Trimeric products from the free radical oxidation of (Z)-isoeugenol

1976 ◽  
Vol 29 (5) ◽  
pp. 1127 ◽  
Author(s):  
IJ Miller
Keyword(s):  
Free Radical ◽  
Magnetic Resonance ◽  
Spectral Properties ◽  
Proton Magnetic Resonance ◽  
Free Radical Oxidation ◽  
Oxidation Products ◽  
Radical Oxidation ◽  
Mass Spectral ◽  
Radical Coupling

Four trimeric oxidation products have been isolated from the reaction between isoeugenol and tri-t-butylphenoxyl radical in methanol, and structures for these have been proposed on the basis of their proton magnetic resonance and mass spectral properties. All linkages were those expected from radical coupling, and one of the products was an acetal. Thus a route to the formation of ketones in lignin is demonstrated.

scholarly journals CHARACTERISTIC OF FREE-RADICAL DAMAGE AND ANTIOXIDANT PROTECTION STATE IN PATIENTS WITH CHRONIC KIDNEY DISEASE AGAINST A BACKGROUND OF MALABSORPTION SYNDROME

2021 ◽  
Vol 20 (3) ◽  
Author(s):  
А.Е. Shkarutyak
Keyword(s):  
Chronic Kidney Disease ◽  
Free Radical ◽  
Kidney Disease ◽  
Free Radical Oxidation ◽  
Oxidation Products ◽  
Essential Factor ◽  
Free Radical Damage ◽  
Radical Oxidation ◽  
Oxidation Processes ◽  
Radical Damage

Oxidation processes play an important role in damage of the renal structures, especiallyagainst a background of other serious pathologies, in particular, malabsorptionsyndrome.The study of the mechanisms of mutual aggravation and progression of kidneydamage against a background of malabsorption is a very urgent problem of the presenttime.Purpose - to investigate the state of free radical oxidation of lipids, proteins andantioxidant defense in patients with chronic kidney disease of different ages withoxaluria against a background of malabsorption syndrome.Material and methods. 98 patients with chronic kidney disease of the I-II stages(pyelonephritis) with the presence of oxaluria against a background of malabsorptionsyndrome of different age were examined.The age of the patients under examination was32 - 64. All patients underwent a study of the system of free radical oxidation of lipidsand proteins.Results. chronic kidney disease with the presence of oxaluria is accompanied by asignificant increase in the blood content of free radical oxidation products, namelyaldehyde and ketone dinitrophenylhydrazones, especially of a neutral nature,malondialdehyde, as well as a significant decrease in the indicators of the antioxidantdefense system, which manifested itself to a greater extent in patients with older age.groups.Conclusion. An essential factor in the development and progression of chronic kidneydisease with the presence of oxaluria against a background of malabsorption syndromeis an increase in the intensity of free radical oxidation of lipids and proteins (mainly dueto aldehyde and ketondinitrophenylhydrazones of a neutral nature).

The level of free radical oxidation products in heart and blood plasma by diabetes mellitus with chronic alcohol intoxication

2010 ◽  
Vol 56 (2) ◽  
pp. 257-265
Author(s):  
A.V. Indutny ◽  
D.E. Bykov ◽  
V.E. Vysokogorsky
Keyword(s):  
Diabetes Mellitus ◽  
Free Radical ◽  
Blood Plasma ◽  
Alcohol Intoxication ◽  
Free Radical Oxidation ◽  
Oxidation Products ◽  
Chronic Alcohol ◽  
Chronic Alcohol Consumption ◽  
Radical Oxidation ◽  
Chronic Alcohol Intoxication

The research results of level glycemia, contents of free radical oxidation products (thiobarbiturate-reactive substances, oxidized-modified proteins) in blood plasma and heart of diabetes mellitus rats with chronic alcohol intoxication are presented. It is shown, that at presence of a diabetes mellitus the chronic alcohol consumption does not change blood plasma levels of the oxidized-modified proteins, thiobarbiturate-reactive substances and glucose. However the contents of thiobarbiturate-reactive substances and oxidizing modification of proteins products in animals heart is more considerably increased at combination of the diabetes with chronic alcohol consumption, in comparison with changes at the diabetes mellitus outside of alcoholization and with changes at the isolated chronic alcohol influence. Found out alcohol-induced free radical processes hyperactivation in heart at the diabetes is capable to render additional injuring influence.

scholarly journals Free-Radical Oxidation (Peroxidation) Products in Plasma in Normal and Abnormal Pregnancy

1981 ◽  
Vol 18 (3) ◽  
pp. 158-162 ◽  
Author(s):  
D Wickens ◽  
M H Wilkins ◽  
J Lunec ◽  
G Ball ◽  
T L Dormandy
Keyword(s):  
Blood Pressure ◽  
Free Radical ◽  
Radical Reaction ◽  
Free Radical Oxidation ◽  
Oxidation Products ◽  
Control Group ◽  
Free Radical Reaction ◽  
Reaction Products ◽  
Third Trimester ◽  
Radical Oxidation

Using recently developed methods for measuring free-radical oxidation products in biological material, plasma extracts were studied in 24 women in the first two trimesters of pregnancy, in 124 women in the third trimester of pregnancy, in 20 women with pre-eclamptic toxaemia (PET), and in a control group. There was a significant progressive rise of two groups of free-radical oxidation products throughout pregnancy and a significantly greater rise in PET. In women whose diastolic blood pressure rose to above 70 mmHg there was a highly significant relation between two groups of free-radical reaction products and blood pressure.

LIPID-PEROXIDATION (FREE-RADICAL-OXIDATION) PRODUCTS IN BILE FROM PATIENTS WITH PANCREATIC DISEASE

The Lancet ◽  
1983 ◽  
Vol 322 (8346) ◽  
pp. 375-379 ◽  
Author(s):  
J.M. Braganza ◽  
D.G. Wickens ◽  
P. Cawood ◽  
T.L. Dormandy
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Free Radical Oxidation ◽  
Pancreatic Disease ◽  
Oxidation Products ◽  
Radical Oxidation

scholarly journals DYNAMICS OF FREE RADICAL OXIDATION INDICES AND ANTIOXIDANT PROTECTION IN MALE RATS’ HEART UNDERGONE VARIOUS TYPES OF STRESS

2020 ◽  
pp. 41-48
Author(s):  
O. V. Denefil ◽  
S. S. Riabokon ◽  
I. R. Mits
Keyword(s):  
Free Radical ◽  
Emotional Stress ◽  
Prenatal Stress ◽  
Free Radical Oxidation ◽  
Oxidation Products ◽  
Female Rats ◽  
Male Rats ◽  
Antioxidant Protection ◽  
Radical Oxidation ◽  
Postnatal Stress

Any change of external or internal environment causes body’s responses that facilitate its adaptation. Pathogenesis of stress reaction study is always topical as it is aimed at the investigation of optimal adaptation mechanisms to impaired agents. The aim – to study the dynamics of free-radical oxidation indices and antioxidant protection in male rats’ heart undergone chronic prenatal, postnatal stress and their combination. Material and Methods. The study was performed on 44 white non-pedigreed pubertal three-month-rats. Prenatal stress was induced by keeping pregnant female rats in narrow pencil case for an hour. Postnatal stress was induced in 1.5 to three-month- rats by keeping them in cages with living space restriction twice as much. Combined stress comprised using two methods. Contents of peroxide lipids oxidation products and antioxidant protection were determined in the heart. Results. Psycho-emotional stress in three-month-rats causes activation processes of peroxide lipids oxidation and antioxidant protection regardless of stressor’s period action. On the basis of correlations study it was proved that development mechanisms of chronic stress depend on life-period when stress was sustained. Conclusions. Processes of peroxide lipids oxidation in all modelling types of stress are intensified in young male-rats’ heart during the effect of chronic psycho-emotional stress. Activity of enzyme part of antioxidant protection increases simultaneously with the increase of LPO products in the heart. It is more manifested in prenatal and postnatal stress. Intensification of glutathione system action and disturbances of its activity, especially in animals that undergone prenatal stress were also marked.

Sign in / Sign up

Export Citation Format

Share Document