Carvone- and Piperitone-Derived Allylic Stannanes and Aspects of Their Electrophilic Substitution

1986 ◽  
Vol 39 (4) ◽  
pp. 563 ◽  
Author(s):  
D Young ◽  
M Jones ◽  
W Kitching
Keyword(s):  
Sulfur Dioxide ◽  
Electrophilic Substitution ◽  
Optically Active ◽  
Substitution Reactions ◽  
Cis And Trans

cis - and trans- Carvotanacetols and - piperitols have been converted into the corresponding allylic chlorides, which were made to react with both trimethyltinlithium and triphenyltinlithium . The resulting allylic stannanes were characterized by 1H, 13C and 119Sn n.m.r . spectroscopy, which permitted assignment of the relative configurations. Triphenyltinlithium appears to react in a (substantially) concerted fashion with the (optically active) chloride from the carvotanacetols yielding an optically active stannane . The corresponding trimethylstannane is optically inactive. Substitution reactions (SE′) with acid and sulfur dioxide (in chloroform) are preferentially γ-anti and specifically γ- syn respectively, in line with conclusions based on other cyclohex-2-enyl systems.

The Chemistry of Triazine Isomers: Structures, Reactions, Synthesis and Applications

2020 ◽  
Vol 20 ◽  
Author(s):  
Neelottama Kushwaha ◽  
C S Sharma
Keyword(s):  
Basic Property ◽  
Electrophilic Substitution ◽  
Antimicrobial Agents ◽  
Resonance Energy ◽  
Heterocyclic Ring ◽  
Ring System ◽  
Agricultural Fields ◽  
Substitution Reactions ◽  
Anti Cancer ◽  
Benzene Structure

: Triazine is the six-membered heterocyclic ring containing three nitrogen which replaces carbon-hydrogen unit in the benzene ring. Based on nitrogen position present in the ring system, it is categorized in three isomeric forms i.e.1, 2, 3-triazine (vicinal triazine), 1, 2, 4-triazine (asymmetrical triazine or isotriazine) and 1, 3, 5-triazine (symmetrical or s-triazine or cyanidine). Triazines have weakly basic property. Its isomers have much weaker resonance energy than benzene structure, so nucleophilic substitution reactions are more preferred than electrophilic substitution reactions. Triazine isomers and their derivatives are known to play important roles possessing various activities in medicinal and agricultural fields such as anti-cancer, antiviral, fungicidal, insecticidal, bactericidal, herbicidal, antimalarial and antimicrobial agents.

Organotellurium compounds: an overview of synthetic methodologies

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Muhammad Irfan ◽  
Rabia Rehman ◽  
Mohd. R. Razali ◽  
Muhammad Adnan Iqbal ◽  
◽  
...  
Keyword(s):  
Material Science ◽  
Electrophilic Substitution ◽  
Comprehensive Understanding ◽  
Substitution Reactions ◽  
Current Review ◽  
Synthetic Routes ◽  
Electrophilic Substitution Reactions ◽  
Synthetic Methodologies ◽  
Organotellurium Compounds

AbstractIn wake of emerging applications of organotellurium compounds in biological and material science avenues, the current review describes their key synthetic methodologies while focusing the synthesis of organotellurium compounds through five ligand-to-metal linkages including carbon; carbon-oxygen; carbon-nitrogen; carbon-metal; carbon-sulfur to tellurium. In all of these linkages whether tellurium links with ligands through a complicated or simple pathways, it is often governed through electrophilic substitution reactions. The present study encompasses these major synthetic routes so as to acquire comprehensive understanding of synthetic organotellurium compounds.

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