Poly-L-alanylglycyl-L-alanylglycyl-L-serylglycine: A synthetic model of Bombyx mori Silk Fibroin

1966 ◽  
Vol 19 (3) ◽  
pp. 489 ◽  
Author(s):  
FHC Stewart

The sequential polypeptide [Ala-Gly-Ala-Gly-Ser-Gly]n has been prepared by polymerization of a hexapeptide p-nitrophenyl ester. This polymer contains the repeating sequence of amino acid residues present in the crystalline regions of Bombyx mori silk fibroin. The o-nitrophenylsulphenyl amino-protecting group was used extensively in the synthesis of the hexapeptide active monomer from which the polypeptide was obtained.

1955 ◽  
Vol 77 (14) ◽  
pp. 3908-3913 ◽  
Author(s):  
W. A. Schroeder ◽  
Lois M. Kay ◽  
Barry Lewis ◽  
Nancy Munger

2005 ◽  
Vol 6 (5) ◽  
pp. 2563-2569 ◽  
Author(s):  
Sung-Won Ha ◽  
Hanna S. Gracz ◽  
Alan E. Tonelli ◽  
Samuel M. Hudson

2017 ◽  
Vol 5 (11) ◽  
pp. 2152-2160 ◽  
Author(s):  
Tetsuo Asakura ◽  
Masanori Endo ◽  
Rina Fukuhara ◽  
Yugo Tasei

Conformational characterization of the amino acid residues in hydrated silk fibroin sponges.


Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 58
Author(s):  
Traian V. Chirila

Fibroin is a fibrous protein that can be conveniently isolated from the silk cocoons produced by the larvae of Bombyx mori silk moth. In its form as a hydrogel, Bombyx mori silk fibroin (BMSF) has been employed in a variety of biomedical applications. When used as substrates for biomaterial-cells constructs in tissue engineering, the oxygen transport characteristics of the BMSF membranes have proved so far to be adequate. However, over the past three decades the BMSF hydrogels have been proposed episodically as materials for the manufacture of contact lenses, an application that depends on substantially elevated oxygen permeability. This review will show that the literature published on the oxygen permeability of BMSF is both limited and controversial. Additionally, there is no evidence that contact lenses made from BMSF have ever reached commercialization. The existing literature is discussed critically, leading to the conclusion that BMSF hydrogels are unsuitable as materials for contact lenses, while also attempting to explain the scarcity of data regarding the oxygen permeability of BMSF. To the author’s knowledge, this review covers all publications related to the topic.


1992 ◽  
Vol 46 (1) ◽  
pp. 49-53 ◽  
Author(s):  
Tetsuo Asakura ◽  
Motohiro Kitaguchi ◽  
Makoto Demura ◽  
Harutoshi Sakai ◽  
Keiichi Komatsu

2013 ◽  
Vol 51 (9) ◽  
pp. 742-748 ◽  
Author(s):  
Mingying Yang ◽  
Wen He ◽  
Yajun Shuai ◽  
Sijia Min ◽  
Liangjun Zhu

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