Antimicrobial drug usage and poultry production: case study in Ghana

2019 ◽  
Vol 59 (1) ◽  
pp. 177 ◽  
Author(s):  
Sherry Johnson ◽  
Kwasi Bugyei ◽  
Priscillia Nortey ◽  
William Tasiame

Antimicrobial use in food animal production could lead to the occurrence of antimicrobial residues in the animal products. In Ghana, there is no monitoring program for antimicrobial residue in foods of animal origin. We determined the types of antimicrobial drugs used in poultry production in Dormaa municipality and the levels of residue found in poultry products. Performing a cross-sectional study, a structured questionnaire and direct observation methods were used to assess antimicrobial usage, knowledge of and adherence to withdrawal periods in randomly selected poultry farms. Eggs and ready-for-sale broilers were purchased from selected respondents’ farms for detection and quantification of residues using the microbial inhibition plate assay. A total of 132 farmers were interviewed from 115 farms. Farms (86%) administered drugs to birds for prophylactic purposes. A total of 28 (24.3%) farms had tetracycline residue in eggs, 25 (21.7%) in kidney and 14 (12.2%) in liver. Mean (±s.d.) tetracycline concentration (μg/g) found were: eggs 0.02 ± 0.003; kidneys 0.02 ± 0.01; and liver 0.01 ± 0.008. Twenty-six farms (92.9%; ρ > 0.05) that had residues in eggs had sold eggs during treatment of the laying birds. A disinfectant and two antibiotics in human formulations were administered to birds in 44.3%, 17.4% and 2.6% farms respectively on an extra-label basis. Tetracyclines were the main antimicrobial drugs used in poultry farming in the study area with little or no regard to withdrawal periods. Tetracycline residue was found in poultry but below the Maximum Residue Level set by Codex Alimentarius. Extra-label use of disinfectant to water-medicate birds poses a health hazard to farmers and consumers alike.

Author(s):  
Mohamed A. Baraka ◽  
Lina Hussain AlLehaibi ◽  
Hind Nasser AlSuwaidan ◽  
Duaa Alsulaiman ◽  
Md. Ashraful Islam ◽  
...  

Abstract Background Antimicrobial agents are among the most commonly prescribed drugs in pregnancy due to the increased susceptibility to infections during pregnancy. Antimicrobials can contribute to different maternal complications. Therefore, it is important to study their patterns in prescription and utilization. The data regarding this issue is scarce in Saudi Arabia. Therefore, the aim of this study is to generate data on the antimicrobial agents that are most commonly prescribed during pregnancy as well as their indications and safety. Methods This is a retrospective study focusing on pregnant women with a known antimicrobial use at Johns Hopkins Aramco Healthcare (JHAH). The sample included 344 pregnant women with a total of 688 antimicrobial agents prescribed. Data was collected on the proportion of pregnant women who received antimicrobial agents and on the drug safety during pregnancy using the risk categorization system of the U.S. Food and Drug Administration (FDA). Results The results showed that urinary tract infections (UTIs) were the most reported (59%) infectious diseases. Around 48% of pregnant women received antimicrobial medications at some point during pregnancy. The top two antimicrobial agents based on prescription frequency were B-lactams (44.6%) and azole anti-fungals (30%). The prescribed drugs in the study were found to be from classes B, C and D under the FDA risk classification system. Conclusion The study revealed a high proportion of antimicrobials prescribed during pregnancy that might pose risks to mothers and their fetuses. Future multicenter studies are warranted to evaluate the rational prescription of antimicrobial medications during pregnancy.


2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Sarah A. S. Dodd ◽  
Cate Dewey ◽  
Deep Khosa ◽  
Adronie Verbrugghe

Abstract Background Cats, being obligate carnivores, have unique dietary requirements for nutrients most commonly found in dietary ingredients of animal origin. As such, feeding a diet devoid of animal-derived ingredients has been postulated as a possible cause of nutrient imbalances and adverse health outcomes. A small proportion of cat owners feed strictly plant-based diets to the cats in their care, yet the health and wellness of cats fed these diets has not been well documented. Results A total of 1325 questionnaires were complete enough for inclusion. The only exclusion criterion was failure to answer all questions. Most cats, 65% (667/1026), represented in the survey were fed a meat-based diet and 18.2% (187/1026) were fed a plant-based diet, with the rest fed either a combination of plant-based with meat-based (69/1026, 6.7%) or indeterminable (103/1026, 10%). Cat age ranged from 4 months to 23 years, with a median of 7 years, and was not associated with diet type. No differences in reported lifespan were detected between diet types. Fewer cats fed plant-based diets reported to have gastrointestinal and hepatic disorders. Cats fed plant-based diets were reported to have more ideal body condition scores than cats fed a meat-based diet. More owners of cats fed plant-based diets reported their cat to be in very good health. Conclusions Cat owner perception of the health and wellness of cats does not appear to be adversely affected by being fed a plant-based diet. Contrary to expectations, owners perceived no body system or disorder to be at particular risk when feeding a plant-based diet to cats. This study collected information from cat owners and is subject to bias, as well as methodological limitations. Further research is warranted to determine if these results are replicable in a prospective investigation.


2020 ◽  
Author(s):  
Rehab A. Rayan

For improving accomplished attempts to stop smoking, it is necessary to learn about the qualities of individuals who can willingly stop smoking. This study seeks to discover the willingness degree and associated determinants to stop smoking between adult visitors of a primary healthcare centre in an urban area of Alexandria in Egypt. In this single point and descriptive cross-sectional study, a semi-structured questionnaire was distributed to a sample of 53 adults aged ≥18 years in May 2019. Descriptive statistical analyses were conducted to evaluate the determinants influencing the willingness to stop smoking. Of the 53 respondents (with a mean age of 38.7 years old), 41.5% of them were males. Almost 18.9% of the respondents were ongoing smokers (36.4% of males and 6.5% of females), though 83.7% of those smokers were willing to stop smoking. The number of male smokers was significantly greater than female smokers (Pearson Chi-Square = 7.52, p-value = 0.006). Determinants, which can favourably influence the willingness to stop smoking, were believing that smoking is a health risk to them (100%) and the others around (94.3%). A bulk of participants (56.6%) doubted the need for nicotine supplements to help in smoking cessation. Smoker respondents were willing to stop smoking. Understanding that smoking is a health hazard for both smokers and the others around can motivate smoking cessation. Relying on nicotine supplements alone might not add favourably to a strong smoking cessation decision. Tailoring campaigns to raise awareness about smoking health hazards’ would support and sustain smoking cessation.


Author(s):  
Mahesh Kumar Choudary ◽  
Manmohan Gupta ◽  
Rachit Saxena ◽  
Sandeep Kumar Uppadhaya

Background: Hepatitis B virus (HBV) is a double-stranded circular DNA virus and member of the Hepadnaviridae family of viruses. Methods: This cross sectional study was done on 250 nursing staff. There were total 263 nursing staff in this hospital out of which 250 enrolled voluntarily to participate in this study. The objective, nature and benefits of this study were explained and informed & written consent was taken from all participants. All nursing staff were interviewed structured self-completed quaternaries. Results: Hepatitis B virus (HBV) infection is an occupational health hazard preventable by vaccination. 78% of nursing staff know that Hep B is a vaccine preventable. 42% of participants knew that getting vaccinated offers a protection from infection for 15 years.  16% of nursing staff are aware that a titre value of more than 10 ml U/ml is needed for protection from Hepatitis B infection. 84% of nursing staff are willing to motivate others and encourage them to get vaccinated against Hepatitis B. Conclusion: This study highlighted the need to have nursing staff educated regarding significance of immunization against vaccine preventable disease. Keywords- Hepatitis, Immunization, Liver,


2021 ◽  
Vol 11 (6) ◽  
pp. 14-20
Author(s):  
Nisar Ahmed ◽  
Mohanta GP ◽  
Bhagat MP

The antimicrobial resistance has more impact on the health care division which would increase the mortality and hospital readmission duration. Our objective is to assess the community pharmacist’s knowledge on dispensing of antimicrobial drugs and prevention of antimicrobial resistance in community practice. A cross-sectional study was conducted for six months. A sample size of 150 registered community pharmacists participated in the study. We have used simple random techniques to select the community pharmacists. Questionnaire were distributed to the community pharmacists at pre and post visits and the response was analyzed. The collected data was analyzed using graph pad prism software. The mean and standard deviation was calculated and P<0.005 was considered to be statistically significant. For 25-30 years of age , community pharmacists were more 68 (45.33%) as compared to other ages. Pre visit before and after average mean antimicrobial resistance score was found to be 4.87. Proper implementation of antimicrobial resistance prevention programmes would drastically increases the rational use of antimicrobials could and minimizes the health care cost.


2015 ◽  
Vol 5 (2) ◽  
pp. 336-338 ◽  
Author(s):  
Shila Rani Das ◽  
Nasreen Begum ◽  
Chinmay Biswas ◽  
Md Nazmul Hoq ◽  
Jahangir Hossain

Background: Taking protective equipment is important for poultry workers as they are at risk of poultry hazard. Use of personal protective equipment (PPE) is essential for preventing & controlling diseases experienced by poultry processing workers.Aims and Objectives: To assess the awareness about personal protective equipments and health problems among poultry workers.Method and materials: Descriptive cross-sectional study was conducted under the guidance of the Department of Community Medicine, National Institute of Preventive and Social Medicine (NIPSOM), Dhaka, from March to June 2006 on 100 poultry workers who were selected purposively from six poultry farms from the area of Gazipur districts. Informed consent was obtained and structured questionnaire was used to collect data through face to face interview. Data was edited, processed and analyzed both manually and used of SPSS version 10.Result: Mean age was 27.49% with SD ± 9.84 years, highest age range 59% was 20-30 years. Regarding level of education & economic status revealed that 43% were illiterate and 72% earned 2000-3000 taka monthly. 20% had highest work experience of 6-8 years. 82% of the respondents thought that personal protection is necessary during working in poultry. 79% of the respondents knew the name of PPE. But only 42% use PPE and 58% of the respondents did not use it. Among the user 16% use PPE regularly and 26% use PPE irregularly. Result showed significant association between education and knowledge of diseases of transmission (p<0.004). Observing health hazard 34.71% had respiratory problem 27.27% skin problem 23.14% eye problem. Significant association found between itching (skin problem) and use of PPE (p<0.004).Conclusion : Literate person had more knowledge about disease transmissions. The respondents who used PPE suffered less from health problems. For the safety of poultry workers advocacy arrangements of training program and formulation of guideline and regulations are important points to be considered.Northern International Medical College Journal Vol.5(2) 2014: 336-338


2014 ◽  
Vol 9 (1) ◽  
pp. 19-24
Author(s):  
MR Alam ◽  
MA Wahab ◽  
MM Rahman ◽  
AKM Asaduzzaman ◽  
MAS Al-Azad ◽  
...  

Introduction: Noise Induced Hearing Loss (NIHL) is an occupational health hazard linked with noise exposure of more than 85 dB. Aircraft noise and other occupational noise exposure cause military aviators more susceptible to NIHL than commercial jet pilots. Aim: To find out the prevalence of noise induced hearing loss among different military aircrew population with special emphasis on identifying the associated risk factors. Materials and Methods: This cross sectional study was conducted on Kuwait Air force pilots those who came for annual medical checkup from July 2010 to July 2012. Audiometry of all subjects was done by ENT specialist and necessary data were collected by structured questionnaires. All data were analyzed by SPSS (Statistical Package for the Social Sciences) version 17.0 Results: Out of 221 aircrew 32 (14.48%) developed NIHL. Hearing loss was mild to moderate and predominately at high frequencies. Most affected group was helicopter pilots. Pilots of more than 40 years of age and those who had more than 1000 flying hours had mean hearing threshold more than other groups. The right ear was affected in majority of cases than left ear. Conclusion: Noise exposure to aircrew is inevitable so hearing loss prevention strategies might play a pivotal role to save aircrew hearing. Active surveillance of hearing protection practices might have beneficiary effect. Steps can be taken for early detection of NIHL and hearing conservation program. DOI: http://dx.doi.org/10.3329/jafmc.v9i1.18721 Journal of Armed Forces Medical College Bangladesh Vol.9(1) 2013: 19-24


2004 ◽  
Vol 7 (3) ◽  
pp. 467-472 ◽  
Author(s):  
Annika Waldmann ◽  
Jochen W Koschizke ◽  
Claus Leitzmann ◽  
Andreas Hahn

AbstractObjective:The study aimed to evaluate the homocysteine and cobalamin status of German vegans and determine whether the intake of very small amounts of foods of animal origin can improve this status.Design and setting:Cross-sectional study, Germany.Subjects:The dietary and nutritional intakes of 131 vegans (73 women, 58 men; a range: 20.2–82.1 years) were evaluated using a general questionnaire and two food–frequency questionnaires.Results:The prevalence of inadequate cobalamin status in volunteers of the German Vegan Study was 28.2%, and that of hyperhomocysteinaemia, 38.1%. Moderate vegans were affected to a lesser extent than were strict vegans. Duration of veganism and cobalamin concentration were inversely correlated (Spearman'sr= -0.175,P= 0.047). Folate concentration and erythrocyte aspartic acid aminotransferase activity were not correlated with plasma homocysteine concentration, but duration of veganism correlated positively with homocysteine concentration (Spearman'sr= 0.319,P< 0.001). Cobalamin and homocysteine concentrations were inversely correlated (when controlling for duration of veganism;r= -0.602,P< 0.001).Conclusion:Cobalamin status needs to be improved in order to minimise the risk of hyperhomocysteinaemia.


Author(s):  
Zuhura I. Kimera ◽  
Robinson H. Mdegela ◽  
Consolatha J.N. Mhaiki ◽  
Esron D. Karimuribo ◽  
Faith Mabiki ◽  
...  

Oxytetracycline is used to treat various diseases in cattle. However, its use may be associated with unacceptable residue levels in food. Oxytetracycline residues in tissues from indigenous cattle were determined in a cross-sectional study conducted in the Kilosa district, Tanzania, between November 2012 and April 2013. A total of 60 tissue samples, including muscle, liver and kidney, were collected from slaughterhouses and butchers and analysed for oxytetracycline using high-performance liquid chromatography. Oxytetracycline residues were found in 71.1% of the samples, of which 68.3% were above acceptable regulatory levels. The mean concentration of oxytetracycline across tissues was 3401.1 μg/kg ± 879.3 μg/kg; concentrations in muscle, liver and kidney were 2604.1 μg/kg ± 703.7 μg/kg, 3434.4 μg/kg ± 606.4 μg/kg and 3533.1 μg/kg ± 803.6 μg/kg, respectively. High levels of oxytetracycline residue in meat from indigenous cattle may pose a health threat to consumers in Kilosa. The findings possibly reflect a general lack of implementation of recommended withdrawal periods, ignorance about drug use and lack of extension services. Strict regulation of the use of antimicrobial drugs in the livestock industry and associated testing of animal-derived food sources prior to marketing are required.


2021 ◽  
Vol 14 ◽  
pp. 1-12
Author(s):  
Mohd Shahrol Abd Wahil ◽  
Sharifah Fazlinda Syed Nor ◽  
Wong Chin Mun ◽  
Norain Ahmad ◽  
Noor Dalila Inche Zainal Abidin ◽  
...  

This study primarily intends to determine visitors’ perception of leptospirosis health hazard warning signage and its effectiveness within natural recreational parks in the district of Hulu Langat. This cross-sectional study was conducted in four out of seven natural recreational parks, installed with leptospirosis health hazard warning signage. A total of 209 respondents were recruited purposively in this study and completed the questionnaires. Majority of the respondents were male (57.4%), 40 years old and below (89.5%), received tertiary education (68.5%), staying outside Hulu Langat district (83.2%), visited for the first time (63.6%), and noticed the presence of leptospirosis health hazard warning signage at the park entrance (69.4%) and within the recreational park (64.2%). A significant relationship was discovered between respondents’ education level and perception of the health hazard warning signage (p-value 0.034). The rate of visits and noticeability of the health hazard warning signage were significantly associated with the effectiveness of the content on the health hazard warning signage (p-value 0.002 and 0.004, respectively). The construction of health hazard warning signage at the recreational areas should suit the social and educational background of the population. Visitors’ discernment of the effectiveness of erecting leptospirosis health hazard warning signage within natural recreational parks in the district of Hulu Langat is good if the signage is perceptible even with subsequent repeated visits to the parks.


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