A Phytochemical Investigation of Erythroxylon australe F. Muell

1978 ◽  
Vol 31 (5) ◽  
pp. 1161 ◽  
Author(s):  
WJ Griffin
Keyword(s):  
Gas Chromatography ◽  
Spectral Analysis ◽  
Propionic Acid ◽  
Acid Moiety ◽  
Mass Spectral Analysis ◽  
Mass Spectral ◽  
Aerial Parts ◽  
Phytochemical Investigation ◽  
Phenyl Propionic Acid

(�)-6β,7β-Dihydroxytropan-3α-yl benzoate was isolated in low yield (0.001%) from the roots of Erythroxylon australe. The aerial parts were found to contain meteloidine (0.014%), (�)-6β-hydroxytropan-3α-yl tiglate (0.001%), (+)-3α-hydroxynortropan-6β-yl tiglate (0.002%) and an unknown base (0.003%) which was tentatively identified as (+)-7- hydroxy-6-tigloyloxynortropan-3-yl 2-hydroxy-3-phenylpropionate. The configuration of the unknown base was not determined. Structures were indicated by N.M.R. and mass spectral analysis and the phenyl propionic acid moiety identified by gas chromatography.

scholarly journals Flavonoids from Stellaria nemorum and Stellaria holostea

2015 ◽  
Vol 10 (3) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Elena Ancheeva ◽  
Georgios Daletos ◽  
Rini Muharini ◽  
Wen Han Lin ◽  
Leonid Teslov ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Spectral Analysis ◽  
Acid Hydrolysis ◽  
Two Dimensional ◽  
Mass Spectral Analysis ◽  
Mass Spectral ◽  
Aerial Parts ◽  
Crude Extracts ◽  
First Time

Stellaria nemorum L. and S. holostea L. (Caryophyllaceae) were investigated for their flavonoids. The new flavonoid 6- C-[(α-arabinopyranosyl)-(1→2)- O-β-xylopyranosyl]apigenin (1) and the four known C-glycosides, 6- C-[(α-arabinopyranosyl)-(1→2)- O-β-glucopyranosyl]apigenin (2), apigenin 6- C-β-galactopyranoside-8- C-β-glucopyranoside (3), apigenin 6- C-β-glucopyranoside-8- C-α-arabinopyranoside (4), and apigenin 6- C-β-glucopyranoside-8- C-β-xylopyranoside (5) were isolated from the aerial parts of S. nemorum for the first time. Furthemore, five known flavonoids, 3,5,7-trihydroxy-3′,5′-dimethoxyflavone (9), diosmetin 6- C-β-glucopyranoside (8), schaftoside (4), isoorientin (6) and orientin (7) were obtained from the aerial parts of S. holostea. Compounds 4, 8 and 9 are reported for the first time from this species. The structures of all isolated compounds were unambiguously elucidated by one- and two- dimensional NMR and mass spectral analysis, by acid hydrolysis, as well as by comparison with literature data. The crude extracts of the investigated species exhibited antimicrobial activity against Staphylococcus aureus, while none of the isolated compounds was found to be active.

scholarly journals SYNTHESIS, CHARACTERIZATION, AND ANTHELMINTIC ACTIVITY OF NOVEL BENZOTHIAZOLE DERIVATIVES CONTAINING INDOLE MOIETIES

2019 ◽  
pp. 321-325
Author(s):  
ALETI RAJAREDDY ◽  
SRINIVAS MURTHY M
Keyword(s):  
Spectral Analysis ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Fourier Transform Infrared Spectroscopy ◽  
Anthelmintic Activity ◽  
Mass Spectral Analysis ◽  
Standard Drug ◽  
Mass Spectral ◽  
Benzothiazole Derivatives

Objective: The objective of this study was to synthesize and evaluate the anthelmintic activity (AA) of novel benzothiazole derivatives containing indole moieties (BDIM). Methods: The present works which involve the substituted isatin Schiff bases undergo acetylating and reacting with 2-aminobenzothiazole to give novel BDIM. Results: All the newly synthesized molecules (5a-5o) were characterized by Fourier-transform infrared spectroscopy, H_nuclear magnetic resonance, and mass spectral analysis along with physical data. The biological potentials of the newly synthesized compounds are evaluated for their AA using an Indian earthworm (Pheretima posthuma), and albendazole was used as standard drug. Conclusion: The synthesized compound 5f, 5n, and 5o showed good AA, whereas others exhibited significant activities.

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