Improved Beat Asynchrony Detection in Early Blind Individuals

Perception ◽  
10.1068/p7789 ◽  
2014 ◽  
Vol 43 (10) ◽  
pp. 1083-1096 ◽  
Author(s):  
Elodie Lerens ◽  
Rodrigo Araneda ◽  
Laurent Renier ◽  
Anne G De Volder
Keyword(s):  
Asynchrony Detection ◽  
Blind Individuals

Nonphotic entrainment of the human circadian pacemaker

1998 ◽  
Vol 274 (4) ◽  
pp. R991-R996 ◽  
Author(s):  
Elizabeth B. Klerman ◽  
David W. Rimmer ◽  
Derk-Jan Dijk ◽  
Richard E. Kronauer ◽  
Joseph F. Rizzo ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
Light Exposure ◽  
Core Body Temperature ◽  
Biological Clock ◽  
Bright Light ◽  
Circadian Pacemaker ◽  
Temperature Rhythms ◽  
Blind Individuals ◽  
Nonphotic Entrainment ◽  
Core Body

In organisms as diverse as single-celled algae and humans, light is the primary stimulus mediating entrainment of the circadian biological clock. Reports that some totally blind individuals appear entrained to the 24-h day have suggested that nonphotic stimuli may also be effective circadian synchronizers in humans, although the nonphotic stimuli are probably comparatively weak synchronizers, because the circadian rhythms of many totally blind individuals “free run” even when they maintain a 24-h activity-rest schedule. To investigate entrainment by nonphotic synchronizers, we studied the endogenous circadian melatonin and core body temperature rhythms of 15 totally blind subjects who lacked conscious light perception and exhibited no suppression of plasma melatonin in response to ocular bright-light exposure. Nine of these fifteen blind individuals were able to maintain synchronization to the 24-h day, albeit often at an atypical phase angle of entrainment. Nonphotic stimuli also synchronized the endogenous circadian rhythms of a totally blind individual to a non-24-h schedule while living in constant near darkness. We conclude that nonphotic stimuli can entrain the human circadian pacemaker in some individuals lacking ocular circadian photoreception.

Web-ALAP: A Web-based LaTeX Editor for Blind Individuals

2020 ◽  
Author(s):  
Safa Arooj ◽  
Shaban Zulfiqar ◽  
Muhammad Qasim Hunain ◽  
Suleman Shahid ◽  
Asim Karim
Keyword(s):  
Web Based ◽  
Blind Individuals

Kurzweil Reading Machine: Evaluation of Model One

1978 ◽  
Vol 72 (10) ◽  
pp. 415-418
Author(s):  
Lawrence A. Scadden
Keyword(s):  
Comprehensive Evaluation ◽  
Evaluation Process ◽  
Tactile Display ◽  
Final Report ◽  
Work Related ◽  
Reading Material ◽  
Stage Of Development ◽  
Early Fall ◽  
Blind Individuals ◽  
Evaluation Project

In summary, the evaluation of the KRM has demonstrated that this approach and this specific machine can permit immediate access to printed material by most blind individuals. The greatest limitation at this stage of development is related to the confidence level that many users have placed in the ability of the machine to read various kinds of reading material. This factor has limited the use of the machine as an aid to employment of blind people. It is believed that many of the problems identified in the evaluation process can be overcome with further research and development of the KRM. The evaluation of the KRM by blind and sighted individuals throughout the country has led to the unanimous conclusion that further investigations with improved models of the KRM are warranted. The software in the existing models should be improved to eliminate some of the problems identified above. Hardware changes should be made to eliminate other identified problems. The concern regarding the lack of use of the KRM by employed blind individuals residing close to existing machines probably cannot be alleviated until reading machines of this kind can be located within the actual employment situation. Blind individuals are not willing, nor should they be, to travel to where machines are located in order to read work related materials. Other alternatives, including sighted readers, can be utilized within a work setting. This conclusion suggests the necessity of reaching the point at which speech-output reading machines can be affordable by individuals. Postscript: Since the completion of this evaluation project and the submission of the final report to the supporting governmental agency and to the manufacturer, KCP announced plans for Model Three of the KRM, a desk-top unit. The design includes most of the recommendations suggested in this report such as a hand-scanning option, a small tactile display to assist in format recognition, automatic contrast control with manual override capability, and a spell-next-letter feature. In addition, KCP announced several innovative features. The new model will permit the improved speech synthesizer to speak at rates up to 250 words per minute. Model Three will also have the capability of attaching to a braille embosser to provide direct print to braille conversion. The unit can also be attached to a computer to provide immediate full vocabulary output for computers. A new program is being developed to be used with all KRM's to permit the reading machines to be used as high-powered, programmable, scientific calculators. The new models and programs are scheduled for distribution in early fall 1978. Comprehensive evaluation of these advances is planned.

scholarly journals Occipital Cortex of Blind Individuals Is Functionally Coupled with Executive Control Areas of Frontal Cortex

2015 ◽  
Vol 27 (8) ◽  
pp. 1633-1647 ◽  
Author(s):  
Ben Deen ◽  
Rebecca Saxe ◽  
Marina Bedny
Keyword(s):  
Working Memory ◽  
Functional Connectivity ◽  
Sentence Comprehension ◽  
Memory Load ◽  
Memory Task ◽  
Occipital Cortex ◽  
Memory Systems ◽  
Functional Responses ◽  
Congenitally Blind ◽  
Blind Individuals

In congenital blindness, the occipital cortex responds to a range of nonvisual inputs, including tactile, auditory, and linguistic stimuli. Are these changes in functional responses to stimuli accompanied by altered interactions with nonvisual functional networks? To answer this question, we introduce a data-driven method that searches across cortex for functional connectivity differences across groups. Replicating prior work, we find increased fronto-occipital functional connectivity in congenitally blind relative to blindfolded sighted participants. We demonstrate that this heightened connectivity extends over most of occipital cortex but is specific to a subset of regions in the inferior, dorsal, and medial frontal lobe. To assess the functional profile of these frontal areas, we used an n-back working memory task and a sentence comprehension task. We find that, among prefrontal areas with overconnectivity to occipital cortex, one left inferior frontal region responds to language over music. By contrast, the majority of these regions responded to working memory load but not language. These results suggest that in blindness occipital cortex interacts more with working memory systems and raise new questions about the function and mechanism of occipital plasticity.

scholarly journals Spatial navigation by congenitally blind individuals

2015 ◽  
Vol 7 (1) ◽  
pp. 37-58 ◽  
Author(s):  
Victor R. Schinazi ◽  
Tyler Thrash ◽  
Daniel-Robert Chebat
Keyword(s):  
Spatial Navigation ◽  
Congenitally Blind ◽  
Blind Individuals

scholarly journals Auditory speed processing in sighted and blind individuals

2021 ◽  
Vol 21 (9) ◽  
pp. 2519
Author(s):  
Giorgia Bertonati ◽  
Maria Bianca Amadeo ◽  
Claudio Campus ◽  
Monica Gori
Keyword(s):  
Blind Individuals
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