The effect of residual grain on the utilization of sweet lupin stubbles and concurrent changes associated with lupinosis, in particular changes in liver copper and zinc in weaner sheep

1979 ◽  
Vol 30 (5) ◽  
pp. 929 ◽  
Author(s):  
KP Croker ◽  
JG Allen ◽  
HG Masters ◽  
DS Petterson
Keyword(s):  
Liver Damage ◽  
Plasma Glucose ◽  
Lupinus Angustifolius ◽  
Stocking Rate ◽  
Liver Copper ◽  
Copper And Zinc ◽  
Peak Weight ◽  
Zinc Levels

An experiment was conducted with Merino wether weaners to examine the influence of lupin grain on the utilization of stubbles from crops of sweet, narrow-leafed lupins (Lupinus angustifolius cv. Unicrop). Sheep grazed at 25 ha-1 without additional grain or with grain (350 kg ha-1) added to the stubble gained weight over 65 days, but those with the additional grain grew faster (av. 126 v. 77 g d-1). At 50 ha-1, sheep grazed on normal stubble gained weight for only 44 days at a mean rate of 82 g d-1, while those with the additional grain (350 kg ha-1) reached a peak weight after 65 days of little growth (31 g d-1). The sheep developed lupinosis. Those grazed at 50 ha-1 suffered more liver damage than those at 25 ha-1, and liver copper levels increased while zinc levels decreased as the severity of liver damage increased. Plasma ornithine carbamyl transferase (OCT) was of minimal value in the diagnosis of lupinosis.The levels of plasma glucose were generally higher in the sheep grazed at the low stocking rate.

Utilization of lupin stubbles by merino sheep: studies of animal performance, rates and time of stocking, lupinosis, liver copper and zinc, and circulating plasma enzymes

1979 ◽  
Vol 30 (3) ◽  
pp. 551 ◽  
Author(s):  
KP Croker ◽  
JG Allen ◽  
DS Petterson ◽  
HG Masters ◽  
RF Frayne
Keyword(s):  
Liver Damage ◽  
Significant Negative Correlation ◽  
Zinc Level ◽  
Copper Level ◽  
Liver Copper ◽  
Plasma Enzymes ◽  
Copper And Zinc ◽  
Phomopsis Leptostromiformis ◽  
Zinc Levels ◽  
Stocking Rates

Three experiments were conducted in the West Midland region of Western Australia to evaluate the sheep-carrying capacity of dry narrow-leafed sweet lupin (Lupinus angustifolius cv. Uniharvest) stubbles. In addition, the effect of stocking rate on lupinosis, and the effect of lupinosis on circulating plasma enzymes and liver copper and zinc levels were determined. At low stocking rates (25 or less ha-1) sheep were grazed for up to 80 days with increases in liveweight. However, with higher stocking rates (50 or 75 ha-1) the maximum weights obtained were lower, and reached after a shorter period of time. Sheep grazed at the high stocking rates suffered more liver damage than those grazed at low rates, and it is suggested that outbreaks of clinical lupinosis might be precipitated by grazing sheep at high rates. Sheep that grazed the stubbles and suffered liver damage had higher liver copper levels than those that suffered no damage. Also, there was an indication that the degree of liver damage and the liver copper level were directly related. It is suggested that the toxins of Phomopsis leptostromiformis cause the liver to take up and store copper. A significant negative correlation between the degree of liver damage and the liver zinc level was found. However, it was not determined whether this diminishment of liver zinc was a direct effect of the toxins of P. leptostromiformis or due to displacement by copper which was actively being taken up. Plasma levels of ornithine carbamyl transferase, alkaline phosphatase and aspartate amino transferase, measured during or at the end of the experiments, were not related to the degree of terminal liver injury. They are not considered reliable indicators of the incidence or severity of lupinosis in the field.

scholarly journals Superoxide dismutase (EC1.15.1.1), manganese and the effect of ethanol in adult and foetal rats

1982 ◽  
Vol 48 (2) ◽  
pp. 205-210 ◽  
Author(s):  
I. E. Dreosti ◽  
Susan J. Manuel ◽  
R. A. Buckley
Keyword(s):  
Superoxide Dismutase ◽  
Manganese Superoxide Dismutase ◽  
Aqueous Ethanol ◽  
Adult Rats ◽  
Liver Copper ◽  
Copper And Zinc ◽  
Manganese Superoxide ◽  
Maternal Alcoholism ◽  
Zinc Levels

1. The activity of manganese-superoxide dismutase (EC1.15.1; SOD) was increased in the livers and kidneys of adult rats after exposure to aqueous ethanol (200 ml/l) for 32 weeks.2. The concentration of Mn in the livers and kidneys was significantly higher after 24 weeks, and by 32 weeks liver copper and zinc levels were lower.3. The activity of foetal (day 19) liver superoxide dismutase was appreciably higher in offspring from dams receiving ethanol during pregnancy. Quantitatively the response appeared to be almost entirely due to the Mn-SOD form of the enzyme.4. Maternal alcoholism during pregnancy had no effect on the levels of Cu, Mn or Zn in foetal (day 19) livers.

Serum copper and zinc levels and copper/zinc ratio in patients with breast cancer

1994 ◽  
Vol 40 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Idris Yücel ◽  
Fikret Arpaci ◽  
Ahmet Özet ◽  
Bülent Döner ◽  
Turan Karayilanoĝlu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Copper Zinc ◽  
Zinc Levels

scholarly journals Serum copper and zinc levels at diagnosis and hepatocellular carcinoma survival in the Guangdong Liver Cancer Cohort

2019 ◽  
Vol 144 (11) ◽  
pp. 2823-2832 ◽  
Author(s):  
Ai‐Ping Fang ◽  
Pei‐Yan Chen ◽  
Xiao‐Yan Wang ◽  
Zhao‐Yan Liu ◽  
Dao‐Ming Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Levels

Cadmium, Copper, and Zinc Levels in Rice and Soil of Japan, Indonesia, and China by Soil Type

2000 ◽  
Vol 64 (1) ◽  
pp. 33-39 ◽  
Author(s):  
N. Herawati *, ‡ , S. Suzuki ◽  
K. Hayashi ◽  
I. F. Rivai
Keyword(s):  
Soil Type ◽  
Copper And Zinc ◽  
Zinc Levels
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