Metabolic and production responses to different porcine somatotropin injection regimes in pigs

2002 ◽  
Vol 53 (7) ◽  
pp. 785 ◽  
Author(s):  
F. R. Dunshea

Thirty-two female crossbred pigs (initial weight 75 kg) were used in this experiment to investigate the effect of differing porcine somatotropin (pST) regimes on growth performance. Pigs were kept in individual pens and fed ad libitum a wheat-based diet formulated to contain 14.4 MJ DE/kg and 180 g ideal protein/kg. Treatments were daily injection with saline (Sal), daily injection with pST (5 mg) (D), bi-daily injection with pST (10 mg) (2D), and injection with pST (12 mg) every Monday, Wednesday, and Friday (MWF). On the days that pigs were not receiving pST they were injected with saline (0.5 mL). All pST regimes caused a reduction (P < 0.001) in feed intake and feed conversion ratio (FCR), although there was no significant effect on average daily gain. Feed intake decreased after the first injection and, for the D group, remained low and constant. Feed intake for the 2D group was also reduced but not to as great an extent as for the D group. Feed intake in the MWF group showed a clear temporal response, being low during the week but increasing over the latter part of the weekend. Thus, feed intake from Sunday until Monday mornings was 400 g greater (P < 0.001) than from Saturday until Sunday mornings. Therefore, it appears that the effects of pST on feed intake may be reduced when a 3-day interval is used between injections. Back fat was significantly reduced with all pST injection regimes, whereas estimated fat deposition was only significantly reduced in the D and 2D pigs. Plasma urea nitrogen was increased, whereas glucose was decreased during pST administration and the average concentrations of both metabolites during the first week of administration were strongly related (P < 0.001) to FCR over the full 3 weeks of the study (R = 0.733 and -0.683, respectively). Although daily injection with pST appears to give the greatest reduction in feed intake and fat deposition, an alternative pST injection regime involving less frequent pST injections can also improve growth performance similarly in finisher pigs.

2003 ◽  
Vol 54 (1) ◽  
pp. 11 ◽  
Author(s):  
I. McCauley ◽  
M. Watt ◽  
D. Suster ◽  
D. J. Kerton ◽  
W. T. Oliver ◽  
...  

The use of a vaccine (Improvac) directed against gonadotrophin-releasing factor (GnRF), to prevent boar taint in male pigs, is also associated with an increase in feed consumption, growth, and higher deposition of subcutaneous fat. Daily administration of porcine somatotropin (pST) consistently increases average daily gain, and feed conversion efficiency, and reduces subcutaneous fat, particularly in gilts. The objective of this study was to examine the effect of combining these treatments in boars and gilts. Forty-eight pigs (Large White × Landrace), housed individually, were used in a 2 × 2 × 2 factorial experiment with the respective factors being vaccination with GnRF vaccine (at 14 and 18 weeks of age), daily injection with pST (from 18 weeks to slaughter at 22 weeks), and sex (boars and gilts). Performance was measured over the period of pST administration. Over the entire 28 days of the study, daily gain was lower for gilts than for boars (1216 v. 1410 g/day, P < 0.001), was increased by pST (1219 v. 1407 g/day, P < 0.001), but not significantly altered by vaccination against GnRF (1284 v. 1342 g/day, P = 0.15). However, GnRF vaccination increased daily gain in the second 2 weeks of the study, and overall, there were interactions such that the vaccine increased gain in all groups except boars not receiving pST. Feed intake over the study period was less for gilts than for boars (3139 v. 3407 g/day, P < 0.001), was decreased by pST (3537 v. 3009 g/day, P < 0.001), and increased by vaccination against GnRF (3139 v. 3407 g/day, P < 0.001). When averaged over the entire study, feed conversion ratio (FCR) was higher for gilts than for boars (2.76 v. 2.51, P = 0.013), was decreased by pST (3.05 v. 2.22, P < 0.001), but unchanged by vaccination against GnRF (2.62 v. 2.65, P = 0.70). Fat deposition was lower in gilts than in boars (335 v. 378 g/day, P = 0.037), was decreased by pST treatment ((442 v. 271 g/day, P < 0.001), and increased by vaccination against GnRF (333 v. 379 g/day, P = 0.026). In boars, fat androstenone was reduced by vaccination against GnRF (0.10 v. 2.47 μg/g, P < 0.001) and tended to be reduced by pST (1.71 v. 2.44, P = 0.10), but only vaccination against GnRF reduced skatole (0.174 v. 0.050 μg/g, P < 0.001). The combination of the treatments in all cases was at least additive, and in some cases synergistic. The concomitant vaccination against GnRF and treatment with pST affords an opportunity to increase growth rate and feed intake above control levels and above those of pigs treated with either treatment alone.


2002 ◽  
Vol 53 (3) ◽  
pp. 287 ◽  
Author(s):  
F. R. Dunshea ◽  
M. L. Cox ◽  
M. R. Borg ◽  
M. N. Sillence ◽  
D. R. Harris

Porcine somatotropin (pST) treatment of pigs consistently improves average daily gain (ADG) and feed conversion ratio (FCR). However, most studies have been conducted with individually housed pigs, of unimproved genotype and over a lighter finisher phase than current practice. The present study was designed to determine whether a commercial pST (Reporcin) treatment regime would improve growth performance in heavy boars and gilts (initial weight 79 kg) of an improved genotype and housed under commercial conditions. The 2 2 factorial experiment involved 160, 19-week-old Large White Landrace pigs (80 males and 80 females) in 20 pens of 8 pigs/pen. The respective factors were sex (boars and gilts) and dose of pST (0 and 5 mg/day). Pigs were fed a wheat-based diet formulated to contain 200 g crude protein, 10.2 g available lysine, and 14.6 MJ DE/kg to ensure that responses to pST and sex were expressed. Injections of pST were given daily for 28 days prior to slaughter using a commercial applicator designed for this purpose. Pigs were bled by venipuncture on days 7 and 28 of treatment and the plasma samples analysed for plasma urea nitrogen (PUN) and glucose. The degree of stomach ulceration at slaughter was assessed by a veterinary pathologist. Daily pST treatment increased ADG (P = 0.003), particularly in gilts, as indicated by the interaction (P = 0.015) between sex and pST. Thus, gilts treated with pST grew 23% faster than control gilts (1093 v. 1273 g/day), whereas the pST-treated boars grew only slightly faster (+2.5%) than control boars (1261 v. 1291 g/day). Feed intake was similar for boars and gilts and was decreased in both sexes by 10% during pST treatment. FCR was higher in control gilts than in boars and was improved by pST treatment. This was particularly evident in the gilts such that there was no difference in the FCR of pST-treated gilts and boars. Back fat at slaughter was reduced by 2.3 and 3.2 mm in boars and gilts treated with pST, respectively. The only stomach lesions observed were very minor in severity and there was no effect of pST on the proportion of pigs exhibiting stomach ulcers (7/80 and 9/79 for control and pST-treated pigs, respectively; χ2 = 0.31, P = 0.58) or visible possible injection site lesions (0/80 and 1/79; χ2 = 1.01, P = 0.31). The PUN response mirrored the effects of sex and pST on FCR. Indeed, there was a high correlation (R = +0.84, P < 0.001) between FCR and PUN. In conclusion, pST treatment of finisher pigs of an improved genotype and housed under simulated commercial conditions improved growth performance, decreased back fat, and negated sex differences.


2018 ◽  
Vol 58 (11) ◽  
pp. 2100 ◽  
Author(s):  
Don V. Nguyen ◽  
Bunmi S. Malau-Aduli ◽  
Peter D. Nichols ◽  
Aduli E. O. Malau-Aduli

The objective of this study was to investigate the effects of enriched omega-3 oil supplemental pellets, breed and gender on lamb liveweight (LWT), body conformation and carcass characteristics, and to assess the relationships between body conformation and growth under an intensive finishing condition. Sixty ewe and wether prime lambs 7 months old were randomly allocated to one of five dietary treatments: no oil inclusion (Control); 2.5% canola oil; 5% canola oil; 2.5% flaxseed oil and 5% flaxseed oil, balanced by breed (purebred Merinos (M × M) and Corriedale × Merino (C × M) and White Suffolk × Corriedale (W × C) first crosses). Lambs were individually supplemented with 1 kg pellets per day and had free access to lucerne hay and water throughout the 7-week feeding trial, after a 3-week adaptation. Dietary oil inclusion did not cause significant differences in daily feed intake, growth performance and carcass characteristics (P > 0.05). However, first-cross W × C lambs had significantly higher feed intake, chest girth and body conformation score (P < 0.05) than M × M and C × M lambs. Carcass weight, dressing percentage and fat depth of crossbred lambs were significantly higher than those of M × M (P < 0.05). Significant interactions between oil inclusion and breed on average daily gain (ADG) and feed conversion ratio were observed. There were positive and highly significant correlations among LWT, ADG and body conformation measurements (P < 0.01). These findings suggest that prime lamb producers can better manage and match their breeding goals with feed resources by supplementing first-cross C × M lambs with pellets containing 5% canola oil or feeding first-cross W × C lambs with 5% flaxseed oil pellets during the 10-week intensive finishing period.


2021 ◽  
Author(s):  
Maggy Palesa Mabena ◽  
Moses Ratsaka ◽  
Thobela Nkukwana ◽  
Ingrid Malebana ◽  
Douglas Nkosi

Abstract This experiment evaluated varying levels of Amarula (Sclerocarya birrea A. Rich) nut cake (ANC) on growth performance, nutrient digestibility and carcass characteristics in pigs. Thirty Large White × Landrace (LW × LR) pigs were stratified by weight (average live weight of 20 ± 5 kg) and randomly allocated to the five experimental diets that contained 0 (control), 50, 100, 150 and 200 g ANC/kg DM. Each pig served as a replicate unit, housed individually. Bodyweight, feed intake, average daily gain (ADG) and feed conversion ratio (FCR) were recorded weekly throughout the trial period. On completion of the growth trial, following a 3-day adaptation, a nutrient digestibility study was conducted over 5 days. Thereafter, pigs were fasted for twelve hours, weighed, slaughtered, and carcass samples were collected for analysis. Feed intake was not affected by dietary treatment, but ADGs were reduced at ANC levels > 15%, resulting in poor FCR. Protein digestibility was reduced at ANC levels > 15%, while ether extract and fibre levels increased. Warm and cold carcass weights were lower at ANC levels > 15, with improved meat redness and lightness. It was concluded that ANC could replace SBM in the diet of growing pigs at less than 15% inclusion level.


Author(s):  
MM Rahman ◽  
NR Sarker ◽  
MA Alam

This study was carried out to evaluate the feeding effect of high yielding fodders (HYF) on feed intake and growth performance of growing Hilly Brown Bengal (HBB) goat. For this purpose, a feeding trail was conducted with 16 growing HBB kids (4 to 5 months) by dividing equally in four groups having four replicates for a period of 75 days. The goats in group T0 (control) received natural grass along with 101.30g concentrates and adlibitum cowpea hay, whereas in group T1, T2 and T3, only natural grass was replaced by BLRI Napier 3, BLRI Napier 4 and Ruzi fodder, respectively. Total dry matter intake (DMI), roughages DMI, crude protein intake (CP), body weight gain (kg), average daily gain (g) and forth night body weight gain (g/day) were studied. Results revealed that, DMI (288.39, 285.71, 293.48 and 301.35 g/day in group T0, T1, T2 and T3, respectively), body weight gain (3.60, 3.74, 3.73 and 3.77 kg in group T0, T1, T2 and T3, respectively), average daily gain (47.32, 49.16, 49.12 and 48.92 g in group T0, T1, T2 and T3, respectively) and feed conversion ratio (6.2, 5.9, 6.0 and 6.1 in group T0, T1, T2 and T3, respectively) of HBB kids were not differed significantly (P>0.05) for all the treatment groups. The DMI from roughages (196.2, 193.5, 201.3 and 209.2 g/day in group T0, T1, T2 and T3, respectively) and CP intake (38.7, 42.1, 48.3 and 38.8 g/day in group T0, T1, T2 and T3, respectively) were significantly varied (P<0.05), while highest CP intake was found in the treatment group T2. Forthnight body weight (g/day) was not significantly (P>0.05) gained with feeding of HYF for all the treatment groups. From this study, it can be concluded that, growing HBB kids could equally be supplied with either BLRI Napier 3 or BLRI Napier 4 or Ruzi fodder in addition to ad libitum cowpea hay for better voluntary feed intake and growth. Bang. J. Livs. Res. Vol. 27 (1&2), 2020: P. 73-81


Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2181
Author(s):  
Silvia Martínez-Miró ◽  
Josefa Madrid ◽  
Miguel José López ◽  
Juan Orengo ◽  
Cristian Jesús Sánchez ◽  
...  

A total of 192 Iberian × Duroc pigs kept under intensive conditions were used to investigate the effects of feeding crude glycerin on growth performance, nutrient digestibility, and blood parameters. Animals were blocked by initial body weight (96.0 ± 11.3 kg) and allotted to pens (16 pigs per pen). Pens were assigned randomly to one of three dietary treatments (four pens per treatment). Dietary treatments contained 0, 5, or 10% of crude glycerin proportionally substituting for wheat (G0, G5, and G10, respectively). Diets were formulated to be isoenergetic and isoaminoacidic. No significant effect of crude glycerin was observed on average daily gain, average feed intake, or feed conversion ratio. The apparent total tract digestibility of dry matter, organic matter, and crude protein was no different between treatments. Total serum protein, albumin, glucose, insulin, and IGF-1 were not affected by glycerin inclusion. In conclusion, crude glycerin up to 100 g/kg can be included in the diets of finishing Iberian crossbred pigs without any negative effect on growth performance, digestibility, or serum metabolic parameters.


1970 ◽  
Vol 46 (3) ◽  
pp. 294-301
Author(s):  
K.H. Kim ◽  
E.S. Cho ◽  
K.S. Kim ◽  
J.E. Kim ◽  
K.H. Seol ◽  
...  

Effects of stocking density on growth performance, carcass grade and immunity of pigs housed in sawdust fermentative pigstiesThis study determined the effect of space allowance on performance, carcass grade and physiological variables of pigs reared in sawdust fermentative pigsties. A total of 699 crossbred (Landrace × Yorkshire × Duroc) pigs were housed in sawdust fermentative pigsties and assigned to one of three treatments at different growth stages, namely early grower pigs (EGP), weighing 15 - 40 kg; late grower pigs (LGP), weighing 40 - 75 kg; and finisher pigs (FP), weighing 75 - 110 kg, with three replicates. The three space allowances for each growth stage were 0.40, 0.55 and 0.70 m2/head for EGP; 0.55, 0.70 and 0.85 m2/head for LGP; and 0.85, 1.00 and 1.15 m2/head for FP. The feed intake in EGP was significantly decreased with increased stocking density. In LGP, the average daily gain (ADG) of pigs reared at high stocking density decreased linearly, whereas the feed conversion ratio increased significantly. The final bodyweight, ADG and feed intake in FP were lower with restricting space allowance. The carcass weight and backfat thickness were significantly higher with increased space allowance. The serum immunoglobulin G levels declined significantly with increased stocking density in all growth stages. The results of this study suggest that the space allowance for maximizing the growth performance and stabilizing immune response of pigs in sawdust fermentative pigsties is 0.55, 0.70, and 1.00 m2/pig for the bodyweight ranges of 15 - 40 kg, 40 - 75 kg, and 75 - 110 kg, respectively.


Author(s):  
Masiza Samuel Mikasi ◽  
Joseph Jimu Baloyi ◽  
Everson Bhebe

This experiment was conducted to evaluate the effects of supplementing 10% or 15% of baobab seed cake (BSC) or macadamia oil cake (MOC) in fattening diets for lambs on feed intake, growth performance and carcass characteristics. Thirty-two lambs aged between 150 and 180 days were randomly allocated to 4 diets (10% MOC; 15% MOC; 10% BSC and 15% BSC diets) in an experiment arranged as a 2x2 factorial design and sex as a block. The results showed that there were significant protein source and inclusion level interactions on average daily feed intake, average daily gain, and total weight gain, warm and cold carcass mass. Males were significantly superior in all parameters except for feed conversion ratio, dressing percentage and rib-eye area. It was concluded that 10% MOC and 15% BSC can be incorporated in diets for fattening of growing South African Mutton Merino lambs without compromising on their growth performance and carcass characteristics.


Author(s):  
Woong B Kwon ◽  
Jose A Soto ◽  
Hans H Stein

Abstract An experiment was conducted to test the hypothesis that increased dietary Trp is needed in high-Leu diets for growing pigs to prevent a drop in plasma serotonin and hypothalamic serotonin concentrations and to maintain growth performance of animals. A total of 144 growing pigs (initial weight: 28.2 ± 1.9 kg) were assigned to 9 treatments in a randomized complete block design with 2 blocks, 2 pigs per pen, and 8 replicate pens per treatment. The 9 diets were formulated in a 3 × 3 factorial with 3 levels of dietary Leu (101, 200, or 299% standardized ileal digestible [SID] Leu:Lys), and 3 levels of dietary Trp (18, 23, or 28% SID Trp:Lys). A basal diet that met requirements for SID Leu and SID Trp was formulated and 8 additional diets were formulated by adding crystalline L-Leu and (or) L-Trp to the basal diet. Individual pig weights were recorded at the beginning of the experiment and at the conclusion of the 21-d experiment. On the last day of the experiment, one pig per pen was sacrificed, and blood and hypothalamus samples were collected to measure plasma urea N, plasma serotonin, and hypothalamic serotonin concentrations. Results indicated that increasing dietary Trp increased (P &lt; 0.05) hypothalamic serotonin, whereas increases (P &lt; 0.05) in average daily gain (ADG) and average daily feed intake (ADFI) were observed only in pigs fed diets containing excess Leu. Increasing dietary Leu reduced (P &lt; 0.05) ADG, ADFI, and hypothalamic serotonin. However, the increase in ADG and ADFI caused by dietary Trp was greater if 299% SID Leu:Lys was provided than if 101% SID Leu:Lys was provided (interaction, P &lt; 0.05). Plasma Leu concentration was positively affected by dietary Leu and negatively affected by dietary Trp, but the negative effect of Trp was greater if 299% SID Leu:Lys was provided than if 101% SID Leu:Lys was provided (interaction, P &lt; 0.05). Plasma concentration of Trp was positively affected by increased dietary Trp and increased dietary Leu, but the increase in plasma concentration of Trp was greater if Leu level was at 101 % SID Leu:Lys ratio than at 299% SID Leu:Lys ratio (interaction, P &lt; 0.05). In conclusion, increased dietary Leu reduced ADG, ADFI, and hypothalamic serotonin concentration, and influenced metabolism of several indispensable amino acids, but Trp supplementation partly overcame the negative effect of excess Leu. This demonstrates the importance of Trp in regulation of hypothalamic serotonin, and therefore, feed intake of pigs.


2019 ◽  
Vol 3 (4) ◽  
pp. 1162-1172
Author(s):  
Tassilo Brand ◽  
Martin Hünerberg ◽  
Tim A McAllister ◽  
Maolong He ◽  
Atef M Saleem ◽  
...  

Abstact: The purpose of this study was to evaluate the effect of a phytogenic feed additive (Digestarom [DA]; Biomin, Getzersdorf, Austria) on growth performance, feed intake, carcass traits, fatty acid composition, and liver abscesses of finishing steers. One hundred twenty Angus × Charolais crossbred steers (488 ± 26.5 kg) were used in a 110-d feeding experiment. Steers were blocked by weight and randomly assigned to 12 pens with 10 steers per pen. Each pen was allocated to one of three diets. Each diet contained 86.5% barley, 10.0% barley silage, and 3.5% vitamin and mineral supplement on a dry matter (DM) basis. The diets contained 0, 0.05, and 0.1 g DA/kg complete diet (DM basis), to achieve average daily DA intakes of 0 (control), 0.5 (LowDA), and 1.0 g (HighDA) per steer. Diets were prepared once daily and provided ad libitum. Two pens per treatment were equipped to record individual feed intake behavior. Steers were weighed every 28 d and carcass traits and liver scores were recorded at slaughter. Dry matter intake (average: 9.34 kg/d) did not differ (P &gt; 0.05) among diets. Average daily gain tended to increase linearly as DA increased (control: 1.82; LowDA: 1.87; and HighDA: 1.95 kg/d; P &lt; 0.09), but gain:feed ratio was not affected. Supplementation of DA affected longissimus muscle area quadratically (P = 0.05) with the largest area observed for LowDA. However, dressing percentage decreased linearly in response to increasing level of DA (P &lt; 0.01). Total abscessed livers were not affected, whereas proportion of severe liver abscesses was numerically lower with DA (30.8% and 42.5% for LowDA and HighDA) compared to the control (50%).


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