Complete molecular remission during biologic response modifier therapy for Sézary syndrome is associated with enhanced helper T type 1 cytokine production and natural killer cell activity

2001 ◽  
Vol 45 (2) ◽  
pp. 208-216 ◽  
Author(s):  
Elisa K. Yoo ◽  
Maureen Cassin ◽  
Stuart R. Lessin ◽  
Alain H. Rook
1987 ◽  
Vol 166 (1) ◽  
pp. 271-276 ◽  
Author(s):  
D B Magilavy ◽  
A D Steinberg ◽  
S L Latta

This study demonstrates a profound elevation of NK activity, as measured by cytotoxicity to YAC-1 targets in a 4-h incubation 51Cr-release assay, of freshly isolated hepatic NPC from both MRL/lpr and (NZB X NZW)F1 mice. This marked increase was not observed in splenic or peripheral blood NK. The hepatic NK were nonadherent, radioresistant, Ly-1-,2-, and AGM1+. Furthermore, biologic response modifiers can further augment hepatic NK activity in these autoimmune strains.


1996 ◽  
Vol 67 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Marcus Wenner ◽  
Noriyuki Kawamura ◽  
Hitoshi Miyazawa ◽  
Yukihiro Ago ◽  
Toshio Ishikawa ◽  
...  

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