Room Temperature Suzuki Reactions in Aqueous Media under Air by Palladium(II) Complexes with Pyrazole Derived Ligands

2010 ◽  
Vol 63 (2) ◽  
pp. 315 ◽  
Author(s):  
Kai Xu ◽  
Xin-Qi Hao ◽  
Jun-Fang Gong ◽  
Mao-Ping Song ◽  
Yang-Jie Wu
Keyword(s):  
Aqueous Solution ◽  
13C Nmr ◽  
Room Temperature ◽  
Phenylboronic Acid ◽  
Aqueous Media ◽  
Palladium Complexes ◽  
Coupling Reactions ◽  
X Ray ◽  
Suzuki Reactions ◽  
Aryl Bromides

Two new palladium complexes with pyrazole derived ligands 2a–2b have been easily prepared and well characterized by elemental analysis, 1H NMR, 13C NMR, and IR spectra. Their detailed structures are determined by a single-crystal X-ray analysis of 2a. The two compounds were successfully applied to the Suzuki coupling reactions of aryl bromides with phenylboronic acid, in aqueous solution at room temperature under air, giving the desired coupled products in good to excellent yields with catalyst loadings as low as 0.01–0.05 mol-%.

Synthesis, characterization, and application of palladium complexes containing 8-quinolylphosphinite ligands

2010 ◽  
Vol 88 (2) ◽  
pp. 99-103 ◽  
Author(s):  
Earl Cook ◽  
Jason D. Masuda ◽  
Aibing Xia
Keyword(s):  
Solid State ◽  
Single Crystal ◽  
Phenylboronic Acid ◽  
Suzuki Coupling ◽  
Palladium Complexes ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
X Ray Diffraction ◽  
X Ray ◽  
Solid State Structures

Palladium complexes containing 8-quinolylphosphinite ligands have been synthesized and characterized. Their solid state structures were determined by single-crystal X-ray diffraction. They were found to be active catalysts for Suzuki coupling reactions of phenylboronic acid and various aryl halides.

Synthesis, Characterization, and Crystal Structures of Three cis/trans Pyridine - Cyclopalladated Ferrocenylimine Complexes, and Their Catalysis in Suzuki Reactions

2007 ◽  
Vol 60 (3) ◽  
pp. 190 ◽  
Author(s):  
Chen Xu ◽  
Jun-Fang Gong ◽  
Yan-Hui Zhang ◽  
Yu Zhu ◽  
Yang-Jie Wu
Keyword(s):  
Solid State ◽  
Ir Spectra ◽  
Single Crystal ◽  
1H Nmr ◽  
Elemental Analysis ◽  
Phenylboronic Acid ◽  
Suzuki Reaction ◽  
X Ray ◽  
Suzuki Reactions ◽  
Aryl Bromides

Three new pyridine–cyclopalladated ferrocenylimine complexes 2a–c have been easily prepared and characterized by elemental analysis, ESI-MS, 1H NMR, and IR spectra. Their detailed structures are determined by single-crystal X-ray analysis. Palladacycle 2a is found to be a cis complex in the solid state, while 2b and 2c are trans complexes. These complexes were found to be efficient for the Suzuki reaction of aryl bromides with phenylboronic acid. Typically, using 0.2 mol% of 2c in the presence of 1.5 equivalents of K2CO3 as base in toluene at 100°C provided the coupled products in good to excellent yields.

Synthesis, characterization, and application of palladium complexes containing bis(aminophosphine) ligands

2017 ◽  
Vol 95 (10) ◽  
pp. 1041-1044 ◽  
Author(s):  
Christina Jones ◽  
Matthew Timm ◽  
Jason D. Masuda ◽  
Aibing Xia
Keyword(s):  
Single Crystal ◽  
Phenylboronic Acid ◽  
Suzuki Coupling ◽  
Palladium Complexes ◽  
Coupling Reactions ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
Aryl Chlorides

Two palladium complexes containing bis(aminophosphine) ligands have been prepared and characterized. Their solid structures were determined by X-ray single crystal diffraction studies. They were successfully employed in the Suzuki coupling reactions of phenylboronic acid and various aryl chlorides.

scholarly journals SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITY OF 7-HYDROXY-3',4'-DIMETHOXYFLAVONE

2012 ◽  
Vol 12 (2) ◽  
pp. 146-151 ◽  
Author(s):  
Elfi Susanti VH ◽  
Sabirin Matsjeh ◽  
Tutik Dwi Wahyuningsih ◽  
Mustofa Mustofa ◽  
Tri Redjeki
Keyword(s):  
Aqueous Solution ◽  
Antioxidant Activity ◽  
Sodium Hydroxide ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Room Temperature ◽  
Antioxidant Activities ◽  
Oxidative Cyclization ◽  
Dpph Method

Synthesis of flavones and their derivatives has attracted considerable attention due to their significant pharmaceutical effects. 7-hydroxy-3',4'-dimethoxyflavone has been synthesized and its antioxidant activity has been investigated. Flavone was synthesized by oxidative cyclization of chalcone. 2',4'-dihydroxy-3,4-dimethoxychalcone was prepared by Claisen-Schmidt condensation of 2,4-dihydroxyacetophenones with 3,4-dimethoxybenzaldehydes in the presence of aqueous solution of sodium hydroxide and ethanol at room temperature. Oxidative cyclization of 2',4'-dihydroxy-3,4-dimethoxychalcone was done by using I2 catalyst in DMSO to form 7-hydroxy-3',4'-dimethoxyflavone. The synthesized compounds were characterized by means of their UV-Vis, IR, 1H-NMR and 13C-NMR spectral data. The compound was tested for their antioxidant activities by DPPH method.

A Domino Reaction for the Synthesis of Novel 1,3-Dihydrofuro[3,4-c]pyridines from Pyridoxal and Ketones

Synthesis ◽  
2020 ◽  
Vol 53 (02) ◽  
pp. 365-370
Author(s):  
Lucas Pizzuti ◽  
Izamara Casadia ◽  
Thalita O. Daher ◽  
Sidnei Moura ◽  
Davi F. Back ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Nmr Spectroscopy ◽  
13C Nmr ◽  
Room Temperature ◽  
13C Nmr Spectroscopy ◽  
Domino Reaction ◽  
Alkyl Aryl ◽  
1H And 13C Nmr ◽  
X Ray ◽  
Pyridine Series

A convenient domino route for the synthesis of novel 1,3-dihydrofuro[3,4-c]pyridines from pyridoxal and alkyl, aryl or heteroaryl ketones under basic conditions is reported. A series of nine derivatives is obtained in 53–90% yields after stirring reactants for 48 hours at room temperature. Most products are easily isolated by filtration followed by recrystallization from ethanol. All products were fully characterized by FTIR, HRMS, and 1H and 13C NMR spectroscopy. The X-ray crystal structure of a representative example of the 1,3-dihydrofuro[3,4-c]pyridine series is also presented.

Sign in / Sign up

Export Citation Format

Share Document