Preparation and Characterization of PMMA Particles Incorporating a Chemical Sunscreen Agent for Improvement of UV Protection Ability

2018 ◽  
Vol 71 (3) ◽  
pp. 177 ◽  
Author(s):  
Suning Zhang ◽  
Wenyang Wang ◽  
Tao Chen

UV protection ability is an important concern in the application of sunscreen. Modifying well-known UV filters is one of the most important ways to develop sunscreens. In this study, poly(methyl methacrylate)–ethylhexyl salicylate (PMMA-EHS) particles were prepared via miniemulsion polymerization using a redox initiator at low temperature. Compared with free EHS, the sun protection factor (SPF) value of PMMA-EHS particles was increased by ~40 %, which indicated a significant improvement in UV protection ability from encapsulating EHS in PMMA. Prepared PMMA-EHS particles proved non-leaky in application and can greatly reduce skin irritation by preventing direct contact of EHS with skin.

2020 ◽  
Vol 21 (4) ◽  
Author(s):  
Alice Haddad do Prado ◽  
Victor Hugo Sousa Araújo ◽  
Josimar O. Eloy ◽  
Bruno Fonseca-Santos ◽  
Marcelo A. Pereira-da-Silva ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Atmaram P. Pawar ◽  
Aditya P. Gholap ◽  
Ashwin B. Kuchekar ◽  
C. Bothiraja ◽  
Ashwin J. Mali

Background. Oxybenzone, a broad spectrum sunscreen agent widely used in the form of lotion and cream, has been reported to cause skin irritation, dermatitis, and systemic absorption. Aim. The objective of the present study was to formulate oxybenzone loaded microsponge gel for enhanced sun protection factor with reduced toxicity. Material and Method. Microsponge for topical delivery of oxybenzone was successfully prepared by quasiemulsion solvent diffusion method. The effects of ethyl cellulose and dichloromethane were optimized by the 32 factorial design. The optimized microsponges were dispersed into the hydrogel and further evaluated. Results. The microsponges were spherical with pore size in the range of 0.10–0.22 µm. The optimized formulation possesses the particle size and entrapment efficiency of 72 ± 0.77 µm and 96.9 ± 0.52%, respectively. The microsponge gel showed the controlled release and was nonirritant to the rat skin. In creep recovery test it had shown highest recovery indicating elasticity. The controlled release of oxybenzone from microsponge and barrier effect of gel result in prolonged retention of oxybenzone with reduced permeation activity. Conclusion. Evaluation study revealed remarkable and enhanced topical retention of oxybenzone for prolonged period of time. It also showed the enhanced sun protection factor compared to the marketed preparation with reduced irritation and toxicity.


RSC Advances ◽  
2020 ◽  
Vol 10 (44) ◽  
pp. 26268-26276
Author(s):  
Michael Jackson Ferreira da Silva ◽  
Alisson Mendes Rodrigues ◽  
Italo Rennan Sousa Vieira ◽  
Gelmires de Araújo Neves ◽  
Romualdo Rodrigues Menezes ◽  
...  

A stable moisturizing cosmetic emulsion was developed from babassu nut oil and high concentrations of sunscreens.


Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 16 ◽  
Author(s):  
Muhammed Majeed ◽  
Shaheen Majeed ◽  
Renuka Jain ◽  
Lakshmi Mundkur ◽  
H. R. Rajalakshmi ◽  
...  

Ultraviolet (UV) rays and its harmful effects have always been a concern to skin health. Sunscreen and sunblock prevent the harmful effects of UV radiation on the skin. Sun Protection Factor (SPF) is an indication of the sun-protective capacity of an ingredient. There is an ever increasing interest in the cosmetic industry for developing novel functional ingredients from natural sources. The purpose of this study was to determine in-vitro and in vivo SPF of natural 90% pterostilbene extracted from the dried heartwood of Pterocarpus marsupium (Indian Kino). The SPF of purified pterostilbene and a formulation containing 0.4% pterostilbene was determined In Vitro using a UV spectrophotometer. Pterostilbene had an SPF of 21.73 ± 0.06, while the cream formulation had an SPF of 8.84 ± 0.01. The in vivo SPF of the 0.4% pterostilbene cream in humans was found to be 6.2 ± 1.30. Primary skin irritation tests in human subjects showed the formulation was safe and had no irritation potential. Pterostilbene was also found to have significant antioxidant activity as determined by free radical scavenging assays in vitro. These results suggest that natural pterostilbene is an antioxidant and shows SPF value both in-vitro and in the human clinical study and thus could be used as an ingredient in topical sun-protective formulations.


2021 ◽  
Vol 4 (2) ◽  
pp. 78-83
Author(s):  
Dita Ayulia Dwi Sandi ◽  
Eka Fitri Susiani ◽  
I Ketut Adnyana ◽  
Pratiwi Wikaningtyas

Sunscreen is a cosmetic substance that has the ability to reflect or absorb sunlight actively. It can prevent skin irritation due to UV rays. One of the natural ingredients with a sunscreen effect is the Edible-nest swiftlet's (Aerodramus fuciphagus) nest (ESN). This study aimed to determine the value of the sun protective factor (SPF) of the ESN water extract. The ESN water extract solution with variation concentration, this is 2000, 2500, 5000, 6000, and 7000 ppm, were measured by spectrophotometric UV-Vis at wavelength 290-375 nm with 5 nm intervals to determine the value of SPF, percentage of erythema transmission (%Te), and percentage of pigmentation transmission (%Tp) of ESN water extract. The result showed that the ESN water extract's SPF values at the concentration 2000, 2500, 5000, 6000, and 7000 ppm were 7.80; 9.68; 18.75; 20.58; and 22.24. The value of %Te of each concentration were 15.60±0.19; 10.03±0.42; 1.24±0.04; 0.81±0.01 and 0.56±0.01. While the value of %Tp of each concentration was showed the sunblock category. In conclusion, the ESN water extract from Central Kalimantan at the concentration of 6000 ppm has potential in ultraviolet protection against the skin in the ultra category with sunblock category mechanism. Further, it can be developed into sunscreen cosmetics from natural ingredients.


RSC Advances ◽  
2020 ◽  
Vol 10 (46) ◽  
pp. 27531-27531
Author(s):  
Michael Jackson Ferreira da Silva ◽  
Alisson Mendes Rodrigues ◽  
Italo Rennan Sousa Vieira ◽  
Gelmires de Araújo Neves ◽  
Romualdo Rodrigues Menezes ◽  
...  

Correction for ‘Development and characterization of a babassu nut oil-based moisturizing cosmetic emulsion with a high sun protection factor’ by Michael Jackson Ferreira da Silva et al., RSC Adv., 2020, 10, 26268–26276, DOI: 10.1039/D0RA00647E.


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