Influence of nasogastric tubes on gastroesophageal reflux in preterm infants: A multiple intraluminal impedance study

2002 ◽  
Vol 141 (2) ◽  
pp. 277-279 ◽  
Author(s):  
Corinna S. Peter ◽  
Cornelia Wiechers ◽  
Bettina Bohnhorst ◽  
Jiri Silny ◽  
Christian F. Poets
Keyword(s):  
Gastroesophageal Reflux ◽  
Preterm Infants ◽  
Impedance Study ◽  
Nasogastric Tubes ◽  
Intraluminal Impedance

scholarly journals Gastroesophageal Reflux in Critically Ill Children: A Review

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Maria José Solana García ◽  
Jesús López-Herce Cid ◽  
César Sánchez Sánchez
Keyword(s):  
Gastroesophageal Reflux ◽  
Critically Ill ◽  
Critically Ill Children ◽  
Esophageal Mucosa ◽  
Duration Of Action ◽  
Nasogastric Tubes ◽  
Intraluminal Impedance ◽  
High Incidence ◽  
Antireflux Barrier ◽  
Ph Metry

Gastroesophageal reflux (GER) is very common in children due to immaturity of the antireflux barrier. In critically ill patients there is also a high incidence due to a partial or complete loss of pressure of the lower esophageal sphincter though other factors, such as the use of nasogastric tubes, treatment with adrenergic agonists, bronchodilators, or opiates and mechanical ventilation, can further increase the risk of GER. Vomiting and regurgitation are the most common manifestations in infants and are considered pathological when they have repercussions on the nutritional status. In critically ill children, damage to the esophageal mucosa predisposes to digestive tract hemorrhage and nosocomial pneumonia secondary to repeated microaspiration. GER is mainly alkaline in children, as is also the case in critically ill pediatric patients. pH-metry combined with multichannel intraluminal impedance is therefore the technique of choice for diagnosis. The proton pump inhibitors are the drugs of choice for the treatment of GER because they have a greater effect, longer duration of action, and a good safety profile.

Starch thickening of human milk is ineffective in reducing the gastroesophageal reflux in preterm infants: A crossover study using intraluminal impedance

2006 ◽  
Vol 148 (2) ◽  
pp. 265-268 ◽  
Author(s):  
Luigi Corvaglia ◽  
Marianna Ferlini ◽  
Raffaella Rotatori ◽  
Vittoria Paoletti ◽  
Rosina Alessandroni ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Human Milk ◽  
Crossover Study ◽  
Preterm Infants ◽  
Intraluminal Impedance

Nasogastric Feeding Tubes May Not Contribute to Gastroesophageal Reflux in Preterm Infants

2017 ◽  
Vol 35 (07) ◽  
pp. 643-647 ◽  
Author(s):  
Swati Murthy ◽  
Apryle Funderburk ◽  
Sheeja Abraham ◽  
Michele Epstein ◽  
Joan DiPalma ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Preterm Infants ◽  
Ph Monitoring ◽  
Feeding Tube ◽  
Acid Exposure ◽  
Total Fluid Intake ◽  
Nasogastric Feeding ◽  
Intraluminal Impedance ◽  
Significant Difference ◽  
Acid Exposure Time

Objective The objective was to determine if the presence of a nasogastric (NG) feeding tube is associated with increased gastroesophageal reflux (GER) and acid exposure in preterm infants. Study Design This is a retrospective study on preterm infants [gestational age (GA) <37 weeks] who were evaluated by multichannel intraluminal impedance and pH monitoring (MII-pH) between October 2009 and March 2016. Infants were divided into two groups, NG tube present and no feeding tube. GER events per hour and the percent of time with pH <4 during a 24-hour period were then compared. Results Eighty-three infants were included, 41 had an NG tube present and 42 did not. The group without an NG tube had significantly more reflux events per hour (2.3 ± 2.9 vs. 1.3 ± 0.8, p < 0.05) even after adjusting for differences in birth weight, GA, corrected GA, and total fluid intake. There was no significant difference in acidic events per hour and acid exposure time between the two groups. Conclusion The presence of a 5-French NG tube is not associated with an increase in GER or acid exposure in preterm infants. In fact, it appears that infants fed through an NG tube have fewer episodes of GER.

scholarly journals Prevalence and Risk Factors for Gastroesophageal Reflux in Symptomatic Very Preterm Neonates

2020 ◽  
Author(s):  
Yu Hu ◽  
Jian-Hua Fu ◽  
Shu-Cheng Zhang
Keyword(s):  
Risk Factors ◽  
Gastroesophageal Reflux ◽  
Confidence Interval ◽  
Preterm Infants ◽  
Odds Ratio ◽  
Preterm Neonates ◽  
Very Preterm ◽  
Intraluminal Impedance ◽  
Immature Development ◽  
Impedance Monitoring

Abstract Background Because of immature development, preterm infants are prone to respiratory and digestive symptoms of dyspnea, vomiting, and aspiration pneumonia. These symptoms are often observed in infants with gastroesophageal reflux (GER). However, the relationship between GER and these symptoms remain unclear.Methods A cohort of 61 preterm infants born at 32 weeks of gestation or earlier with respiratory or digestive symptoms were retrospectively reviewed. All the preterm infants underwent 24-hour pH-multichannel intraluminal impedance monitoring. Clinical data were analyzed using logistic regression analyses.Results Among the 61 symptomatic preterm infants, 34 were positive for pathologic GER with a prevalence of 55.7%. The GER associated symptoms included apnea (42.6%), cyanosis (19.7%), vomiting (14.8%), pneumonia (9.8%), and poor weight gain (13.1%). These respiratory and digestive symptoms were more frequent in infants with pathologic GER than in those without. (p<0.05) The risk factors for GER included severe BPD (odds ratio [OR], 6.890; 95% confidence interval [CI], 1.125-42.209). Probiotics and delayed full oral feeds reduced the risk of GER (odds ratio [OR], 0.642; 95% confidence interval [CI], 0.457-0.901, p<0.05; OR, 0.234, 95% CI, 0.069-0.794, p<0.05). Conclusions The prevalence of GER is high in the symptomatic preterm infants. GER aggravates the respiratory and digestive symptoms holding that not all the symptoms are GER associated. Probiotics and delayed full oral feeds can decrease the prevalence of GER.

scholarly journals Prevalence and Risk Factors for Gastroesophageal Reflux in Symptomatic Very Preterm Neonates

2020 ◽  
Author(s):  
Yu Hu ◽  
Hua Fu ◽  
Cheng Zhang
Keyword(s):  
Risk Factors ◽  
Gastroesophageal Reflux ◽  
Preterm Infants ◽  
Preterm Neonates ◽  
Very Preterm ◽  
Intraluminal Impedance ◽  
Immature Development ◽  
Impedance Monitoring ◽  
The Relationship ◽  
Poor Weight Gain

Abstract Objectives Because of immature development, preterm infants are prone to respiratory and digestive symptoms, such as dyspnea, vomiting, and aspiration pneumonia. These symptoms are often observed in infants with gastroesophageal reflux (GER). However, the relationship between GER and these symptoms remains unclear.Methods A cohort of 61 preterm infants born at 32 weeks of gestation or earlier with respiratory or digestive symptoms were retrospectively reviewed. All the preterm infants underwent 24-hour pH-multichannel intraluminal impedance monitoring. Clinical data were analyzed using logistic regression analyses.Results Among the 61 symptomatic preterm infants, 34 were positive for pathologic GER with a prevalence of 55.7%. The GER-associated symptoms included apnea (42.6%), cyanosis (19.7%), vomiting (14.8%), pneumonia (9.8%), and poor weight gain (13.1%). These respiratory and digestive symptoms were more frequent in infants with pathologic GER than in those without (p<0.05). The risk factors for GER included severe bronchopulmonary dysplasia (odds ratio [OR], 6.890; 95% confidence interval [CI], 1.125-42.209). Probiotics and delayed full oral feeds reduced the risk of GER (OR, 0.642; 95% CI, 0.457-0.901, p<0.05; OR, 0.234, 95% CI, 0.069-0.794, p<0.05). Conclusions The prevalence of GER is high in symptomatic preterm infants. GER aggravates the respiratory and digestive symptoms; however, such symptoms are not always GER-associated. Probiotics and delayed full oral feeds can decrease the prevalence of GER.

Mechanisms of liquid and gas gastroesophageal reflux in healthy preterm infants. A combined manometric and impedance study

2003 ◽  
Vol 124 (4) ◽  
pp. A41
Author(s):  
Taher Omari ◽  
Nathalie Rommel ◽  
Esther Staunton ◽  
Louise Goodchild ◽  
Ross Lontis ◽  
...  
Keyword(s):  
Gastroesophageal Reflux ◽  
Preterm Infants ◽  
Impedance Study
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