Comparison of Fundus Autofluorescence and Minimum-Motion Measurements of Macular Pigment Distribution Profiles Derived from Identical Retinal Areas

Perception ◽  
10.1068/p5196 ◽  
2005 ◽  
Vol 34 (8) ◽  
pp. 1029-1034 ◽  
Author(s):  
Anthony G Robson ◽  
Glen Harding ◽  
Frederik J G M van Kuijk ◽  
Daniel Pauleikhoff ◽  
Graham E Holder ◽  
...  
Keyword(s):  
Optical Density ◽  
Linear Correlation ◽  
Fundus Autofluorescence ◽  
Macular Pigment ◽  
Scanning Laser Ophthalmoscope ◽  
Grey Scale ◽  
Circular Field ◽  
Density Values ◽  
Pigment Distribution ◽  
Motion Measurements

The optical density of macular pigment was measured at twelve retinal locations in ten subjects by minimum motion photometry, comparing 460 nm with 580 nm or 550 nm. Fundus autofluorescence images were obtained for the same subjects with a scanning laser ophthalmoscope. Optical density was computed from mean calibrated grey-scale values for a central circular field and for annular segments, identical to areas tested psychophysically, and for complete annuli. Psychophysical assessments of optical density were similar irrespective of whether 550 nm or 580 nm was used. Optical density values derived psychophysically showed a linear correlation with assessments based on identical sampled areas of annular segments (slope = 0.98, r2 = 0.97) or complete annuli (slope = 0.89, r2 = 0.96) in autofluorescence images.

scholarly journals Two-wavelength fundus autofluorescence and macular pigment optical density imaging in diabetic macular oedema

Eye ◽  
2012 ◽  
Vol 26 (8) ◽  
pp. 1078-1085 ◽  
Author(s):  
S M Waldstein ◽  
D Hickey ◽  
I Mahmud ◽  
C A Kiire ◽  
P Charbel Issa ◽  
...  
Keyword(s):  
Optical Density ◽  
Macular Oedema ◽  
Fundus Autofluorescence ◽  
Diabetic Macular Oedema ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

The role of the macular pigment optical density measurement in the diagnosis of eye diseases

2016 ◽  
Vol 16 (4) ◽  
pp. 197-200
Author(s):  
E.N. Eskina ◽  
◽  
E.A. Egorov ◽  
A.V. Belogurova ◽  
А.А. Gvetadze ◽  
...  
Keyword(s):  
Optical Density ◽  
Density Measurement ◽  
Macular Pigment ◽  
Eye Diseases ◽  
Macular Pigment Optical Density ◽  
Optical Density Measurement

scholarly journals Macular Pigment Optical Density and Photoreceptor Outer Segment Length as Predisease Biomarkers for Age-Related Macular Degeneration

2020 ◽  
Vol 9 (5) ◽  
pp. 1347 ◽  
Author(s):  
Norihiro Nagai ◽  
Sakiko Minami ◽  
Misa Suzuki ◽  
Hajime Shinoda ◽  
Toshihide Kurihara ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Optical Density ◽  
Outer Segment ◽  
Macular Pigment ◽  
Age Related Macular Degeneration ◽  
Segment Length ◽  
Macular Pigment Optical Density ◽  
Photoreceptor Outer Segment ◽  
Age Related ◽  
Fellow Eyes

To explore predisease biomarkers, which may help screen for the risk of age-related macular degeneration (AMD) at very early stages, macular pigment optical density (MPOD) and photoreceptor outer segment (PROS) length were analyzed. Thirty late AMD fellow eyes, which are at high risk and represent the predisease condition of AMD, were evaluated and compared with 30 age-matched control eyes without retinal diseases; there was no early AMD involvement in the AMD fellow eyes. MPOD was measured using MPS2® (M.E. Technica Co. Ltd., Tokyo, Japan), and PROS length was measured based on optical coherence tomography images. MPOD levels and PROS length in the AMD fellow eyes were significantly lower and shorter, respectively, than in control eyes. MPOD and PROS length were positively correlated in control eyes (R = 0.386; p = 0.035) but not in AMD fellow eyes. Twenty (67%) AMD fellow eyes met the criteria of MPOD < 0.65 and/or PROS length < 35 μm, while only five (17%) control eyes did. After adjusting for age and sex, AMD fellow eyes more frequently satisfied the definition (p < 0.001; 95% confidence interval, 3.50–60.4; odds ratio, 14.6). The combination of MPOD and PROS length may be a useful biomarker for screening predisease AMD patients, although further studies are required in this regard.

scholarly journals Macular pigment optical density in central serous chorioretinopathy

2021 ◽  
Vol 13 ◽  
pp. 251584142199719
Author(s):  
Burcu Polat Gultekin ◽  
Esra Sahli
Keyword(s):  
Confidence Interval ◽  
Optical Density ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Macular Pigment ◽  
Central Retinal Thickness ◽  
Macular Pigment Optical Density ◽  
Chronic Central Serous Chorioretinopathy ◽  
Acute Central Serous Chorioretinopathy

Purpose: The aim of our study was to evaluate the macular pigment optical density in patients with acute and chronic central serous chorioretinopathy and to describe the association between central retinal thickness and choroidal thickness with the macular pigment optical density. Materials and Methods: Eyes with acute central serous chorioretinopathy and chronic central serous chorioretinopathy (patients, who were diagnosed as having disease activity for 6 months) were included in this study. Macular pigment was measured using the heterochromatic flicker technique of the MPS II device for both eyes in patients with acute and chronic central serous chorioretinopathy and in control subjects. Results: Twenty-seven eyes with acute central serous chorioretinopathy, 23 eyes with chronic central serous chorioretinopathy, and 25 control eyes were enrolled. The mean macular pigment optical density in chronic central serous chorioretinopathy (0.480 ± 0.16 density unit (95% confidence interval: 0.390–0.570) was found to be significantly lower than in the control eyes (0.571 ± 0.128 density unit) (95% confidence interval: 0.480–0.670) ( p = 0.007). In correlation analysis, no significant association was detected between the central retinal thickness, choroidal thickness, and macular pigment optical density values in central serous chorioretinopathy group ( p = 0.31, p = 0.71). Conclusion: Macular pigment optical density levels were significantly lower in chronic central serous chorioretinopathy patients than in controls, possibly due to degeneration of the neurosensorial retina, as a result of the long-term persistence of subretinal fluid. There was not a significant correlation between choroidal thickness and macular pigment optical density levels in central serous chorioretinopathy group.

Macular pigment optical density in aging eye

2013 ◽  
Vol 251 (12) ◽  
pp. 2831-2832
Author(s):  
Lin Miao ◽  
Zhen-Yong Zhang ◽  
Zhi-Qiang Yu ◽  
Chong-Da Chen
Keyword(s):  
Optical Density ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

Light Exposure and Macular Pigment Optical Density

2003 ◽  
Vol 44 (1) ◽  
pp. 306 ◽  
Author(s):  
Adam J. Wenzel ◽  
Kenneth Fuld ◽  
James M. Stringham
Keyword(s):  
Optical Density ◽  
Light Exposure ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

scholarly journals Relationships of Macular Pigment Optical Density With Plasma Lutein, Zeaxanthin, and Diet in an Elderly Population: The Montrachet Study

2016 ◽  
Vol 57 (3) ◽  
pp. 1160 ◽  
Author(s):  
Seydou Alassane ◽  
Christine Binquet ◽  
Vanessa Cottet ◽  
Olivier Fleck ◽  
Niyazi Acar ◽  
...  
Keyword(s):  
Optical Density ◽  
Elderly Population ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

scholarly journals Study of Homogeneity and Water Absorption Behavior of Double Layer Silver Gray Tiles Using Film Neutron Radiography Technique

1970 ◽  
Vol 43 (2) ◽  
pp. 197-206
Author(s):  
MK Alam ◽  
MN Islam ◽  
MA Zaman
Keyword(s):  
Water Absorption ◽  
Double Layer ◽  
Optical Density ◽  
Immersion Time ◽  
Building Materials ◽  
Neutron Radiography ◽  
Radiographic Image ◽  
Radiographic Images ◽  
Building Products ◽  
Density Values

Neutron radiography (NR) technique has been adopted to study homogeneity and water absorption behavior of building materials, like double layer silver gray tiles obtained from Concord Real Estate & Building Products, Unit II, Salna, Gazipur, Dhaka, Bangladesh. Measurements of optical density differences between the film background and radiographic images of the dry/wet samples were used for investigation of the present work. The optical density was measured by using the digital optical densitometer (Model 07-424, S-23285, Victoreen Inc. USA). Large variation in optical density values of the radiographic image was observed. From this observation it shows that the rate of water absorption of the tiles increases with increase of immersion time. Through the investigation of radiographic image and subsequently analyzing the optical density we observed that distribution of the elements in the tiles are inhomogeneous. Key words: Homogeneity, Water absorption, Silver gray, Neturon radiography.DOI: 10.3329/bjsir.v43i2.963 Bangladesh J. Sci. Ind. Res. 43(2), 197-206, 2008

Macular pigment optical density at four retinal loci during 120 days of lutein supplementation

2007 ◽  
Vol 27 (4) ◽  
pp. 329-335 ◽  
Author(s):  
Adam J. Wenzel ◽  
Joseph P. Sheehan ◽  
Catherine Gerweck ◽  
James M. Stringham ◽  
Kenneth Fuld ◽  
...  
Keyword(s):  
Optical Density ◽  
Macular Pigment ◽  
Macular Pigment Optical Density
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