETHYL CYANOACETATE

1952 ◽  
Vol 30 (8) ◽  
pp. 592-597 ◽  
Author(s):  
Paul E. Gagnon ◽  
Guy Nadeau ◽  
Raymond Côté
Keyword(s):  
Amino Acids ◽  
Hydrochloric Acid ◽  
Alkaline Medium ◽  
Potassium Carbonate ◽  
Ethyl Cyanoacetate ◽  
Similar Treatment ◽  
Aqueous Hydrochloric Acid ◽  
Hydrolysis Of ◽  
Curtius Degradation

Monosubstituted cyanoacetic esters, obtained by condensation of 1-bromo-3(s)-phenoxypropanes (s = o-Cl, o-Br, o-I, o-, m-, and p-NO2) or 1-bromo-2(s)-phenoxyethanes (s = o-Cl, o-Br, o-I, and m-NO2) with ethyl cyanoacetate by means of potassium carbonate, were transformed through a Curtius degradation into cyanoacetisocyanates. These compounds by hydrolysis in acid or alkaline medium gave α-amino acids. However, hydrolysis of the corresponding carbobenzyloxy- or carbethoxyaminonitriles afforded better yields. The carbobenzyloxyaminonitriles were more readily hydrolyzed in aqueous hydrochloric acid than the carbethoxyaminonitriles. Moreover, the mild action of dry hydrochloric acid on the carbobenzyloxy derivatives yielded the α-amino acids readily whereas similar treatment of the carbethoxy derivatives gave the carbethoxyamino acids.

Oxidation reactions of acetylenic fatty esters with selenium dioxide/tert-butyl hydroperoxide

Lipids ◽  
1997 ◽  
Vol 32 (10) ◽  
pp. 1119-1123 ◽  
Author(s):  
Marcel S. F. Lie Ken Jie ◽  
Mohammed Khysar Pasha ◽  
Mohammad Shahin Alam
Keyword(s):  
Selenium Dioxide ◽  
Oxidation Reactions ◽  
Fatty Esters ◽  
Butyl Hydroperoxide ◽  
Tert Butyl ◽  
Tert Butyl Hydroperoxide

5-Aminouracil as a Building Block in Heterocyclic Synthesis: Part I. One-pot Synthesis of Pyrimido[5,4-b]quinolin-2,4,9-triones under Microwave Irradiation without Catalyst

2008 ◽  
Vol 63 (12) ◽  
pp. 1431-1437 ◽  
Author(s):  
Raafat M. Shaker ◽  
Mohamed Abd Elrady
Keyword(s):  
Microwave Irradiation ◽  
Potassium Carbonate ◽  
Building Block ◽  
Anhydrous Potassium Carbonate ◽  
Nmr Spectra ◽  
Heterocyclic Synthesis ◽  
One Pot ◽  
One Pot Condensation ◽  
Elemental Analyses ◽  
C Nmr

A series of 6,7,8,10-tetrahydropyrimido[5,4-b]quinolin-2,4,9-(1H,3H,5H)-triones 6 were synthesized through one-pot condensation of 5-aminouracil, aldehydes and dimedone in DMF under microwave irradiation without catalyst. The products 6a, d were oxidized to the 7,8-dihydro-pyrimido- [5,4-b]quinolin-2,4,9-(1H,3H,6H)-triones 11a, b. Treatment of 6a, d and/or 11a, b with ethyl iodide in the presence of anhydrous potassium carbonate gave the ethylated derivatives 12a, b and 13a, b, respectively. The structures of the products were confirmed by elemental analyses, IR, MS, 1H, and 13C NMR spectra.

scholarly journals Methyl-2-Thienylketopolymethyleneoxyphenyl Derivatives of Alkyl-Substituted 4,5-Dihydro-Oxazoles with Anti-Human Picornavirus Activity

1996 ◽  
Vol 7 (4) ◽  
pp. 213-220 ◽  
Author(s):  
A. Mai ◽  
M. Artico ◽  
S. Massa ◽  
R. Ragno ◽  
A. De Montis ◽  
...  
Keyword(s):  
Potassium Carbonate ◽  
Anhydrous Potassium Carbonate ◽  
Sodium Iodide ◽  
Wide Spectrum ◽  
The Other ◽  
Triphenyl Phosphine ◽  
Spectrum Activity ◽  
Diethyl Azodicarboxylate ◽  
Derivatives Of

The synthesis of 5-methyl-2-thienylketopolymethylene oxyphenyl 4,5-dihydro-2-(alkyl)oxazoles was accomplished by the assembly of two synthones, namely 1-(5-methyl-2-thienyl)-7-hydroxy-1-heptanone (or 1-(5-methyl-2-thienyl)-5-chloro-1-pentanone) and 4-[4,5-dihydro(alkyl)oxazol-2-yl]phenol, in the presence of diethyl azodicarboxylate(DEAD)-triphenyl phosphine (or sodium iodide and anhydrous potassium carbonate). Eighteen new disoxaril analogues were synthesized by the above procedure and tested in vitro against several rhino and enteroviruses. With a few exceptions, all test derivatives were more potent than WIN 51711 when assayed against HRV-14, and as potent as WIN 51711 against HRV-2, but none of them inhibited the other HRV serotypes. Among the various derivatives, two compounds showed the same wide spectrum activity of WIN 51711 against several rhino, and enteroviruses, but were at least 10-fold less toxic.

Synthesis and Research of Properties of Polyether Ether Ketone

2019 ◽  
Vol 816 ◽  
pp. 55-60
Author(s):  
Z.I. Kurdanova ◽  
Azamat Zhansitov ◽  
Azamat L. Slonov ◽  
K.T. Shakhmurzova ◽  
A.E. Baykaziev ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Molecular Weight ◽  
High Temperature ◽  
Polymer Chain ◽  
Potassium Carbonate ◽  
Anhydrous Potassium Carbonate ◽  
Branching Processes ◽  
Polyether Ether Ketone ◽  
Ether Ketone

Polyether ether ketones based on 4,4'-difluorobenzophenone and hydroquinone in sulfolane medium in the presence of anhydrous potassium carbonate were synthesized by the method of high-temperature polycondensation. The rheological, thermal, electrical and physical-mechanical properties are investigated. It is shown that, at processing temperatures, the molecular weight of polyether ether ketones synthesized in sulfolane increases, apparently due to the branching processes of the polymer chain.

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