The effect of water restriction on some physiological responses of steers during enforced exercise in a warm environment

1980 ◽  
Vol 31 (2) ◽  
pp. 409 ◽  
Author(s):  
PJ Schmidt ◽  
NTM Yeates ◽  
DM Murray
Keyword(s):  
Temperature Response ◽  
Control Group ◽  
Evaporative Heat Loss ◽  
Water Restriction ◽  
Water Control ◽  
Once Daily ◽  
Warm Environment ◽  
Restricted Group ◽  
Access To Water ◽  
Body Heat

Two groups of steers, accustomed to drinking either once daily in the afternoon every other day or twice daily, were subjected to enforced exercise in a warm environment for four consecutive days. Animals in the restricted watering group were exercised both 42 h (days 1 and 3) and 18 h (days 2 and 4) after having access to water. Control animals watered twice daily commenced exercise 2 h after watering on all four days. On days 1 and 3, the restricted group exhibited higher rectal temperatures and lower respiratory rates with exercise than the control group. On days 2 and 4, restricted animals displayed both lower rectal temperatures and respiratory rates than control animals. Measurements of sweating rate and feed intake are reported. These data suggest that neither evaporative heat loss from the skin nor body heat production was implicated in the lower rectal temperature response of restricted animals on days 2 and 4. It is suggested that the lower rectal temperatures of restricted animals during exercise on days 2 and 4 may be related to their greater water intakes at the afternoon watering on days 1 and 3.

The effect of diet and frequency of watering on rumen degradability and outflow rate of low-quality veld hay and dry-matter apparent digestibility in steers given food at maintenance

1997 ◽  
Vol 65 (2) ◽  
pp. 159-164 ◽  
Author(s):  
S. Sibanda ◽  
P. R. Hatendi ◽  
F. M. Mulenga ◽  
P. Ndlovu
Keyword(s):  
Dry Matter ◽  
Latin Square ◽  
Metabolizable Energy ◽  
Free Access ◽  
Apparent Digestibility ◽  
Water Restriction ◽  
Once Daily ◽  
Degradation Pattern ◽  
Outflow Rate ◽  
Access To Water

AbstractThe effect of water restriction on rumen degradability and outflow rate of low quality veld hay and dry-matter apparent digestibility was investigated in four rumen cannulated Tuli × Friesian steers (mean weight 329 (s.d. 36·6) kg) given food at maintenance (metabolizable energy allowance (maintenance) (MJ) = 8·3 + 0·091 M). Two diets with 20: 80 (low, L) and 80:20 (high, H) roughage to concentrate ratios were used in combination with free access to water for 2·5 h once daily or once every 3rd day. A 4 × 4 Latin-square design with a 2 (diets) × 2 (watering frequencies) factorial arrangement of treatments was used.The degradation pattern of veld hay was not affected by the type of diet and the watering frequency. Although the effective degradabilities of hay in steers given the two diets were low (177 and 258 g/kg for L and H, respectively), they were significantly different (P < 0·05) from each other. However, watering frequency did not affect the effective degradability of hay (218 and 217 g/kg). While the low roughage diet had a higher rumen outflow rate for Crmordanted hay than the high roughage diet (0·047 per h and 0·031 per h), this was not statistically significant. The same outflow rate was obtained for the two watering frequencies (0·039 per h).

145 THE INFLUENCE OF PROPYLENE GLYCOL DRENCHING ON THE SUPEROVULATORY RESPONSE AND EMBRYO QUALITY IN HIGH-YIELDING DAIRY COWS

2015 ◽  
Vol 27 (1) ◽  
pp. 164
Author(s):  
T. Othman ◽  
S. Ismael ◽  
M. Ayoub
Keyword(s):  
Oral Dose ◽  
Dairy Cows ◽  
Propylene Glycol ◽  
Genetic Improvement ◽  
Embryo Quality ◽  
The Other ◽  
Control Group ◽  
Water Control ◽  
Once Daily ◽  
Grade 3

Genetic improvement of dairy cows increased markedly over the last decades; this has marked increased milk yield, which has been associated with reduced fertility parameters. The objective of this study was to determine the effects of feeding propylene glycol (PG) on superovulatory responses of 50 dairy cows and on their embryo quality and quantity. Starting at 1 week before the application of superovulatory regimen, each cow received once daily an oral dose of 150 g of PG (PG group) or water (control group). All cows were superovulated with a total dose of 400 mg of FSH administrated twice daily in decreasing doses over 4 consecutive days. Embryos were recovered nonsurgically 7.5 days after the onset of oestrus using a 2-way catheter. Evaluation of embryo quality was done according to the IETS manual based on 1 to 4 grades. Grade 1 embryos were transferred after freezing; grade 2 and 3 embryos were freshly transferred. The results showed that the number of total ova/embryos recovered, grade 1 embryos, and the number of transferable embryos were significantly higher (P = 0.048, 0.015, and 0.014, respectively) in the PG group (10.33 ± 1.9, 7.08 ± 1.7, and 7.92 ± 1.6, respectively) when compared with control group (6.09 ± 0.9, 2.11 ± 0.45, and 3.92 ± 1.25, respectively). Insignificant increase in grade 2 and grade 3 embryos was indicated in the control group (1.37 ± 0.3 and 0.51 ± 0.18, respectively) when compared with PG group (0.75 ± 0.28 and 0.25 ± 0.13, respectively). On the other hand, the results indicated that there was an increase in the number of degenerated embryos and unfertilized ovum in the PG group (2.33 ± 0.85) compared with control group (2.09 ± 0.6). In conclusion, these results suggested that administration of PG has the ability to positively improve the superovulatory response and embryo quality in high-yielding dairy cows.

scholarly journals The metabolic disorders associated with chronic consumption of soft and energy drinks in rats*

2020 ◽  
Author(s):  
Heba M. Eltahir ◽  
Ghadi Alamri ◽  
Asmaa Alamri ◽  
Asmaa Aloufi ◽  
Maiiada Nazmy ◽  
...  
Keyword(s):  
Sugar Content ◽  
Energy Drinks ◽  
Control Group ◽  
Albino Rats ◽  
Free Access ◽  
Metabolic Disturbances ◽  
Water Control ◽  
Negative Effects ◽  
Access To Water ◽  
Group 2

Background: Energy Drinks (EDs) and Soft Drinks (SDs) are widely consumed among adolescents and young adults. These drinks contain variable amounts of caffeine which is a central nervous system stimulator; in addition to sugar, taurine, vitamins and herbal extracts. Several adverse effects have been reported for the excessive consumption of caffeine and sugar. Aim: This work aimed at providing a comparison between the effect of chronic consumption of both drinks on metabolism biochemically as well as at the histopathological level. Methods: Adult albino rats were randomly divided into three groups and treated for 4 weeks. Animals received water (control, group 1), 12.5 ml/kg/day of either Pepsi® (SD, group 2) or Power Horse® (ED, group 3). All animals had free access to water and standard animal chow. Results: ED and SD groups showed a significant weight gain compared to control. ED animals showed a significant increase in serum urea, hyperlipidemia and hyperglycemia in comparison to control and SD groups. Serum uric acid significantly increased in ED and SD groups. ED group showed congestion and inflammation in their renal tissues in addition to splenomegaly and increased phagocyte infiltration. Conclusion: The high caffeine-sugar content in ED exerts a more significant influence on the metabolic pathways than SDs. Both increase the incidence of cardiovascular diseases and tissue inflammation due to their effect on lipid profile and blood glucose. The other ingredients in EDs may play a role in the observed metabolic disturbances. Chronic use of EDs should be especially discouraged to avoid these negative effects.

The effect of bromocriptine on mammary-gland ultrastructure of hyperprolactinemic rats

1984 ◽  
Vol 42 ◽  
pp. 204-205
Author(s):  
I.C. Murray
Keyword(s):  
Mammary Gland ◽  
Dopamine Agonist ◽  
Alveolar Epithelium ◽  
Mammary Glands ◽  
Female Rats ◽  
Control Group ◽  
Cell Hyperplasia ◽  
Once Daily ◽  
Long Evans

In women, hyperprolactinemia is often due to a prolactin (PRL)-secreting adenoma or PRL cell hyperplasia. RRL excess stimulates the mammary glands and causes proliferation of the alveolar epithelium. Bromocriptine, a dopamine agonist, inhibits PRL secretion and is given to women to treat nonpuerperal galactorrhea. Old female rats have been reported to have PRL cell hyperplasia or adenoma leading to PRL hypersecretion and breast stimulation. Herein, we describe the effect of bromocriptine and consequently the reduction in serum PRL levels on the ultrastructure of rat mammary glands.Female Long-Evans rats, 23 months of age, were divided into control and bromocriptine-treated groups. The control animals were injected subcutaneously once daily with a 10% ethanol vehicle and were later divided into a normoprolactinemic control group with serum PRL levels under 30 ng/ml and a hyperprolactinemic control group with serum PRL levels above 30 ng/ml.

scholarly journals Effect of Oral Gavage Dosing Regimens in Female Tg rasH2 Transgenic Mice

2004 ◽  
Vol 32 (4) ◽  
pp. 413-417 ◽  
Author(s):  
Daniel Morton ◽  
Rani S. Sellers ◽  
Sylvia M. Furst ◽  
Kristen D. Hawley ◽  
Jeffrey R. May
Keyword(s):  
Body Weight ◽  
Incidental Finding ◽  
Sodium Dodecyl ◽  
Control Group ◽  
Oral Gavage ◽  
Once Daily ◽  
Dosing Regimens ◽  
Rash2 Mice ◽  
Daily Water ◽  
Cortical Architecture

Female Tg rasH2 (CB6F1/Jic-TgrasH2@Tac) mice were administered water once daily, water twice daily with 8 or 12 hours between doses, 1% sodium dodecyl sulfate in water (1% SDS) once daily, or 1% SDS twice daily with 12 hours between doses by oral gavage at volumes of 10 ml/kg/day for 28 or 29 consecutive days. A control group of mice received no treatment and no sham manipulation. There were no significant differences in body weight or food consumption between treated groups and untreated control mice. Mean weights of spleens, livers, and thymuses were lower than control values in most groups of mice subjected to gavage. Focal or multifocal loss of thymic cortical architecture was observed in 13 of 50 mice distributed among all groups (including naïve controls), however only in one instance was this finding suggestive of a precursor to neoplasia. This study demonstrated that Tg rasH2 mice can tolerate once or twice daily gavage dosing with water or vehicle containing 1% SDS. Loss of thymic cortical architecture was a common incidental finding in female Tg rasH2 mice.

Maternal treatment with fluoxetine promotes testicular alteration in male rat pups

2016 ◽  
Vol 28 (8) ◽  
pp. 1206 ◽  
Author(s):  
Aline C. Ramos ◽  
Alice H. dos Santos ◽  
Kennia M. Silveira ◽  
Ana Carolina I. Kiss ◽  
Suzana F. P. Mesquita ◽  
...  
Keyword(s):  
Tap Water ◽  
Post Partum ◽  
Gonadosomatic Index ◽  
Male Offspring ◽  
Male Rat ◽  
Control Group ◽  
Maternal Behaviour ◽  
Testis Weight ◽  
Water Control ◽  
Maternal Treatment

Fluoxetine (FLX) is a selective serotonin reuptake inhibitor (SSRI) antidepressant commonly prescribed during pregnancy and lactation. Pre- and post-partum depression, as well as SSRI treatment during these periods, may change maternal care, interfering with offspring development. Moreover, it is known that SSRIs may alter testes structure and function in offspring. The present study investigated the effects of maternal FLX exposure on maternal behaviour and testes function in offspring. Female Wistar rats were treated with 7.5 mg kg–1 FLX or tap water (control group) by gavage from the Day 1 of pregnancy until 21 days after birth (postnatal Day (PND) 21). Maternal behaviour was evaluated and morphofunctional analyses of offspring testes were conducted on PND 21 and 50. There were no significant differences between the FLX-treated and control groups regarding maternal behaviour. Nor did maternal treatment with FLX have any effect on bodyweight gain, anogenital distance, day of preputial separation, testis weight and the gonadosomatic index in male offspring. However, there was a decreased number of Sertoli cells at both PND 21 and 50 in FLX-exposed male offspring. The findings of the present study demonstrate that maternal exposure to FLX can impair testicular function in weanling and pubertal animals.

scholarly journals Performance of sheep fed forage cactus with total water restriction

2017 ◽  
Vol 18 (2) ◽  
pp. 369-377 ◽  
Author(s):  
Alma Violeta CORDOVA-TORRES ◽  
Roberto Germano COSTA ◽  
Ariosvaldo Nunes de MEDEIROS ◽  
José Teodorico ARAÚJO FILHO ◽  
Alenice Ozino RAMOS ◽  
...  
Keyword(s):  
Water Intake ◽  
Control Diet ◽  
Food Supplement ◽  
Daily Weight Gain ◽  
Control Group ◽  
Total Water ◽  
Water Restriction ◽  
Mineral Mixture ◽  
Dunnett's Test ◽  
Nopalea Cochenillifera

SUMMARY A lack of water in livestock production can limit the performance of the animals; therefore, the objective of this study was to evaluate the effect of water restriction on the growth performance of sheep that were fed forage cactus (Nopalea cochenillifera). Forty-two male sheep were used, with an average age and weight of ±100 days and 18.75 ± (2,05) kg , respectively, and they were fed diets containing concentrate, mineral mixture and three levels of substitution (30, 50 and 70%) of Tifton hay with forage cactus (Nopalea cochenillifera). The animals were slaughtered when they reached 32 kg (± 1 kg) of body weight or 90 days. The experimental design was a 3x2 factorial arrangement, forage cactus (30, 50, 70%) x water (with or without water) plus a control group (n=6). Variables were analyzed using Tukey and Dunnett's test at 5% with PROC GLM in SAS software. Voluntary water intake and dry matter intake (DMI) decreased with the inclusion of forage cactus; however, preformed water intake and total water intake increased with the inclusion of forage cactus. Water restriction and its interaction with the treatments had no effect on animal performance. Daily weight gain was higher for the diets with 30 and 50%forage cactus inclusion, at 174 and 155 g, respectively, compared with 90 g for the control diet. Cactus, therefore, can be used as a food supplement and water resource.

THE UPTAKE OF TRITIATED LYSINE VASOPRESSIN BY RAT AND PIG PITUITARY NEURAL LOBES IN VITRO

1971 ◽  
Vol 50 (4) ◽  
pp. 669-677 ◽  
Author(s):  
B. A. EDWARDS
Keyword(s):  
Tap Water ◽  
Exchange Chromatography ◽  
Control Group ◽  
Breakdown Product ◽  
Nacl Solution ◽  
Water Control ◽  
Neural Lobe ◽  
Lysine Vasopressin ◽  
And Control

SUMMARY Uptake of tritiated lysine vasopressin ([3H]LVP) was studied in halved neural lobes of rats (which had been given either tap water (control group) or 2% (w/v) NaCl solution as drinking water for 4 days) as well as in slices of pig neural lobe. Uptake of radioactivity into the neural lobes was shown but analysis of the extracts of incubated lobes of both species by ion exchange chromatography showed that very little of it remained in the tissue as hormone. In addition, some radioactivity was associated with trichloroacetic acid-insoluble proteins. After 90 min of incubation, and after correction for the breakdown, the uptake of unchanged [3H]LVP, expressed as a tissue: medium ratio, was 0·14 ± 0·04 and 0·09 ± 0·03 (mean ± s.e.m.) for the saline-treated and control rats respectively, while the tissue: medium ratios for the breakdown product(s) were 6·47 ± 0·45 and 5·50 ± 0·36. The results suggest uptake of [3H]LVP into the cell with almost complete intracellular breakdown of the hormone.

Effects of GYDENPHY caspules on streptozotocin-induced type 1 diabetic in Swiss mouse model

2021 ◽  
Vol 25 (2) ◽  
pp. 24-32
Author(s):  
Trinh Thach Thi Nguyen ◽  
Duy Tuan Nguyen ◽  
Thanh Ha Tuan Nguyen ◽  
Thi Huong Lan Do ◽  
Hoang Ngan Nguyen
Keyword(s):  
Blood Glucose ◽  
Mouse Model ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Insulin Injection ◽  
Swiss Mouse ◽  
Hypoglycemic Effect ◽  
Control Group ◽  
Water Control

Objective: Evaluation the hypoglycemic effect of Gydenphy capsules on Streptozotocin-induced type 1 diabetic in Swiss mouse model. Methods: The type 1 diabetic model was established by intraperitoneal injections of Streptozocin 150mg/kg in Swiss mouse. Then, the Gydenphy were orally administered daily at a dose of 576 mg/kg/day or 1152 mg/kg/day in 10 days. Blood glucose concentration in the Gydenphy oral groups with that of water control group and the intraperitoneal insulin injection group was compared. Results: Blood glucose concentration in the groups using Gydenphy (dose576 mg/kg/24h and dose 1152 mg/kg/24h) significal decreased compared to the distilled water group at (p <0.05 at the time of 4 hours, 8 hours; p <0.01 at the time of 3, 10 days). The hypoglycemic effect of Gydenphy at 576mg/kg/day and 1152 mg/kg/day at 4 hours, 8 hours and 3 days were inferior to insulin 0.1 UI/kg/day for glycemic control. However, the hypoglycemic effect ofGydenphy were equivalent to insulin after 10 consecutive days on treatment. Conclusion: Gydenphy capsules have hypoglycemic effects onStreptozotocin-induced type 1 diabetes in Swiss mouse model.

Effect of Experimentally Induced Chronic Kidney disease on Skeletal, Cardiac and Smooth Muscle fibers of albino rat

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ghada Lotfy ◽  
Amel Soliman ◽  
Nevine Bahaa ◽  
Mohammed Hegazi
Keyword(s):  
Skeletal Muscle ◽  
Chronic Kidney Disease ◽  
Smooth Muscle ◽  
Kidney Disease ◽  
Intramuscular Injection ◽  
Muscle Fibers ◽  
Lateral Wall ◽  
Control Group ◽  
Once Daily ◽  
Group Ii

Abstract Background Chronic kidney disease (CKD), or chronic renal failure (CRF) as it was historically termed, includes all degrees of decreased renal function, starting from mild, and moderate, to severe chronic kidney failure. Skeletal muscle atrophy frequently complicates the course of CKD and is associated with excess morbidity and mortality. Cardiovascular diseases have been reported to be the leading causes of death in CKD patients. Chronic Kidney Disease was also reported to be associated with an increased incidence of acid-related gastrointestinal disorders. Aim of the work The aim of this study was to investigate the effect of chronic kidney disease experimentally induced by gentamicin intramuscular injection on the histological structure of gastrocnemius skeletal muscle, left ventricular cardiac muscle and smooth muscle fibers of lower esophagus. Materials and methods Twenty male adult Wistar albino rats were randomly and equally divided into two groups. Group I (control group) received physiological saline intramuscular injection, once daily for 28 consecutive days, in a dose equivalent to that taken in group II. Group II (Gentamicin-treated group) were given Gentamicin intramuscular injection for induction of CKD. Gentamicin was given as Gentamycin sulfate, 40 mg/ml (Sandoz, Switzerland), once daily, in a dose of 80 mg/kg/day for 28 days to induce CKD. After 28 days of the first injection of gentamicin, rats were anaesthetized and blood samples were collected to measure the level of serum urea and creatinine. The left kidneys, the middle third of left gastrocnemius muscle, the lateral wall of left ventricle (LV) and the gastroesophageal junction of all rats of both groups (I and II) were processed for light microscopic study. The middle third of left gastrocnemius muscle, the lateral wall of left ventricle (LV) were further processed for transmission electron microscopic study. Histomorphometrical and statistical analysis were also done. Results The LM examination revealed moderate obliteration of glomeruli, dilatation in some renal tubules and collapse in others, mainly in distal convoluted tubules, with significant fibrosis of renal parenchyma. Serum urea and creatinine levels were increased significantly. The skeletal muscle fibers of the rats in group II (CKD) showed focal areas of myofibers degeneration with siginificant fibrosis. The cardiac muscle fibers of the rats in the group II (CKD) showed focal areas of cardiomyocytes degeneration and other areas of significantly hypertrophied fibers. The smooth muscle fibers of the lower esophageal sphincter of the rats in group II (CKD) showed no significant structural changes compared with the control group, however, the myenetric plexus showed multiple pyknotic and karyolitic nuclei with vacuolated cytoplasm. In addition, insignificant increase in the amount of collagen fibers was observed in almost all layers. Conclusion CKD produced moderate atrophy of skeletal muscle fibers, significant increase in the cardiomyocyte size and no significant structural effect of smooth muscle fibers of the lower esophageal sphincter.

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