Novel Synthesis of 2-thienylcarbonyl-cyclohexane-1,3-dione as Building Block for Indazolones and Isoxazolones

2011 ◽  
Vol 64 (5) ◽  
pp. 638 ◽  
Author(s):  
Guillermo M. Chans ◽  
Elizabeth L. Moyano ◽  
Gloria I. Yranzo
Keyword(s):  
Nmr Spectroscopy ◽  
Ultrasonic Treatment ◽  
Building Block ◽  
Structural Elucidation ◽  
Synthetic Methodology ◽  
Novel Synthesis ◽  
Carbonyl Chloride

A new synthetic methodology using ultrasonic treatment was applied to the C-acylation of 1,3-cyclohexanedione with thiophene-2-carbonyl chloride to afford 3-hydroxy-2-(2-thienylcarbonyl)cyclohex-2-en-1-one (5). This compound was used as a building block to prepare different bicyclic systems: tetrahydro-4H-indazol-4-ones (7a–c and 9a,b,d), and 6,7-dihydrobenzisoxazole (11) by reaction with different hydrazines and hydroxylamine, respectively. Structural elucidation of all compounds was thoroughly achieved by NMR spectroscopy.

scholarly journals Improved Structural Elucidation of Synthetic Polymers by Dynamic Nuclear Polarization Solid-State NMR Spectroscopy

2013 ◽  
Vol 2 (8) ◽  
pp. 715-719 ◽  
Author(s):  
Olivier Ouari ◽  
Trang Phan ◽  
Fabio Ziarelli ◽  
Gilles Casano ◽  
Fabien Aussenac ◽  
...  
Keyword(s):  
Solid State ◽  
Nmr Spectroscopy ◽  
Dynamic Nuclear Polarization ◽  
Solid State Nmr ◽  
Nuclear Polarization ◽  
Synthetic Polymers ◽  
Structural Elucidation ◽  
Solid State Nmr Spectroscopy

scholarly journals 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

Molecules ◽  
2011 ◽  
Vol 16 (8) ◽  
pp. 6502-6511 ◽  
Author(s):  
Yahia Nasser Mabkhot ◽  
Abdullah Mohammed Al-Majid ◽  
Assem Barakat ◽  
Saeed Alshahrani ◽  
Yamin Siddiqui
Keyword(s):  
Building Block ◽  
Heterocyclic Synthesis ◽  
Pyrimidine Derivatives ◽  
Novel Synthesis

Structural Elucidation of Cryptic Algaecides in Marine Algal‐Bacterial Symbioses by NMR Spectroscopy and MicroED

2021 ◽  
Author(s):  
Jong-Duk Park ◽  
Yuchen Li ◽  
Kyuho Moon ◽  
Esther J. Han ◽  
Seoung Rak Lee ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Structural Elucidation ◽  
Marine Algal
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