Human papillomavirus, type 40-associated papilloma, and concurrent Kaposi's sarcoma involving the anterior hard palate of an HIV-positive man

2003 ◽  
Vol 95 (1) ◽  
pp. 80-84 ◽  
Author(s):  
K.Mark Anderson ◽  
Carl M. Allen ◽  
Gerard J. Nuovo
Keyword(s):  
Human Papillomavirus ◽  
Kaposi's Sarcoma ◽  
Hard Palate ◽  
Kaposi’S Sarcoma ◽  
Hiv Positive

Classic Kaposi's sarcoma on the glans penis only: Case report

1997 ◽  
Vol 64 (1) ◽  
pp. 134-135
Author(s):  
E. Gastaldi ◽  
S. Benvenuti ◽  
B. Mennini ◽  
M. Iacoviello ◽  
M. Caviglione ◽  
...  
Keyword(s):  
Case Report ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Positive Patient ◽  
Glans Penis ◽  
Hiv Positive ◽  
Partial Penectomy

The Authors report a case of Kaposi's sarcoma presenting on the glans penis only in a non-HIV positive patient, who had not been treated with immuno-suppressive drugs. In our experience and according to a review of specific literature, choice treatment would seem to be a radiotherapeutic approach followed by partial penectomy in the event of recurrence.

scholarly journals Simultaneous Association of Pulmonary Tuberculosis and Kaposi’s Sarcoma in an Immunocompetent Subject: A Case Report and Literature Review

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Sofia Baina ◽  
Jihane Achrane ◽  
Jouda Benamor ◽  
Jamal Eddine Bourkadi
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Pulmonary Tuberculosis ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Hiv Positive ◽  
Negative Patient ◽  
Different Types ◽  
Hiv Negative

Kaposi’s Sarcoma (KS) occurs as a pathological entity that may be classified into four different types: classic, endemic, epidemic, and iatrogenic. It can arise among HIV-positive subjects or within immunosuppression, yet exceptionally of tuberculous origin. We describe a new case report of an HIV-negative patient, manifesting Kaposi’s disease in the course of tuberculosis, with the aim to assess this uncommon disorder and to outline this rare atypical association.

scholarly journals Kaposi's sarcoma of the hard palate

2016 ◽  
Vol 115 (10) ◽  
pp. 883-884 ◽  
Author(s):  
Yu-Hsueh Wu ◽  
Hsiang Yang ◽  
Andy Sun ◽  
Hsin-Ming Chen
Keyword(s):  
Kaposi's Sarcoma ◽  
Hard Palate ◽  
Kaposi’S Sarcoma

scholarly journals The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Peter D. Burbelo ◽  
Joseph A. Kovacs ◽  
Jason Wagner ◽  
Ahmad Bayat ◽  
Craig S. Rhodes ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Hiv Positive ◽  
Infectious Agents ◽  
Hiv Patients ◽  
Non Hodgkin Lymphoma ◽  
Oral Hairy Leukoplakia ◽  
Hairy Leukoplakia ◽  
Antibody Levels

Although HIV-positive patients are at higher risk for developing a variety of infection-related cancers, the prevalence of infections with the seven known cancer-associated viruses has not been studied. Luciferase immunoprecipitation systems were used to evaluate antiviral antibodies in four 23-person groups: healthy blood donors and HIV-infected patients with oral hairy leukoplakia (OLP), Kaposi's sarcoma (KS), or non-Hodgkin lymphoma (NHL). Antibody profiling revealed that all HIV-positive individuals were strongly seropositive for anti-gp41 and antireverse transcriptase antibodies. However, anti-p24 HIV antibody levels were highly variable and some OLP and KS patients demonstrated weak or negative responses. Profiling two EBV antigens revealed no statistical difference in antibody levels among the three HIV-infected groups. A high frequency of KSHV infection was detected in HIV patients including 100% of KS, 78% of OLP, and 57% of NHL patients. Most HIV-infected subjects (84%) showed anti-HBV core antibodies, but only a few showed antibodies against HCV. MCV seropositivity was also common (94%) in the HIV-infected individuals and KS patients showed statistically higher antibody levels compared to the OLP and NHL patients. Overall, 68% of the HIV-infected patients showed seropositivity with at least four cancer-associated viruses. Antibody profiles against these and other infectious agents could be useful for enhancing the clinical management of HIV patients.

scholarly journals Chylothorax associated with non-endemic Kaposi’s sarcoma

2013 ◽  
Vol 14 (3) ◽  
pp. 141-143
Author(s):  
Kamal Verma ◽  
Miriam Haverkamp ◽  
Mukendi Kayembe ◽  
Zola Musimar
Keyword(s):  
Computed Tomography ◽  
Pleural Effusion ◽  
Pleural Fluid ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Hiv Positive ◽  
Clinical Scenario ◽  
Diagnostic Challenge ◽  
Lethal Outcome ◽  
Traumatic Chylothorax

Chylothorax is a rare cause of pleural effusion, seen in approximately 2% of cases. In HIV-positive patients with Kaposi’s sarcoma (KS), the development of chylothorax presents as a diagnostic challenge with an aggressive course and poor, often lethal outcome. In this clinical scenario, the aetiology of chylothorax may include infections and malignancy, while pleural fluid examination and computed tomography of the mediastinum may fail to establish a cause. We present a case of KS-associated non-traumatic chylothorax resulting in death, and a review of available literature on this condition.

scholarly journals Classic Kaposi's Sarcoma (non-hiv-associated) of oral cavity: a case report

2017 ◽  
Vol 16 ◽  
pp. 1-6
Author(s):  
Marcelo Carlos Bortoluzzi ◽  
Ramon Cesar Godoy Gonçalves ◽  
Cristina Maria de Freitas Zanellato ◽  
Juliana Cama Ramacciato ◽  
Roberto de Oliveira Jabur
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Female Patient ◽  
Rare Case ◽  
Kaposi's Sarcoma ◽  
Hard Palate ◽  
Malignant Neoplasm ◽  
Kaposi’S Sarcoma ◽  
Immunohistochemical Profile

Kaposi’s sarcoma (KS) is a locally aggressive multicentric mucocutaneous malignant neoplasm. The aim of this article is to report and discuss the immunohistochemical profile of a rare case of classic primary Oral Kaposi’s sarcoma presenting on the hard palate of a female patient which was non-HIV and was not immunocompromised.

scholarly journals A case of Kaposi's sarcoma of the hard palate with AIDS.

1993 ◽  
Vol 39 (12) ◽  
pp. 1353-1355 ◽  
Author(s):  
Hideki Kizu ◽  
Yoshiaki KOMIYA ◽  
Ikuhiro UCHIDA ◽  
Yoshiharu MAEDA
Keyword(s):  
Kaposi's Sarcoma ◽  
Hard Palate ◽  
Kaposi’S Sarcoma

scholarly journals Management of an oncological wound: Diagnosis, conflicting therapies and decision-making

2020 ◽  
Vol 21 (Issue 1 Volume 21, 2020) ◽  
pp. 13-16
Author(s):  
Tommaso Bianchi ◽  
Ambra Di Altobrando ◽  
Yuri Merli ◽  
Federico Tartari ◽  
Barbara Manfredi ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Hiv Positive ◽  
Low Grade ◽  
Vascular Tumour ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Human Herpes Virus ◽  
Blistering Disease

This article presents the case of a non-HIV-positive patient who contemporaneously suffered from Kaposi’s sarcoma and bullous pemphigoid. Kaposi’s sarcoma is a rare low-grade vascular tumour associated with human herpes virus 8 infection, while bullous pemphigoid is the most common autoimmune subepidermal blistering disease in western countries.

scholarly journals Unique Circulating microRNA Profiles in Epidemic Kaposi’s Sarcoma

2020 ◽  
Author(s):  
Haruna Muwonge ◽  
Hassan Kasujja ◽  
Carolyne Atugonza ◽  
Josephine Kasolo ◽  
Allan Lugaajju ◽  
...  
Keyword(s):  
Kaposi's Sarcoma ◽  
Early Stage ◽  
Human Herpesvirus ◽  
Kaposi’S Sarcoma ◽  
Hiv Positive ◽  
Circulating Microrna ◽  
Early Stage Disease ◽  
Circulating Mirna ◽  
Serum Mirnas ◽  
Potential Biomarkers

Abstract BackgroundThe Human herpesvirus 8 (HHV-8), causes Kaposi's sarcoma (KS). Kaposi sarcoma in HIV/AIDS patients is referred to as epidemic KS, and is the most common HIV-related malignancy worldwide. Lack of a diagnostic assay to detect latent and early stage disease has increased disease morbidity and mortality. Serum miRNAs have previously been used as potential biomarkers of normal physiology and disease. In the current study, we profiled the unique serum miRNAs in patients with epidemic KS to generate baseline data to aid in developing a miRNA-based non-invasive biomarker assay for Epidemic KS. MethodsThis was a comparative cross-sectional study involving 27 patients with epidemic KS, and 27 HIV-positive adults with no prior diagnosis, or clinical manifestation of KS. DNA and RNA were isolated from blood and serum collected from study participants respectively. Nested PCR for circulating HHV-8 DNA was performed on the isolated DNA, whereas miRNA library preparation and sequencing for circulating miRNA was performed on the RNA samples. The miRge2 pipeline and EdgeR were used to analyze the sequencing data. Results Fifteen out of the 27 epidemic KS positive subjects (55.6%) tested positive for HHV-8 DNA, whereas only 3 (11.1%) out of the 27 HIV positive, KS negative subjects tested positive for HHV-8 DNA. Additionally, we found a unique miRNA expression signature in 49 circulating miRNAs in epidemic KS subjects compared to subjects with no epidemic KS, with 41 miRNAs upregulated and 8 miRNAs down regulated. Subjects with latent KS infection had a differential upregulation of circulating miR-193a compared to HIV-positive, KS negative subjects for whom circulating HHV-8 DNA was not detected. Further analysis of serum from epidemic KS patients revealed a miRNA signature according to KS tumor status and time since first HIV diagnosis. ConclusionsThis study reveals unique circulating miRNA profiles in the serum of patients with epidemic KS versus HIV-infected subjects with no KS, as well as in subjects with latent KS. Many of the dysregulated miRNAs in epidemic KS patients were previously reported to have crucial roles in KS infection and latency, highlighting their promising roles as potential biomarkers of latent or active KS infection.

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