scholarly journals The Acute Biochemical Response of the Starved Rabbit Liver in Situ to Glucose Infusion

1974 ◽  
Vol 27 (3) ◽  
pp. 249
Author(s):  
JF Williams ◽  
MG Irving ◽  
PF Blackmore ◽  
HL Regtop ◽  
MG Clark
Keyword(s):  
Fatty Acids ◽  
Blood Glucose ◽  
Free Fatty Acids ◽  
Pentose Phosphate Pathway ◽  
Pentose Phosphate ◽  
Rabbit Liver ◽  
Oxidative Pentose Phosphate Pathway ◽  
Glucose Levels ◽  
Blood Glucose Levels

Increasing the blood glucose levels from 88 to 400 mg/IOO ml in rabbit liver in situ during 5-min time intervals resulted in a decrease in the production of C02 from C-I of liver glucose together with a slight increase in the oxidation of C-6 of glucose; this was caused by a high glucose-induced decrease in the activity of the oxidative pentose phosphate pathway. Increasing the glucose concentrations also resulted in a threefold increase in the levels of palmitoyl- and stearoyl-CoA esters at a glucose load of 0�8 g; this is consistent with a specific feed-back inhibition of the production of NADPH by reactions of the oxidative pentose phosphate pathway by long-chain fatty acyl-CoAs. A decrease in plasma free fatty acids occurred when blood glucose levels were raised; this was associated with an increase in the concentration of free fatty acids in liver.

Effects of norepinephrine on blood glucose and free fatty acids in cold-adapted rats

1962 ◽  
Vol 203 (1) ◽  
pp. 95-97 ◽  
Author(s):  
Anne Davenport Rimmer ◽  
E. Schönbaum ◽  
E. A. Sellers
Keyword(s):  
Fatty Acids ◽  
Blood Glucose ◽  
Free Fatty Acids ◽  
Albino Rats ◽  
Blood Levels ◽  
Base Line ◽  
Time Intervals ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Slight Rise

Norepinephrine (0.5 mg) was given intraperitoneally to albino rats adapted to room temperature (23 C) and to cold (2 C). The rats were killed at selected time intervals thereafter, and the blood levels of free fatty acids (FFA) and glucose were estimated. Both groups showed an initial steep rise in blood FFA and a slight rise in blood glucose. After 1 hr the FFA levels were at their maximum in the 2 C rats but had fallen to nearly base-line levels in 23 C rats. Blood glucose levels remained slightly elevated for the whole 1-hr period in the 2 C rats, but in the 23 C rats a secondary greater rise took place toward the end of the period. Different metabolic responses follow the administration of a single dose of norepinephrine to 2 C and 23 C rats.

Response of Slovak Spotted cattle to stresses evoked by physical stimuli and the administration of pharmaceutical agents

1981 ◽  
Vol 33 (2) ◽  
pp. 195-198
Author(s):  
J. Jedliĉka ◽  
J. Mojto ◽  
J. Vanĉiŝin ◽  
E. Kmetová ◽  
S. Páleník
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Electric Shock ◽  
Blood Levels ◽  
Adrenocorticotrophic Hormone ◽  
Blood Samples ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Physical Stimuli ◽  
Pharmaceutical Agents

ABSTRACTNine bulls of the Spotted Slovak breed were exposed to different stressful stimuli. The stimuli used were noise, electric shock and the administration of insulin, adrenocorticotrophic hormone and the sedative xylazine (Rompun). The levels of glucocorticoids, free fatty acids and glucose were determined in blood samples obtained through a permanent, indwelling, jugular cannula. It was found that insulin, adrenocorticotrophic hormone and electric shock evoked significant increases in the concentration of glucocorticoids in the blood. Noise did not affect the blood level of glucocorticoids. The stimuli did not induce any change in the blood levels of free fatty acids. Blood glucose levels were increased following insulin, adrenocorticotrophic hormone, electric shock and xylazine but not following noise. Insulin, as expected, decreased the concentration of glucose in the blood.

scholarly journals Nutritional Analyses of Domestic and Poultry Chickens and Evaluation of the Subsequent Effects on Lowering Blood Glucose Levels in Alloxan-Induced Wister Rats

2021 ◽  
pp. 98-109
Author(s):  
Mahbuba Khatun ◽  
Md. Motiar Rahman ◽  
M. Manirujjaman ◽  
Meftah Uddin ◽  
Mst. Gulshan Ara ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Blood Glucose ◽  
Essential Fatty Acids ◽  
Gas Liquid Chromatography ◽  
Omega 3 ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Omega 6 ◽  
Macro And Micronutrients

In the recent decades, peoples concentrate more on reduced-consumption of diets containing saturated fatty acids and replace them with essential polyunsaturated ones, including omega-3 and omega-6 fatty acids, due to their promising nutritional benefits. Therefore, the production of chicken meat having lower fat compositions, and riches in pro-healthy fatty acid and other macro-and micronutrients deserves great attention in the food industry. The research aimed to characterize meat oils of two commercially available, domestic and poultry, chickens in the Northern part of Bangladesh (Rajshahi), followed by the investigation of their nutritional compositions and hypoglycemic effect in vivo. In this work, the oil was isolated from the dried meat sources by Soxhlet extractor and purified using a rotary evaporator. We subsequently characterized meat oil in terms of various parameters, such as iodine value, saponification number, unsaponifiable matter, free fatty acid (FFA) contents, peroxide value, and acid value. Besides, the nutritional parameters of chicken oil were investigated as percentages of essential fatty acids and several other micro-and macronutrients using gas-liquid chromatography and other conventional methods. Finally, Alloxan-induced Wister rats were fed with oil and chicken flesh to investigate the hypoglycemic effects. The experimental analyses show that chicken oil possesses a significant proportion of omega-3 and omega-6 fatty acid, macro-and micronutrients. Besides, oil and flesh were found to lower blood glucose levels in diabetic rats despite flesh could not significantly show hypoglycemic properties.

scholarly journals A system for the study in situ of the pentose phosphate pathway in rabbit liver

1971 ◽  
Vol 123 (5) ◽  
pp. 915-922 ◽  
Author(s):  
J. F. Williams ◽  
K. G. Rienits ◽  
M. G. Clark
Keyword(s):  
Pentose Phosphate Pathway ◽  
Adenine Nucleotide ◽  
Glucose Production ◽  
Systemic Circulation ◽  
Pentose Phosphate ◽  
Rabbit Liver ◽  
Homogeneous Distribution ◽  
Body Tissues ◽  
Minute Interval

A surgical procedure for the isolation of the liver from the systemic circulation of the anaesthetized rabbit is described. The technique allowed the metabolism in situ of intraportally infused substrates to be followed for periods up to 5min, free from the contaminating influences of metabolism by other body tissues. Details of the procedures necessary to achieve the uniform infusion, homogeneous distribution and containment of 14C-labelled glucose substrates in the liver by haemostasis are described. Changes in pO2, pCO2, pH and the concentrations of NADP+, NADPH and glucose during each minute interval of the total 5min period of metabolism are given. Reactant ratios of the lactate dehydrogenase system and the adenine nucleotide system have been calculated from the concentrations of the pertinent metabolites for the same period of metabolism. Glucose production by rabbit liver in situ proceeded at the rate of 1.08μmol/min per g wet wt. of liver during the 5min metabolic interval. The presence of the oxidative reactions of the pentose phosphate pathway of glucose metabolism was inferred from the quotient oxidation of [1-14C]glucose/oxidation of [6-14C]glucose=1.8.

Intraoperative Changes in Blood Glucose Levels Increase the Risk of Death in Cardiac Surgery

2006 ◽  
Vol 31 (03) ◽  
Author(s):  
H Hager ◽  
E Giorni ◽  
A Felli ◽  
B Mora ◽  
M Hiesmayr ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Glucose ◽  
Glucose Levels ◽  
Risk Of Death ◽  
Blood Glucose Levels

2167-PUB: Effect of Low-Available Carbohydrate Diet Containing Okara and Konjac on Blood Glucose Levels in Spontaneous Diabetic Torii Fatty Rats

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2167-PUB
Author(s):  
KOHEI SURUGA ◽  
TSUYOSHI TOMITA ◽  
MASAKAZU KOBAYASHI ◽  
TADAHIKO MITSUI ◽  
KAZUNARI KADOKURA
Keyword(s):  
Blood Glucose ◽  
Carbohydrate Diet ◽  
Glucose Levels ◽  
Blood Glucose Levels
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