Studies on resistance of sheep to infestation with Haemonchus contortus and Trichostrongylus spp., and on the immunological reactions of sheep exposed to infestation. V. The nature of the 'self-cure' phenomenon.

1953 ◽  
Vol 4 (1) ◽  
pp. 100 ◽  
Author(s):  
DF Stewart

An experimental investigation of the nature and the mechanism of the "self-cure" phenomenon in helminthiasis of sheep has been carried out. As a result of the "self-cure" reaction there was no release of heterologous antibodies into the blood stream of the animal. The administration of an antihistamine drug usually prevented the fall in egg count which is characteristic of the "self-cure" reaction, but did not interfere with the subsequent rise in titre of the specific or homologous antibody in the serum. On 7 of 13 occasions when sheep showed the "self-cure" reaction, the blood histamine level rose to about 0.05 µg per ml. during a period of about 24 hours between the second and fourth day after the administration of larvae. On none of 13 occasions when sheep failed to manifest "self-cure" was there any rise in blood histamine. The difference in behaviour of the two groups was significant statistically. The rise in blood histamine was demonstrated when sheep infested with either H. contortus or Trichostrongylus spp. were given H. contortus larvae and manifested the "self-cure" reaction. It was shown to occur also when "self-cure" occurred in sheep infested with Trichostrongylus spp. following the administration of Trichostrongylus spp. larvae. Increase in blood histamine was not demonstrated when Trichostrongylus spp. larvae were given to seven sheen infested with H. contortus and when "self-cure" did not take place. The increase in blood histamine as not associated with any consistent alteration in the concentration of eosinophils. There was no evidence that the increase in blood histamine was the direct cause of "self-cure". Sheep which manifested "self-cure" showed a strong local reaction to the intradermal inoculation of H. contortus antigen. Continued infestation with mature H. contortus or with mature Trichostrongylus spp. did not sensitize the sheep and sheep which failed to manifest "self-cure" did not exhibit an intradermal reaction. An oedematous change was evident in the mucous membrane of the Abomasum or small intestine, depending upon the site of attachment of the adults, on the day on which a rise in blood histamine occurred after the administration of larvae. The intake of H. contortus larvae produced this change only in the abomasum of a sheep which had been infested with H. contortus and only in the small intestine of a sheep which had been infested with Trichostrongylus spp.

Author(s):  
Eva Walther ◽  
Claudia Trasselli

Abstract. Two experiments tested the hypothesis that self-evaluation can serve as a source of interpersonal attitudes. In the first study, self-evaluation was manipulated by means of false feedback. A subsequent learning phase demonstrated that the co-occurrence of the self with another individual influenced the evaluation of this previously neutral target. Whereas evaluative self-target similarity increased under conditions of negative self-evaluation, an opposite effect emerged in the positive self-evaluation group. A second study replicated these findings and showed that the difference between positive and negative self-evaluation conditions disappeared when a load manipulation was applied. The implications of self-evaluation for attitude formation processes are discussed.


2010 ◽  
Vol 55 (2) ◽  
pp. 75-86
Author(s):  
Brigitte Hilmer

Kunst kann dann als reflexiv interpretiert werden, wenn Reflexivität nicht auf propositionalen Gehalt oder sogar sprachliche Artikulation angewiesen ist. Reflexion tritt auf in den Modi der Selbstbeziehung des Lebendigen, des Überlegens und der Selbstreferenz im Symbolischen. Kunst ist ein Reflexionsmedium, das diese Modi beansprucht und miteinander verflicht. Eine spezifisch ästhetische Reflexivität ist von und nach Kant nach dem Vorbild der transzendentalen Reflexion und in Konkurrenz zu ihr etabliert worden. Sie läßt sich als Reflexivität des ästhetischen Urteils, als emphatisches Gemachtsein, als Rückwendung auf Wahrnehmungsvollzüge oder als Begriffsreflexion verstehen. Dabei wird die Unterscheidung von Anschauung und Verstand in deren Zusammenspiel oder Abspaltung vorausgesetzt. Von der Analogie zur transzendentalen Reflexion löst sich aber erst ein Verständnis von ästhetischer Reflexivität, das von den drei Modi und ihrer Verflechtung ausgeht.<br><br>Reflexivity does not presuppose linguistic articulation or even propositional content. If it did, art could not be called reflexive. Reflexivity can be found in the self-contact of the living, in mental reflection or in symbolic self-reference. Art is a medium which claims these different modes of reflexivity and intertwines them. Aesthetic reflexivity as such has been established by Kant and his epigones, following the model of transcendetal reflection. Thus it could be specified as the reflexive structure of aesthetic judgement, or as an emphasis on a work’s being created, or as a reference to perception itself in the process of perceiving, or as a way of reflecting concepts. Aesthetic reflexivity can only be detached from the model of transcendental reflection, if it is seen as oriented towards the interaction among the three modes of reflection mentioned above, leaving aside the difference, interplay or competition between perception and conceptual capacities.


1992 ◽  
Vol 262 (2) ◽  
pp. G351-G358
Author(s):  
R. Zhang ◽  
S. Barnes ◽  
R. B. Diasio

Mechanisms responsible for the difference in the relative amounts of taurine- and glycine-conjugated bile acid N-acyl amidates (Tau/Gly ratio) are not fully understood. In the present study, the stability of taurine- and glycine-conjugated bile acid N-acyl amidates during intestinal transit and absorption was examined to investigate the contribution of intestinal deconjugation to the Tau/Gly ratio in rat bile. Radiolabeled chenodeoxycholic acid (CDC) and its N-acyl amidates with glycine (CDC-Gly) or taurine (CDC-Tau) were introduced into the lumen of the upper small intestine in the biliary fistula rats, and radioactive metabolites in bile, blood, urine, and tissues were identified and quantitated by high-performance liquid chromatography. Results indicated that 1) extensive deconjugation of CDC-Gly occurs during intestinal absorption; 2) CDC-Tau is recovered in bile largely intact; and 3) newly synthesized CDC-Tau and CDC-Gly are formed in a ratio of less than 2:1 after administration of [14C]-CDC. In summary, the present study demonstrates that resistance of taurine-conjugated bile acid N-acyl amidates to hydrolysis in the intestine, rather than a difference in synthesis of taurine- and glycine-conjugated N-acyl amidates in liver, may account for the high Tau/Gly ratio in rat bile.


In their useful compendium of "Formulæ and Tables for the Calculation of Mutual and Self-Inductance," Rosa And Cohen remark upon a small discrepancy in the formulæ given by myself and by M. Wien for the self-induction of a coil of circular cross-section over which the current is uniformly distributed . With omission of n , representative of the number of windings, my formula was L = 4 πa [ log 8 a / ρ - 7/4 + ρ 2 /8 a 2 (log 8 a / ρ + 1/3) ], (1) where ρ is the radius of the section and a that of the circular axis. The first two terms were given long before by Kirchhoff. In place of the fourth term within the bracket, viz., +1/24 ρ 2 / a 2 , Wien found -·0083 ρ 2 / a 2 . In either case a correction would be necessary in practice to take account of the space occupied by the insulation. Without, so far as I see, giving a reason, Rosa and Cohen express a preference for Wien's number. The difference is of no great importance, but I have thought it worth while to repeat the calculation and I obtain the same result as in 1881. A confirmation after 30 years, and without reference to notes, is perhaps almost as good as if it were independent. I propose to exhibit the main steps of the calculation and to make extension to some related problems. The starting point is the expression given by Maxwell for the mutual induction M between two neighbouring co-axial circuits. For the present purpose this requires transformation, so as to express the inductance in terms of the situation of the elementary circuits relatively to the circular axis. In the figure, O is the centre of the circular axis, A the centre of a section B through the axis of symmetry, and the position of any point P of the section is given by polar co-ordinates relatively to A, viz.


2021 ◽  
Vol 7 (6) ◽  
pp. 6469-6476
Author(s):  
Li Qiu ◽  
Hongli Wang ◽  
Yuan Yuan ◽  
Ying Wang ◽  
Ping Yu

To analyze the effect of nursing measures based on self-efficacy theory on the state self-esteem of breast cancer patients. 110 breast cancer patients who were treated in our hospital from October 2018 to October 2019 were randomly divided into control group and observation group. The control group was given routine nursing measures, and the observation group was given nursing measures under the guidance of self-efficacy theory. Before operation, 1 week after operation and 3 months after operation, the general data of the two groups before and after treatment were recorded. The self-efficacy level and self-esteem level of the patients before and after treatment were assessed by the self-efficacy scale (GSEs) and state self-esteem scale (SSEs). The compliance of functional exercise and shoulder joint activity (ROM) of the two groups were compared, and the physical status of the two groups were analyzed. To analyze the effect of nursing measures based on self-efficacy theory on the state self-esteem of breast cancer patients. The GSEs score of the two groups increased with the time, and there was no significant difference between the two groups before operation (P > 0.05). After 1 week and 3 months, the GSEs score of the observation group was significantly higher than that of the control group (P < 0.05). The compliance evaluation table of functional exercise in the two groups increased with the time, and the compliance evaluation table of functional exercise in the observation group was significantly higher than that in the control group, the difference was statistically significant (P < 0.05). ROM of the two groups increased with time, and ROM of the observation group was significantly better than that of the control group, the difference was statistically significant (P < 0.05). The self-esteem level of the two groups increased with time, and the self-esteem level of the observation group was significantly higherthan that of the control group, the difference was statistically significant (P <0.05). The nursing measures under tne guidance of self-efficacy theory can help patients to complete functionalexercise, improve theirquality of life, improve their self-esteem level, a nd can be widely used in clinical practice.


Author(s):  
Stacey Abbott

This chapter examines the adoption and development of the first person narrative format within vampire, and more recently zombie, film and television. It considers how this trope has contributed to the rise of the sympathetic/romantic vampire figure from the Byronic hero within Polidori’s The Vampyre to Interview with the Vampire and Byzantium and the subsequent rise of the sympathetic zombie. This chapter questions if this first person point of view empties the vampire and zombie of symbolic agency, or manipulates the genre to explore new meanings. It considers how the genres of the vampire and the zombie are increasingly interconnected, moving away from themes of apocalypse and cultural anxiety to explore questions of identity and the self within a changing world, effectively queering the vampire and zombie for new audiences.Case studies include Let the Right One In, Byzantium, Only Lovers Left Alive, Warm Bodies, Colin, and In the Flesh.


The Hijaz ◽  
2018 ◽  
pp. 155-204
Author(s):  
Malik R. Dahlan

Chapter 6 is an international legal examination of the status of The Hijaz in the aftermath of its conquest and absorption into a Saudi personal union. It discusses the impact of the 1933 Montevideo Convention on the Rights and Duties of States as well as the Territorial Principle. The Chapter tackles the legal question of secession and warns against the pitfalls of the ‘Self-Determination Trap’. It draws lessons from the difference between involuntary extinction of states as opposed to their creation. By looking at the cases of Czechoslovakia and Quebec it tackles the issue of ‘the Right to Secession by Agreement’. The Chapter reflects on lessons from Scotland, Catalan and Kurdistan highlighting that The Hijaz presents us with a delicate and nuanced understanding of ‘Internal Self-Determination’ and ‘Autonomy’ establishing, de facto, an international legal status of “Self-Determination Spectrum Disorder”. A special status calls for an active and special legal solution. The notion of a broader integrative role for The Hijaz and the broader Islamic world. The potential integrative institutionalization of The Hijaz is investigated bringing to bare a unique approach to self-determination that would entail coupling autonomy with international territorial administration. The propositions under this Chapter are supported by looking at other sui generis entities such as the Holy See being sovereigns without being states.


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