Chemistry of the Podocarpaceae. XXXV. 12-Methoxypodocarpa-8,11,13- triene and 12-Methoxyabieta-8,11,13-triene derivatives: A synthesis of (+)-hinokione methyl ether
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12-Methoxypodocarpa-8,11,13-trien-19-oic acid (9) and 12-methoxyabieta- 8,11,13-trien-19-oic acid (10) have been converted into 3-0x0-4,4-dimethyl derivatives (15) and (18) by successive reactions involving oxidative decarboxylation, selective epoxidation, epoxide opening, double bond isomerization, oxidation, and reductive methylation. The sequence starting from the acid (10) provides a synthesis of the methyl ether of hinokione (14).
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1984 ◽
Vol 106
(12)
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pp. 3681-3682
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1971 ◽
pp. 150-162
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2011 ◽
Vol 51
(5)
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pp. 1270-1273
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2018 ◽
Vol 18
(1)
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pp. 439-444
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