Chlorosulfination of Aromatic Methyl Ethers with Thionyl Chloride

1985 ◽  
Vol 38 (8) ◽  
pp. 1209 ◽  
Author(s):  
KH Bell
Keyword(s):  
Thionyl Chloride ◽  
Room Temperature ◽  
Starting Material ◽  
High Yield

Aromatic sulfinyl chlorides have been prepared in high yield by direct chlorosulfination of some aromatic ethers (1,3-dimethoxybenzene, 2- methyl- and 4-chloro-1,3-dimethoxybenzene, 1,2,3-trimethoxybenzene, 1- and 2-methoxynaphthalene, 1,5-, 1,7-, 2,6- and 2,7- dimethoxynaphthalene ) with thionyl chloride alone at or below room temperature. Under the same conditions, 1,4-dimethoxynaphthalene and 1,3-dimethoxy-5-methylbenzene yield chlorinated starting materials and sulfides. 1,3,5-Trimethoxybenzene yields chlorinated starting material, sulfide, and a chlorinated disulfide. Some other ethers (e.g. anisole, 1,2- and 1,4-dimethoxybenzene, 5-chloro-1,3-dimethoxybenzene) are unreactive under these conditions.

scholarly journals ZnO/RGO Heterojunction Based near Room Temperature Alcohol SENSOR with Improved Efficiency

2021 ◽  
Vol 6 (1) ◽  
pp. 25
Author(s):  
Sanghamitra Ghosal ◽  
Partha Bhattacharyya
Keyword(s):  
Active Sites ◽  
Room Temperature ◽  
Surface Engineering ◽  
Gas Sensing ◽  
Energy Band Diagram ◽  
Future Generation ◽  
High Yield ◽  
Synthesis Process ◽  
Ethanol Sensor ◽  
Vapor Sensing

The systematic optimization of surface engineering (dimensionality) indeed plays a crucial role in achieving efficient vapor-sensing performance. Among various semiconducting metal oxides, owing to some of its unique features and advantages, ZnO has attracted researchers on a global scale due to its application in various fields, including chemical sensors. The concomitant optimization of the surface attributes (varying different dimensions) of ZnO have become a sensation for the entire research community. Moreover, the small thickness and extremely large surface of exfoliated 2D nanosheets render the gas sensing material an ideal candidate for achieving strong coupling with different gas molecules. However, temperature is a crucial factor in the field of chemical sensing. Recently, graphene-based gas sensors have attracted attention due to their variety of structures, unique sensing performances and room temperature working conditions. In this work, a highly sensitive and fast responsive low temperature (60 °C)-based ethanol sensor, based on RGO/2D ZnO nanosheets hybrid structure, is reported. After detailed characterizations, the vapor sensing potentiality of this sensor was tested for the detection of ethanol. The ethanol sensor offered the response magnitude of 89% (100 ppm concentration) with response and recovery time of 12 s/29 s, respectively. Due to excessively high number of active sites for VOC interaction, with high yield synthesis process and appreciably high carrier mobility, this has paved the way for developing future generation, miniaturized and flexible (wearable) vapor sensor devices, meeting the multidimensional requirements for traditional and upcoming (health/medical sector) applications. The underlying mechanistic framework for vapor sensing, using this hybrid junction, is explained with the Energy Band Diagram.

Solvent effect on simple and high yield synthesis of polydichlorophosphazene precursor Cl3PNSiMe3

2021 ◽  
Author(s):  
Elif Büşra Çelebi ◽  
Ferda Hacıvelioğlu
Keyword(s):  
Solvent Effect ◽  
Room Temperature ◽  
Solvent Polarity ◽  
High Yield ◽  
Effect Of Solvent ◽  
Nonpolar Solvents

The effect of solvent polarity on the reaction of PCl5 with (Me3Si)2NH has been investigated and it is found that nonpolar solvents promote the formation of Cl3PNSiMe3, whereas the more polar chloroform gives unusual phosphazenes at room temperature.

An efficient multicomponent, one-pot synthesis of Betti bases catalyzed by cerium (IV) ammonium nitrate (CAN) at ambient temperature

2016 ◽  
Vol 5 (4) ◽  
Author(s):  
Ramadan Ahmed Mekheimer ◽  
Abdullah Mohamed Asiri ◽  
Afaf Mohamed Abdel Hameed ◽  
Reham R. Awed ◽  
Kamal Usef Sadek
Keyword(s):  
Ambient Temperature ◽  
Environmental Pollution ◽  
Ammonium Nitrate ◽  
Room Temperature ◽  
Catalytic Amount ◽  
High Yield ◽  
Reaction Conditions ◽  
One Pot ◽  
Work Up ◽  
Cerium Iv Ammonium Nitrate

AbstractStarting from readily available 2-naphthol, aldehydes, aryl and alkylamines, a variety of Betti bases were efficiently synthesized utilizing a catalytic amount of cerium (IV) ammonium nitrate (CAN) at room temperature. This protocol has advantages of high yield, mild reaction conditions, no environmental pollution, diversity of reactants and simple work up procedure.

scholarly journals Purification of cathepsin B by a new form of affinity chromatography

1986 ◽  
Vol 235 (3) ◽  
pp. 731-734 ◽  
Author(s):  
D H Rich ◽  
M A Brown ◽  
A J Barrett
Keyword(s):  
Affinity Chromatography ◽  
Cathepsin B ◽  
Single Step ◽  
Starting Material ◽  
High Yield ◽  
Cysteine Proteinases ◽  
New Form ◽  
Human Cathepsin ◽  
Sepharose 4B

Human cathepsin B was purified by affinity chromatography on the semicarbazone of Gly-Phe-glycinal linked to Sepharose 4B, with elution by 2,2′-dipyridyl disulphide at pH 4.0. The product obtained in high yield by the single step from crude starting material was 80-100% active cathepsin B. The possibility that this new form of affinity chromatography may be of general usefulness in the purification of cysteine proteinases is discussed.

Room temperature preparation of cellulose nanocrystals with high yield via a new ZnCl2 solvent system

2021 ◽  
pp. 118946
Author(s):  
Junchai Zhao ◽  
Mengwei Deng ◽  
Shuaiyao Li ◽  
Zheng Guan ◽  
Yixuan Xia ◽  
...  
Keyword(s):  
Cellulose Nanocrystals ◽  
Room Temperature ◽  
Solvent System ◽  
High Yield ◽  
Temperature Preparation

An Efficient Two-Step Protocol for the Isoprenylation of Xanthone at the C2 Position Starting from 1-Fluoroxanthone Derivative

Synlett ◽  
2020 ◽  
Vol 31 (14) ◽  
pp. 1423-1429
Author(s):  
Takashi Matsumoto ◽  
Yuuki Fujimoto ◽  
Chisato Furukawa ◽  
Kanae Takahashi ◽  
Miho Mochizuki ◽  
...  
Keyword(s):  
Silica Gel ◽  
Room Temperature ◽  
Claisen Rearrangement ◽  
High Yield ◽  
Side Chain ◽  
Snar Reaction

The SNAr reaction of 1-fluoroxanthone derivatives with alkoxide of 1,1-dimethylallyl alcohol cleanly afforded the corresponding ethers, which have thus far been unavailable. The obtained ethers underwent the Claisen rearrangement at room temperature by treatment with silica gel in toluene. This two-step protocol provides expeditious and high-yield access to xanthones possessing isoprenyl or the related allylic side chain at the C2 position.

Continuous flow biodiesel production from wet microalgae using a hybrid thin film microfluidic platform

2018 ◽  
Vol 54 (85) ◽  
pp. 12085-12088 ◽  
Author(s):  
Eko K. Sitepu ◽  
Darryl B. Jones ◽  
Youhong Tang ◽  
Sophie C. Leterme ◽  
Kirsten Heimann ◽  
...  
Keyword(s):  
Thin Film ◽  
Continuous Flow ◽  
Room Temperature ◽  
Biodiesel Production ◽  
High Yield ◽  
Hybrid Thin Film ◽  
Microfluidic Platform ◽  
Thin Film Device ◽  
Wet Microalgae

A novel continuous flow turbo-thin film device (T2FD) is effective in producing biodiesel in high yield from wet microalgae at room temperature.

Reaction of trans-2-Acylaminocyclanols with Thionyl Chloride

1971 ◽  
Vol 49 (12) ◽  
pp. 2064-2072 ◽  
Author(s):  
R. A. B. Bannard ◽  
N. C. C. Gibson ◽  
J. H. Parkkari
Keyword(s):  
Thionyl Chloride ◽  
Half Life ◽  
Spectral Characteristics ◽  
High Yield ◽  
Methyl Proton ◽  
Reaction Solution ◽  
Crude Product ◽  
Proton Resonances ◽  
General Method

trans-2-Acetamidocyclohexanol (1; n = 2, R = CH3) on addition to thionyl chloride in chloroform at 0° was converted rapidly and quantitatively to D,L-2-methyl-4,5-cis-cyclohexanoöxazoline hydrochloride (2; n = 2, R = CH3) judging from shifts in the methyl proton resonances of the n.m.r. spectra of the amide and the reaction solution. The intermediate chlorosulfinate was estimated to have a half-life of less than 2.25 min. The oxazoline salt was isolated in 98% yield by sublimation of the crude product in vacuo and was identified by its i.r. and n.m.r. spectra and by its facile and almost quantitative hydrolysis to cis-2-aminocyclohexanol hydrochloride. The oxazoline salts 2 (n = 1, R = CH3, [Formula: see text] and n = 2, R = C6H5, [Formula: see text]) were readily obtained in 95 % yield or better by the same general method and it was shown that the trans-2-acetamidocyclanols are the preferred starting materials for conversion to cis-2-aminocyclanol derivatives by the thionyl chloride inversion reaction. The oxazoline bases 4 (n = 1, R = CH3, [Formula: see text] and n = 2, R = CH3, [Formula: see text]) were readily obtained in high yield from the corresponding salts and differences in the i.r. and n.m.r. spectral characteristics of the salts and bases are reported.

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