Effectiveness of intravenous and abomasal doses of mimosine for defleecing sheep and effects on subsequent wool growth

1978 ◽  
Vol 29 (5) ◽  
pp. 1043 ◽  
Author(s):  
PJ Reis

Four Merino sheep were given intravenous infusions of mimosine for 2 days at a rate of 110–120 mg/kg/day. Wool fibre growth stopped by about 1 day after the start of the infusions, and the sheep were subsequently manually defleeced. It was estimated that, on average, fibre growth stopped for about 12 days. Wool growth rates were above the pre-infusion rates in the early regrowth (3–5 weeks after dosing), and the mean fibre diameter was still about 2 µm above pre-infusion values at 11 weeks after dosing. Groups of Merino sheep were given intravenous infusions of mimosine for 2 days at rates ranging over 40–320 mg/kg/day. The minimal rate of infusion required to produce consistent defleecing was 80 mg/kg/day; infusions at a rate of 60 mg/kg/day were sometimes effective for defleecing, but at 40 mg/kg/day produced no discernible effects on the strength of wool fibres. No adverse effects were observed at a mimosine infusion rate of 80 mg/kg/day, but one out of four sheep died when dosed at a rate of 160 mg/kg/day, and higher rates (240 and 320 mg/kg/day) were lethal. The concentration of mimosine in plasma was related to the rate of infusion of mimosine. Consistent defleecing was associated with a concentration of mimosine in plasma approaching 100 µmoles/l; lethal doses resulted in plasma mimosine concentrations above 300 µmoles/l. Abomasal infusions of mimosine at a rate of 80 mg/kg/day were equivalent to intravenous infusions. Single injections of mimosine into the abomasum did not influence the strength of wool fibres; pIasma concentrations foIlowing injections indicated rapid absorption of mimosine and rapid removal from the body.

1998 ◽  
Vol 49 (8) ◽  
pp. 1187 ◽  
Author(s):  
N. R. Adams ◽  
J. R. Briegel

The present study examined changes in wool growth, liveweight, and body composition in groups of fine, medium, and broad wool Merino wethers grazed together at pasture in the highly seasonal Mediterranean environment, to determine the sources of variation in wool growth that may affect staple strength (SS). Seasonal changes in wool growth were measured using 6 dyebands placed at times of seasonal change in the nutrient supply from pasture, and liveweights were recorded fortnightly. Dilution of deuterated water was used to determine changes in body composition between the beginning of summer and the end of autumn. The sheep lost liveweight over this period, but loss of protein relative to fat over this period was unexpectedly high (7 : 1). The relative changes in liveweight, and loss of its components (fat and lean) during summer and autumn, were similar in all 3 groups, even though the Broad group was heavier than the other 2 genotypes at all times (P < 0·01). In contrast to the similar pattern of liveweight change, wool growth rates and changes in the fibre diameter were less variable throughout the year in the Broad group than the other 2 groups (P < 0·001). Stepwise regression indicated that the characteristics related to SS were standard deviation in fibre diameter (SDfd; P < 0·001), mean fibre diameter (P < 0·001), and variation in diameter within a 200-mm length of wool fibre (Sdfdwithin; P < 0·05). However, the relative importance of different factors for SS differed within each group. The most important factors were mean fibre diameter in the Fine group, the variation in fibre diameter along the staple (SDfdalong) in the Medium group, and the variation in diameter between fibres (SDfdbetween) in the Broad group. It is concluded that SS is a complex characteristic, depending on both the fibre diameter and several sources of variation in fibre diameter, all of which can differ among flocks. Protein loss made a disproportionate contribution to liveweight loss over summer and autumn, but the amino acids made available did not contribute substantially to wool growth or SS.


1999 ◽  
Vol 50 (7) ◽  
pp. 1179 ◽  
Author(s):  
J. W. D. Cayley ◽  
G. A. Kearney ◽  
G. R. Saul ◽  
C. L. Lescun

The productivity of spring-lambing fine wool Merino sheep grazing pastures sown in 1977 to perennial ryegrass and subterranean clover was assessed from 1989 to 1998. The pastures were fertilised each autumn with single superphosphate at 6 levels, and were stocked at a low, medium, or high stocking rate (SR) at each level of fertiliser. The average phosphorus (P) applied annually since sowing (P ) ranged from 1.6 to 32.9 kg/ha. The SRs used varied with fertiliser level in that they were higher where more fertiliser had been applied, so that the highest SR at each level of fertiliser ensured that the pastures were well utilised. Each ewe raised 1 lamb, which was removed at weaning. The influence of fertiliser on the productivity of the sheep at 4 classes (1–4) of SR (mean SR = 7.1, 10.1, 12.6, and 18.2 ewes/ha for classes 1–4, respectively) was described by: y = A−BCP, where y represents production per sheep (kg), and A, B, and C are constants. For greasy fleece weight, estimates of B and C were 1.59 and 0.84; and for SR classes 1–4, the estimates of A were 5.06, 4.89, 4.78, and 4.46, respectively. For weaning weight of lambs, estimates of B and C were 8.4 and 0.82, and estimates of A were 23.5, 22.7, 21.5, and 20.9 for SR classes 1–4. The mean fibre diameter (µm) of the wool was described by: D = 14.18+1.48 GW, where GW is the mean greasy wool produced annually per sheep (kg) averaged over all sheep and years for each of the 18 treatments. The price (cents/kg) of wool with a fibre diameter D (P D) was given by: P D = 12197+4.94P2 + 688D−0.1945P20D − 5810√D, where 20 µm wool is P20 cents/kg. Supplements were fed if the body condition of ewes fell to a predetermined level. The supplement fed per ewe each year (S), expressed as metabolisable energy (in MJ) was described by: S = −602 − 44.1S R + 178.5P + 8.71S R P +539 √SR− 338.5√P−70.8P√SR, where S R and P represent the mean stocking rate (ewes/ha) and mean P applied annually. When a current set of costs and prices was applied to these equations, the maximum gross margin for a SR of 7.1 ewes/ha was $AU119/ha with 8.6 kg P/ha applied annually, and $AU262/ha for SR of 18.2 ewes/ha with 17.6 kg P/ha applied annually. If income derived from sheep is maintained constant, intensifying the sheep enterprise from the low to the high SR system would involve increasing sheep numbers by about 17%, but would release about 55% of the farm’s area for another purpose.


1996 ◽  
Vol 36 (6) ◽  
pp. 649 ◽  
Author(s):  
SC Davies ◽  
CL White ◽  
IH Williams ◽  
JG Allen ◽  
KP Croker

This paper reports the production losses resulting from treating sheep with sublethal doses of corynetoxins, the causal agent of annual ryegrass toxicity. Merino ewes were given 3 levels of corynetoxins twice weekly for 11 weeks from 26 days before the start of joining to day 51 of pregnancy, giving a cumulative dose of 0 , 0.4 or 0.8 mg/kg liveweight. The effect on ovulation, pregnancy, lamb birth weight, lamb survival and weaning weight were measured along with the liveweight and wool growth of the ewes. Corynetoxin treatment depressed (P<0.005) the activity of uridine diphospho-N-acetylglucosamine: dolichol-phosphate N-acetylglucosamine-1-phosphate transferase and liver damage was detected in ewes on the high toxin treatment (P<0.05). Ewe liveweight was unaffected by treatment but wool growth and wool fibre diameter were reduced by 10 and 7%, respectively (P<0.05). Corynetoxin treatment appeared to increase ovulation (P<0.05) and, as there was no effect on conception and embryo survival, this resulted in a 30-35% increase in the number of lambs weaned. Lamb birth weight and survival were not affected by treatment but weaning weight of the low toxin group was depressed (P<0.05). While reproduction was not adversely affected, the sheep in this trial were exposed to extremely low levels of corynetoxins which did not accumulate to levels capable of causing detectable liver damage until 23 days after joining. Even at these levels of intake, well below those required to show clinical signs (3-5 mg/kg liveweight), wool growth was reduced, suggesting that sheep grazed on mildly toxic pasture experience wool production losses in the absence of signs of the clinical disease.


1987 ◽  
Vol 109 (1) ◽  
pp. 197-199 ◽  
Author(s):  
A. J. Ash ◽  
B. W. Norton

Australian feral goats have recently been found to produce commercially viable quantities of the luxury fibre cashmere (Smith, Clarke & Turner, 1973). Cashmere is the fine down produced by secondary follicles as an undercoat during winter. Fibre diameter ranges from 8 to 24 μm with a mean diameter of 16 μm. Unlike modern breeds of sheep such as the Merino which exhibit almost continuous wool growth, cashmere growth is distinctly seasonal with fibre growth commencing in summer (long daylength) and reaching a maximum length in early winter (short daylength) (McDonald, 1985). The cashmere is cast in spring with growth recommencing again in summer.


2001 ◽  
Vol 41 (5) ◽  
pp. 611 ◽  
Author(s):  
G. J. Lee ◽  
K. J. Thornberry ◽  
A. J. Williams

An experiment was conducted to determine whether thyroxine injections would control the increases in fibre diameter when the wool growth of Merino wethers is stimulated by an increased supply of feed. Fifty-seven sheep were allocated to 1 of 5 levels of daily intake, ranging from 0.75 maintenance to ad libitum, and injected every third day with 3 mg of L-thyroxine or a saline solution (control). Sheep treated with thyroxine had elevated plasma tri-iodothyronine (T3) levels, which were highest in sheep fed the least (P<0.01). Ad libitum intakes of sheep treated with thyroxine tended to be higher than that of control sheep, particularly in the fifth to seventh weeks of the experiment, and liveweight gain over the initial 4 weeks was significantly (P<0.001) less. Wool growth was increased by thyroxine treatment, although the difference was small in the second half of the experiment at the highest intake levels. Fibre diameter of sheep treated with thyroxine was greater at low intakes, although the difference diminished as intake increased. Fibre length in the second half of the experiment was positively related to intake, but there were no effects of thyroxine. Although the relationships of fibre diameter and length with wool growth did not differ between the treatment groups, length accounted for more of the variation in wool growth in the second half of the experiment in treated wethers than in control wethers (0.376 v. 0.182 of the variation, respectively). Thyroxine did not appreciably reduce the extent of the increase in fibre diameter associated with an increase in the availability and intake of feed.


1982 ◽  
Vol 33 (5) ◽  
pp. 817 ◽  
Author(s):  
JB Hay ◽  
SC Mills

It has been shown that isotopically labelled sheep wool wax is carried passively along the wool fibre as a band by growth of the wool, and that it does not flow along the fibre to any large extent during experiments of several months. This supports the view that the function of sebum, in mammals in general, is to protect the hair (wool) fibre and the condition of the coat, and contrasts with the reported rapid spread of sebum over the human skin surface. It also seems unlikely that wax lost from the fleece during exposure to rainfall is replenished with sebum freshly secreted onto the surface, since sebum does not migrate. Two methods were used to obtain labelled wax, direct application of labelled cholesterol to the skin surface and intradermal injection of labelled sebum substrate. Prior washing of the wool with detergent showed that wax already on the fibre was not the cause of the observed lack of flow of newly formed wax. Isotopically labelled suint components were also carried passively by wool growth. It is unlikely that wax is transported to any extent by suint in the wool; this is in contrast to the suggested role of sweat in facilitating the spread of sebum over the human skin surface. Some spreading of radioactive wax and suint bands was noted however, possibly because of diffusion and mechanical disturbance of the wool.


1992 ◽  
Vol 32 (3) ◽  
pp. 267
Author(s):  
PT Doyle ◽  
RA Love ◽  
RH Dunlop ◽  
CL White

Young Merino sheep (7-8 months of age, weighing about 40.5 kg) were given weekly supplements of 1050 gfsheep of lupins, lupins coated with potassium sulfate (25 g/kg lupins), lupins and access to a mineral lick (offered at 175 g/sheep.week), or lupins coated with potassium sulfate and access to the lick. The sheep grazed an annual pasture at a stocking rate of 15 sheepha and were given the supplements between 14 December and 5 April. The amount of pasture on offer in mid December exceeded 3000 kg DMha but declined to 1500 kg DMha in late March.There were significant amounts of green feed present in December and March (>20% of pasture DM), a small amount in January, and no green feed in February. Despite this the percentage of sheep licking the minerals was over 70% in January , February; and March, with average intake being about 10 g/sheep.day. No significant differences occurred between treatments for liveweights of sheep during the feeding period or at shearing. Over the feeding period sheep lost weight at about 30 g/day. Neither the additional sulfur nor the mineral lick had any significant effects on fleece weight, mean fibre diameter of the fleece, staple length, or staple strength. Wool growth rates were not different between treatments during the feeding period. These results indicate that under good pasture conditions with some green feed available, and when lupins are supplied, responses to mineral supplements are unlikely.


1978 ◽  
Vol 90 (2) ◽  
pp. 329-334 ◽  
Author(s):  
A. A. Elsherbiny ◽  
H. A. Eloksh ◽  
A. S. Elsheikh ◽  
M. H. Khalil

SummaryWool samples were collected from 39 rams representing five breed groups of sheep: Merino (M), Ossimi (0), and the crosses between them, viz. ¾ Ossimi–¾ Merino (¾ O), ½ Ossimi–½ Merino (½ O) and ½ Ossimi–¾ Merino (¼ O) maintained at Sakha Experiment Station, Kafrelsheikh, Egypt, with the objectives of detecting the effect of the seasonal changes in normal light rhythm and temperature on wool fibre length and diameter. Animals were divided into two light treatments groups, the first consisting of four animals from each breed kept under continuous dim light conditions throughout the year and the second of three animals from Ossimi and four from each breed group kept inside an open pen free to sunlight and shade zones under daylight rhythm throughout the year. It was found that fibre length as well as fibre diameter in normal light exceeded that in dim light except in winter time. Breed groups showed different responses to the absence of light especially the Ossimi and the ¾ O whose fibre lengths were most affected. The breed groups had larger fibre diameters in normal light than in dim light except Merino and ¼ O. Seasonal changes in temperature had a highly significant effect on fibre length but not on fibre diameter. Higher temperature coincided with lower increases in fibre length. Season to season variation in wool growth seemed to suggest that the number of light hours per day and atmospheric temperature counteracted each other resulting in a non-significant seasonal pattern.


1973 ◽  
Vol 26 (2) ◽  
pp. 465 ◽  
Author(s):  
AJ Williams

Twelve mature ewes from a flock selected for high clean fleece weight (Fleece Plus) and twelve from a flock selected for low clean fleece weight (Fleece Minus) were randomly divided between two dietary treatments: 500 or 1100 g per day of chaffed lucerne hay.


1996 ◽  
Vol 47 (8) ◽  
pp. 1291 ◽  
Author(s):  
DG Masters ◽  
G Mata

Responses in wool production, ewe liveweight, lamb birth weight, and growth were compared when the major source of protein in the diet was either lupin seed or canola meal. The diets were fed to ewes during the final 3 weeks of pregnancy and first 3 weeks of lactation, and for a similar period of time to a group of dry ewes. All ewes were fed to maintain conceptus-free liveweight. The diet containing canola meal increased (P < 0.001) wool growth in the reproducing ewes (50-63%) and the dry ewes (12.5-20%) during, and for 3 weeks after, the treatment period. Fibre diameter of wool grown during the treatment period was increased (P < 0.025) by 0.5-1.5 pm in the ewes fed canola meal compared with ewes fed lupins. The ewes fed canola meal gained slightly (P = 0.06) more weight during the experiment than the ewes fed lupins. Lambs from the ewes fed canola meal were lighter (P < 0.05) at birth (480 g) than lambs from ewes fed lupins. The reproducing ewes had lower fleece weights, average fibre diameters, and staple strengths and lengths than the dry ewes. These fleece characteristics were not significantly affected by diet. Canola meal is partially protected from rumen degradation and is less expensive than other sources of similar proteins and may therefore provide a practical option for commercial sheep producers.


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