A new therapeutic approach in medullary thyroid cancer treatment: Inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant

Surgery ◽  
2002 ◽  
Vol 132 (6) ◽  
pp. 991-997 ◽  
Author(s):  
Matthias Drosten ◽  
Andreja Frilling ◽  
Thorsten Stiewe ◽  
Brigitte M. Pützer
Keyword(s):  
Thyroid Cancer ◽  
Cancer Treatment ◽  
Therapeutic Approach ◽  
Adenoviral Vector ◽  
Medullary Thyroid Cancer ◽  
Dominant Negative ◽  
Medullary Thyroid

scholarly journals AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment

2017 ◽  
Vol 5 (1) ◽  
pp. 151-159 ◽  
Author(s):  
Renata Jaskula-Sztul ◽  
Guojun Chen ◽  
Ajitha Dammalapati ◽  
April Harrison ◽  
Weiping Tang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Treatment ◽  
Targeted Delivery ◽  
Medullary Thyroid Cancer ◽  
Medullary Thyroid

Multifunctional unimolecular micelles conjugated with KE108, a superior MTC-targeting ligand, were developed for targeted delivery of AB3 to treat MTC.

Incidentally Found Medullary Thyroid Cancer: Treatment Rationale for Small Tumors

2004 ◽  
Vol 28 (4) ◽  
pp. 397-401 ◽  
Author(s):  
Andreas Raffel ◽  
Kenko Cupisti ◽  
Markus Krausch ◽  
Achim Wolf ◽  
Klaus-Martin Schulte ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Treatment ◽  
Medullary Thyroid Cancer ◽  
Medullary Thyroid

Abstract #1101 The Value of Calcitonin Calcium Stimulation Test Levels as Predictors of Medullary Thyroid Cancer.

2018 ◽  
Vol 24 ◽  
pp. 273-274
Author(s):  
Corin Badiu ◽  
Mara Baet ◽  
Ruxandra Dobrescu ◽  
Andra Caragheorgheopol ◽  
Corneci Cristina
Keyword(s):  
Thyroid Cancer ◽  
Medullary Thyroid Cancer ◽  
Stimulation Test ◽  
Medullary Thyroid ◽  
Calcium Stimulation

Immunoscintigraphy in Medullary Thyroid Cancer Using an 123I- or 111ln-Labelled Monoclonal Anti-CEA Antibody Fragment

1986 ◽  
Vol 25 (06) ◽  
pp. 227-231 ◽  
Author(s):  
Chr. Eilles ◽  
W. Spiegel ◽  
W. Becker ◽  
W. Börner ◽  
Chr. Reiners
Keyword(s):  
Bone Marrow ◽  
Thyroid Cancer ◽  
Potassium Iodide ◽  
Medullary Thyroid Cancer ◽  
Elevated Serum ◽  
Antibody Fragment ◽  
Special Importance ◽  
Medullary Thyroid ◽  
Medullary Cancer ◽  
Serum Cea

The monoclonal anti-CEA F(ab’)2 fragment MAb BW 431/31, labelled with 123I or111 In, was used for immunoscintigraphy (IS) in 9 patients with medullary cancer of the thyroid (CCC). The results of 11 studies lead to the following conclusions: 1) When using radioiodine as a label for MAb in IS, potassium iodide is absolutely necessary to block the thyroid which is of special importance in patients with thyroid cancer; 2) Preinjection of “cold” MAb reduces the relatively high unspecific uptake (especially in bone marrow) of MAb BW 431/31, which is of special importance for the antibody labelled with 111 In; 3) IS with MAb BW 413/31 in patients with CCC and elevated serum CEA is positive only in cases with large secondaries; and 4) In patients with CCC and several manifestations of secondaries, only a single (large) metastasis may be apparent.

NTRK3 receptor expression is strictly associated with medullary thyroid cancer RET mutation status

2014 ◽  
Author(s):  
Malgorzata Oczko-Wojciechowska ◽  
Michal Swierniak ◽  
Malgorzata Kowalska ◽  
Agnieszka Pawlaczek ◽  
Monika Kowal ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Medullary Thyroid Cancer ◽  
Receptor Expression ◽  
Mutation Status ◽  
Medullary Thyroid ◽  
Ret Mutation
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