Do triclabendazole medicated molasses blocks have a role in control of Fasciola gigantica in smallholder cattle production in Lao PDR?

2019 ◽  
Vol 59 (4) ◽  
pp. 787 ◽  
Author(s):  
P. A. Windsor ◽  
S. Nampanya ◽  
B. Kinnavong ◽  
P. Phommasone ◽  
R. D. Bush ◽  
...  

Smallholder cattle production in many developing tropical countries including Laos is compromised by widespread endoparasitism, with limited farmer knowledge of parasites and facilities for administration of therapeutics. We report a pilot study examining the potential for triclabendazole provided in medicated molasses blocks offered to control Fasciola gigantica in smallholder cattle production. This study involved 241 cattle allocated into three groups: (1) triclabendazole (as Fasinex®, Novartis Animal Health Australia, Pty Ltd) medicated molasses blocks (MMB) with each tonne of MMB containing 0.5 kg triclabendazole; (2) unmedicated molasses blocks; and (3) a Control group. Data and faecal samples were obtained at Weeks 1, 4, 8 and 12 for faecal egg counts (FEC) determination. Reductions in FEC in the MMB group of 90.48% and a mean FEC of 4 ± 17 eggs per gram of faeces at 12 weeks post-treatment was observed, with liveweight increasing from 174.60 (±3.35) kg to 191.50 (±3.69) kg in Weeks 1 and 12, respectively (P = 001) and an average daily weight gain of 201 g/day. Reduction in FEC in the unmedicated molasses blocks group was also observed, by 28.78% and 18.96%, with liveweight increasing from 179.50 (±3.35) kg to 189.90 (±6.05) kg in Weeks 1 and 12 respectively (P = 0.3), with an average daily gain of 124 g/day. This study suggests that productivity was enhanced when triclabendazole was added to the blocks, delivering parasite suppression or potentially therapeutic doses on ad libitum feeding of the MMB. Although further work is required to establish the therapeutic potential of MMB, the use of MMB may offer a parasite management and nutritional supplementation strategy for smallholder farmers, particularly in Laos and other countries where unmanaged Fasciola spp. infestations reduce ruminant productivity and facilities for animal restraint to enable delivery of oral anthelmintics, are largely non-existent.

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 452-453
Author(s):  
Daniel Mendoza-Cortés ◽  
Jorge L Ramos-Méndez ◽  
Adrián Félix-Bernal ◽  
Alfredo Estrada-Angulo ◽  
Manuel Franco ◽  
...  

Abstract Ninety young crossbreed bulls (approximately 25% Zebu breeding with the remainder represented by continental and British breeds in various proportions, initial weight=228.04±7.06 kg) were used in a 84-day feeding trial to assess the effects of treatments in feedlot cattle fed transition diets during high ambient temperatures. Treatments consisted of a steam-flaked corn-based diets (average 1.95 Mcal ENm/kg) supplemented with: 1) 20 mg monensin/kg diet (MON, Rumensin, Elanco Animal Health, Indianapolis, IN], and 2) 100 mg of blend of essential oils /kg diet plus 0.1 mg 25-hydroxy-vitamin-D3/kg diet (EO+HyD; CRINA® Ruminants and HyD®, DSM Nutritional Products, Basel, Switzerland). Both dry matter intake (DMI) and climatic variables were measured daily and the temperature humidity index (THI) was estimated. Daily maximal THI remained over 80 during the whole trial (avg. THI = 82.67). Cattle supplemented with EO+HyD increased average daily gain in 8.7% (1.446 vs. 1.320 kg/day, P < 0.01), gain-to-fed ratio in 4.5% (0.199 vs. 0.190; P = 0.03), final weight in 10.05 kg (349.48 vs. 339.43; P = 0.04) and tended (P = 0.07) to shown greater dietary net energy (2.5%) and observed-to-expected dietary NE ratio (3%). Even when EO+HyD tended to increase (4.3%; P = 0.06) DM intake, intake pattern variation were not different (P = 0.38) between MON and EO+HyD (Figure 1). Then, difference in ADG and final BW between MON and EO+HyD was not only a reflection of difference in energy intake, was also caused by difference in efficiency of energy utilization during conditions of high ambient temperature (a reduction of 7% in the estimated increase of coefficient of maintenance by heat load). Results indicate that supplementation with a combination of essential oil blend plus 25-hydroxy-vitamin-D3 can have greater beneficial effects than supplemental monensin on daily weight gain, final weight and feed intake during initiation-transition phase of cattle raised under high ambient temperature.


2014 ◽  
Author(s):  
Ai Thanda Kyaw

The World Organisation for Animal Health (OIE) Sub-Regional Representation for South East Asia (OIE SRR-SEA) implemented the Stop Transboundary Animal Diseases and Zoonoses (STANDZ) Programme funded by AusAID to strengthen the veterinary services and effectively manage the control and eradication of foot and mouth disease (FMD) in Cambodia, Lao PDR and Myanmar. The purpose of the study is to understand how FMD outbreaks impact smallholder farmers, both men and women, at the household and village level and how control and eradication of FMD would benefit them. Specific aims are to estimate the direct and indirect socio-economic costs associated with the outbreaks of FMD as well as of the measures taken by farmers to deal with such outbreaks and to identify issues that contributed to the socio-economic impacts of FMD outbreaks and opportunities to reduce them.


2021 ◽  
Vol 6 (1) ◽  
pp. 57-63
Author(s):  
Galina Molyanova ◽  
Maksim Nogotkov

The purpose of the research is increasing the average daily gain of animals due to the use of the Bisolbi drug. The effect of Bisolbi preparation based on Bacillus subtilis H-13 1.5×108 (LLC «Bisolbi-Inter») on the biochemical and productive life of calves was studied. The scientific and production experiment was carried out on the basis of a dairy farm of the State «Kupinskoe» Unitary Enterprise of the Samara region involving 30 Holstein-Friesian calves. The biological effect of the drug is provided due to its adsorption properties, the ability to enhance the activity of a number of enzyme systems and increase the digestive and systemic immunity of the body. The drug use increases the integration intensity of animals: the amount of total protein in the blood serum of calves of the experimental group at 120 days of age was higher by 8.9% (p<0.05), albumin – by 9.2% (p<0.01), compared with the animal data of con-trolled group. The Bisolbi indication contributed to an increase in the intensity of carbohydrate-lipoid metabolism: the cholesterol amount was higher by 23% (p<0.01), the glucose content – by 0.4 mmol/l (p<0.05) in the blood of 120 day old calves of the experimental group, compared with the data of controlled animals. It was found that the body weight of calves in the control group of 100 days age was 105.23±2.11 kg, in the experimental group – 108.6±2.19 kg, which is 3.37 kg higher. The average daily weight gain of animals in experimental group was signif-icantly higher by 0.075 kg (p<0.01). At 120 days of age, the body weight of the experimental calves was higher by 4.19 kg (p<0.05), the average daily weight gain by 0.080 kg (p<0.05), compared with the data of the controlled ani-mals. The indication of Bisolbi 5-10 ml (LLC «Bisolbi-Inter») to calves daily for 2 months resulted in an additional profit constructively of 137 rubles from each head.


Author(s):  
Vangroenweghe F ◽  

Background: Post-Weaning Diarrhoea (PWD) in pigs is a worldwide economically important disease, which is frequently controlled using antimicrobials. However, emergence of antimicrobial resistance in E. coli strains and new EU regulations urge the need for alternative control measures, such as adapted feeding strategies or immunization. Oral vaccination of suckling piglets using a live non-pathogenic E. coli F4/F18 vaccine was performed in 10 farrow-to-finish sow farms to prevent against post-weaning diarrhoea due to F4-Enterotoxigenic E. coli (ETEC) or F18-ETEC. The vaccination strategy was compared to the standard therapeutic approach in each farm, meanwhile collecting data on Average Daily Weight Gain (ADWG), Feed Conversion Rate (FCR), mortality rate and treatment incidence with antimicrobial drugs (TI100) during the post-weaning period. Results: Vaccine-treated groups demonstrated a significant improvement in FCR, mortality rate and TI100 as compared to the Control group. The ADWG only marginally and non-significantly improved in the Vaccine-treated group. Conclusions: In conclusion, the present study demonstrated the efficacy of an oral live non-pathogenic E. coli F4/F18 vaccine (Coliprotec® F4/F8; Elanco Animal Health) for active immunization of piglets against PWD due to F4-ETEC and F18-ETEC under field conditions. For several economically important performance parameters, such as FCR, mortality rate and TI100, E. coli vaccination performed significantly better as compared to the standard therapeutic approach. Therefore, vaccination against PWD due to F4-ETEC or F18-ETEC using an oral live non-pathogenic E. coli F4/F18 vaccinated may be considered a good alternative to consolidate post-weaning piglet performance results while meeting the new European requirements concerning prudent use of antimicrobials in intensive pig production.


Author(s):  
V. S. Bomko ◽  
◽  
M. S. Zakharchuk ◽  
O. M. Tytariova ◽  
◽  
...  

Aimed to study the effective use of different doses of cuprum proteinate in the diet of broiler chickens, three groups of animals were formed with 50 chicks in each. Chickens from the 1st control group received cuprum sulphate as a part of compound feed, and animals from the 2nd and 3rd experimental groups received cuprum proteinate. The concentration of Cuprum in the feed in the 1st and 2nd groups was identical, and in the 3rd experimental group the amount of Cuprum was reduced by 25% compared to the control. During scientific and economic experiment, it was found that the replacement of cuprum sulphate with its proteinate with the same concentration in the feed has a positive effect on the average daily gain of broiler chickens, and therefore a live weight. Thus, the animals from the 2nd experimental group exceeded control analogues by 7.5% in average daily gain and by 9.4% in body mass at the end of the experiment. Reducing the concentration of Cuprum in the feed of chickens from the 3rd experimental group by 25% (the source of the microelement is cuprum proteinate) compared to the control also had a positive effect on the productivity of these animals. They exceeded control analogues in terms of average daily weight gain by 3.8%, and in terms of live weight by 5.8%. At the same time the direct correlation between animal productivity and quantity of the consumed feed was noted. Thus, broilers from the 2nd experimental group consumed more feed by 3.3% compared to control peers. The chickens from the 3rd experimental group exceeded controls by 1.5% in this index. Thus, cuprum proteinate is a more efficient source of Cuprum for broiler feed. The concentration of this microelement in the feed of these animals aged 5-21 days should be 18.2 g/t, 22–35 days - 16.8 g/t, 36–42 days - 12 g/t or 16.5 g/t on average during the experiment.


2019 ◽  
Vol 59 (10) ◽  
pp. 1847
Author(s):  
Gessica Perin ◽  
Matheus D. Baldissera ◽  
Matheus Fernandes ◽  
Mauricio Barreta ◽  
Renata A. Casagrande ◽  
...  

The emergence of antibiotic-resistant bacteria in the intestinal microbiota of broiler chickens, and the possibility of antibiotic residues in meat and meat products are seen as a threat to animal and human health. The search for alternatives to conventional drugs, including natural compounds, is an interesting approach to prevent the adverse effects of antibiotics. Therefore, the aim of the present study was to evaluate whether the addition of tannin (as a quebracho extract) in the diet of broiler chickens could be used to replace in-feed antimicrobials and coccidiostatic drugs, to exert positive effects on animal health and performance. The use of tannin in the diet of broiler chicks as an additive (at 0.5% for 1–10-day-old birds; and 1.0% for 11–42-day-old broiler chickens) enhanced their bodyweight, weight gain and daily weight gain on Day 42 of life, compared with the untreated control group (P &lt; 0.05). However, these findings were not observed when tannin was added at 0.5%. Moreover, broiler chickens fed with an extract containing tannins showed higher erythrocyte counts, as well as haemoglobin and haematocrit concentrations than did those in the control group, whereas counts of total leukocytes and lymphocytes were lower (P &lt; 0.05). The use of a diet with tannins did not influence meat quality compared with a diet containing zinc bacitracin and salinomycin, which altered some parameters associated with meat colour. Moreover, the diet with tannins reduced (P &lt; 0.05) the number of oocysts of Eimeria sp. (36-day-old broilers) and the total faecal bacterial counts (42-day-old broilers) compared with the control group. Finally, intestinal histopathology showed that the addition of tannins minimised the degree of lesions (Degree 1) compared with the control group (Degree 3). On the basis of these results, we concluded that the use of quebracho extract containing tannins can be a suitable approach to improve the performance of broiler chickens, replacing in-feed antibiotics and coccidiostatic drugs. The use of tannins did not change meat quality; however, it caused positive effects on the immune system, and exerted potent bactericidal and coccidiostatic properties, reinforcing its use as a replacement for conventional drugs.


2014 ◽  
Vol 54 (5) ◽  
pp. 629 ◽  
Author(s):  
J. R. Young ◽  
L. Rast ◽  
S. Suon ◽  
R. D. Bush ◽  
L. A. Henry ◽  
...  

Future food security has become a major global concern and is particularly important in the Greater Mekong Subregion where several countries have seen rapid urban economic development and increasing demand for red meat. In Cambodia, the majority of livestock producers are subsistence or semi-subsistence rural smallholder farmers using cattle as a source of protein, fertiliser, draught power, and asset storage. Potential income from smallholder cattle is limited by a range of factors that compromise productivity, including endemic diseases, poor nutrition, and lack of knowledge of husbandry techniques and marketing practices. To address the developing opportunities to improve rural incomes from cattle production in Cambodia, a 4-year longitudinal study was conducted to examine ‘best practice’ interventions that could improve productivity and profitability of cattle within smallholder farming systems. The study involved six villages from three provinces, with two villages in each of the provinces of Takeo, Kandal and Kampong Cham paired and designated as either high intervention (HI) or low intervention (LI). A best practice intervention program was introduced to the HI villages to develop the husbandry skills of farmers, including implementation of forage technology, disease prevention through vaccination for foot-and-mouth disease and haemorrhagic septicaemia, deworming, and education in nutrition, biosecurity, disease control, and marketing. Between April 2008 and February 2012, eight repeat-measures capturing data on animal health and production, including cattle weights used to evaluate the impact of interventions on average daily gains, were completed. Cattle in HI villages had significantly (P < 0.01) higher mean liveweight during the last three sampling periods, and average daily gains were 2.4 times higher than in cattle of the LI villages. This study provides evidence that best practice interventions resulted in improved cattle productivity, farmer knowledge and positive impacts on household income over time, offering a pathway that can address food security concerns and more rapidly alleviate rural poverty in the GMS.


2014 ◽  
Vol 54 (7) ◽  
pp. 899 ◽  
Author(s):  
S. Nampanya ◽  
S. Khounsy ◽  
L. Rast ◽  
J. R. Young ◽  
R. D. Bush ◽  
...  

Applied participatory research on large-ruminant health and production was conducted in six villages in northern Lao PDR. Three villages were classified as ‘high intervention’ (HI) and the remaining three as ‘low intervention’ (LI) sites, with a suite of health and productivity interventions implemented in the HI sites enabling comparison of outcomes with the LI sites, where only a vaccination program was introduced. A 3-year longitudinal study to establish baseline production variables, including liveweight, average daily weight gain (ADG) and reproductive performance, was conducted. The study involved 1500 head of cattle and buffalo that were ear-tagged and weighed every 3–4 months between 2008 and 2011, producing 10 data-collection points. Significant differences in ADG of the cattle between the provinces (P < 0.001), but not between HI and LI villages (P = 0.39), was observed. Low calving rates (51–75% and 41–52%) and inter-calving intervals (13.6–15.7 and 18.6–20.6 months) for cattle and buffalo, respectively, were observed. An on-farm large ruminant-fattening trial (n = 44) was conducted over a 4-month period to examine differences in productivity between cut-and-carry stall fattening (n = 26) and free-grazing (n = 18) systems. Cattle and buffalo in fattening stalls (320 and 217 g/day) had significantly greater ADG than those free-grazing (40 and 85 g/day) (P < 0.001 and P = 0.001). The increase in sale value for fattened cattle and buffalo was US$78 and US$123, respectively. The longitudinal study indicated that if risks of important diseases such as foot and mouth disease and haemorrhagic septicaemia are controlled by vaccination and biosecurity, improved productivity outcomes in northern Lao PDR can be achieved by establishing forage plantations to better manage variations in seasonal availability of feed and enabling fattening. We conclude that improved large-ruminant productivity, by improving health and nutrition practices, offers opportunities for smallholder farmers to increase livestock income, alleviate rural poverty and improve regional food security in South-east Asia.


2019 ◽  
Vol 32 (2) ◽  
pp. 115-125 ◽  
Author(s):  
Emad A. Dhari ◽  
Waleed Y. Kassim

The study was established to evaluate the effect of adding selenium with or without vitamin E on some of productive and physiological characteristics of Awassi male lambs. Sixteen lambs were selected after weaning with average weight of 24.30 kg and 3-4 months. All lambs fed 2% of body weight with basal diet and 1 kg green alfalfa /Lamb/day. The lambs were randomly divided into 4 groups. Control group (no additives), Selenium group (0.4 mg selenium), Vitamin group (100 mg vitamin E) and selenium + vitamin E group (0.4 mg selenium + 100 mg vitamin E) per kg dietary dry matter for 90 days. At the end of experiment, lamb performance and concentrations of Thyroxin T4, insulin and growth hormone were measured. The result showed that selenium and the combination of selenium + vitamin E treatments significantly increased (p <0.05) growth rates, final live body weight 42.20, 41.75 kg, respectively, and average daily gain 195, 191 g/day, respectively compared to other treatments. A significantly increase (P <0.05) in the concentrations of thyroxin hormone (T4) recorded in selenium + vitamin E treatment 18.20 ng/ml compared to selenium treatment and vitamin treatment. A significantly increase (P <0.05) in the concentrations of growth hormone of selenium treatment which recorded 9.279 ng/ml compared to vitamin treatment and control group. There is no difference in insulin hormone concentration between the groups. So we conclude that the addition of selenium with or without vitamin E to lamb diets achieved significant improvement in final body weight, daily weight gain, thyroxin and growth hormone.


Author(s):  
S. Grikshas ◽  
N. Kulmakova ◽  
K. Spitsyna ◽  
A. Dar’in ◽  
T. Mittelshtein

Mycotoxins have been formed in feed are secondary metabolites of fungi and are quite stable substances that have teratogenic, mutagenic and carcinogenic effects. An effective way to combat mycotoxins in feed is the use of feed additives that adsorb toxins, prevent their absorption in the gastrointestinal tract of the animal and are excreted from the body. The infl uence of coconut enterosorbent Shelltic Es on fattening and meat qualities of young pigs has been studied. It has been found in the process of fattening that the highest feed digestibility was in pigs of the experimental group, in the diet of which enterosorbent has been added. The results of studies of the chemical composition and technological properties of pork have been provided. The positive eff ect of enterosorbent on precocity, absolute average daily gain of live weight and reduction of feed expenditures per 1 kg of gain has been revealed. In pigs from the experimental group the average thickness of the fat was higher and the area of the “muscle eye” was lower compared with animals of the control group, which indicates that higher rates of carcass yield have been obtained due to faster accumulation of fat tissue. The weight of internal organs of pigs indicates the intensity of metabolic processes in the body. In experimental animals the weight of the lungs was 0,1 kg lower, and the liver and heart were higher by 0,13 and 0,01 kg, respectively. Enterosorbent had no effect on the content of vitamins in the liver of pigs of the compared groups. The content of impurities of organochlorine toxicants and toxic elements in the meat and liver of animals of the experimental group was lower than that of control analogues. Therefore, the use of enterosorbent Shelltic Es promotes more active excretion of them from the body.


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