scholarly journals Asymmetric Synthesis of ( - )-Swainsonine

2004 ◽  
Vol 57 (7) ◽  
pp. 669 ◽  
Author(s):  
Karl B. Lindsay ◽  
Stephen G. Pyne
Keyword(s):  
Asymmetric Synthesis ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis ◽  
New Synthesis

This paper describes a new synthesis of (–)-swainsonine via the ring-closing metathesis reaction of a substituted 3-allyl-4-vinyloxazolindin-2-one and subsequent diastereoselective syn-dihydroxylation of the resulting pyrrolo- [1,2-c]oxazol-3-one.

Formal Asymmetric Synthesis of (-)-Aphanorphine via Ring-Closing Metathesis Reaction

Synlett ◽  
2008 ◽  
Vol 2008 (18) ◽  
pp. 2821-2822 ◽  
Author(s):  
Zhong Li ◽  
Hongbin Zhai ◽  
Xiaobao Yang ◽  
Bin Cheng
Keyword(s):  
Asymmetric Synthesis ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis

A Double Ring Closing Metathesis Reaction in the Rapid, Enantioselective Synthesis of NK-1 Receptor Antagonists

2001 ◽  
Vol 3 (5) ◽  
pp. 671-674 ◽  
Author(s):  
Debra J. Wallace ◽  
Jonathan M. Goodman ◽  
Derek J. Kennedy ◽  
Antony J. Davies ◽  
Cameron J. Cowden ◽  
...  
Keyword(s):  
Enantioselective Synthesis ◽  
Metathesis Reaction ◽  
Receptor Antagonists ◽  
Ring Closing Metathesis ◽  
Double Ring

scholarly journals Synthesis of 2-aminosuberic acid derivatives as components of some histone deacetylase inhibiting cyclic tetrapeptides

2017 ◽  
Vol 13 ◽  
pp. 2153-2156 ◽  
Author(s):  
Shital Kumar Chattopadhyay ◽  
Suman Sil ◽  
Jyoti Prasad Mukherjee
Keyword(s):  
Amino Acid ◽  
Histone Deacetylase ◽  
Building Block ◽  
Suberic Acid ◽  
Metathesis Reaction ◽  
Cross Metathesis ◽  
Important Amino Acid ◽  
New Synthesis ◽  
Cyclic Tetrapeptides ◽  
Derivatives Of

A new synthesis of the important amino acid 2-aminosuberic acid from aspartic acid is reported. The methodology involves the alternate preparation of (S)-2-aminohept-6-enoate ester as a building block and its diversification through a cross-metathesis reaction to prepare the title compounds. The utility of the protocol is demonstrated through the preparation of three suberic acid derivatives of relevance to the design and the synthesis of peptides of biological relevance.

Synthesis of New Tricyclic Spirobispidines via Ring Closing Metathesis Reaction

Heterocycles ◽  
2007 ◽  
Vol 71 (11) ◽  
pp. 2331 ◽  
Author(s):  
Christian Hametner ◽  
Daniel Dangl ◽  
Kurt Mereiter ◽  
Martina Marchetti ◽  
Johannes Fröhlich
Keyword(s):  
Metathesis Reaction ◽  
Ring Closing Metathesis
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