Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: A meta-analysis

2001 ◽  
Vol 37 (5) ◽  
pp. 461-470 ◽  
Author(s):  
John P.A. Ioannidis ◽  
Deeb Salem ◽  
Priscilla W. Chew ◽  
Joseph Lau
Keyword(s):  
Clinical Effect ◽  
Meta Analysis ◽  
Cardiac Ischemia ◽  
Acute Cardiac Ischemia

Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: A meta-analysis

2001 ◽  
Vol 37 (5) ◽  
pp. 478-494 ◽  
Author(s):  
Ethan M. Balk ◽  
John P.A. Ioannidis ◽  
Deeb Salem ◽  
Priscilla W. Chew ◽  
Joseph Lau
Keyword(s):  
Emergency Department ◽  
Meta Analysis ◽  
Cardiac Ischemia ◽  
Acute Cardiac Ischemia

Diagnosing acute cardiac ischemia in the emergency department: A systematic review of the accuracy and clinical effect of current technologies

2001 ◽  
Vol 37 (5) ◽  
pp. 453-460 ◽  
Author(s):  
Joseph Lau ◽  
John P.A. Ioannidis ◽  
Ethan M. Balk ◽  
Catherine Milch ◽  
Norma Terrin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Emergency Department ◽  
Clinical Effect ◽  
Cardiac Ischemia ◽  
Acute Cardiac Ischemia

scholarly journals Management of anticoagulants in delayed bleeding after endoscopic resection: A systematic review and meta-analysis

2021 ◽  
Vol 09 (07) ◽  
pp. E1128-E1135
Author(s):  
Xianhong Zhao ◽  
Yangxue Huang ◽  
Jiarong Li ◽  
Aoqiang Zhou ◽  
Gengxin Chen ◽  
...  
Keyword(s):  
Endoscopic Resection ◽  
Clinical Effect ◽  
Meta Analysis ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Delayed Bleeding ◽  
Best Management ◽  
Significant Difference ◽  
Meta Analyses ◽  
Bridge Therapy

Abstract Background and study aims Delayed bleeding and thrombotic events are uncontrolled adverse events that are hard to balance in patients receiving anticoagulants after endoscopic resection. The present study aims to assess the clinical effect of warfarin, when compared to direct oral anticoagulants (DOACs), in terms of delayed bleeding and thrombotic events. Methods A comprehensive electronic literature search was conducted for eligible literature. Pairwise meta-analyses were performed on outcomes of delayed bleeding and thrombotic events. Two networks within the Bayesian framework were established based on the management of anticoagulants and type of DOAC. Results Eight cohort studies with 2,046 patients were eligible for inclusion, including 1,176 patients treated with warfarin and 870 with DOACs. There was no significant difference between warfarin and DOACs, in terms of delayed bleeding (OR = 1.29, 95 % CI [0.99–1.69]) and thromboembolism (OR = 2.0, 95 % CI [0.32–12.39]). In the network meta-analyses for delayed bleeding, the rank probabilities revealed that the safest management was discontinuous warfarin without heparin bridge therapy (HBT). Rank probabilities for the types of DOACs demonstrated that the safest drug was dabigatran. Conclusions There was no significant difference in delayed bleeding and thromboembolism between warfarin and DOACs in patients receiving endoscopic treatment. In terms of delayed bleeding, discontinuous warfarin without HBT was suggested as the best management, and dabigatran was recommended as the best type of DOAC.

scholarly journals A Meta-analysis of Major Complications between Traditional Pacemakers and Leadless Pacemakers

2020 ◽  
Author(s):  
Yun-Qing Chen
Keyword(s):  
Pericardial Effusion ◽  
Risk Ratio ◽  
Clinical Effect ◽  
Meta Analysis ◽  
Cochrane Central Register ◽  
Inclusion Criteria ◽  
Cardiac Perforation ◽  
Major Complications ◽  
Central Register ◽  
Reported Data

Objectives: We aim to compare the major complications between leadless pacemakers and traditional pacemakers.Background: Leadless pacemakers, which are increasingly used in clinical practice, have several advantages compared with traditional pacemakers in avoiding pocket- and lead-related complications. However, the clinical effect of leadless pacemakers remains controversial.Methods: PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), the CNKI database, and the Wanfang database were searched from July 2013 to December 2019. Studies comparing leadless pacemakers and traditional pacemakers were included. The primary end point was major complications. The secondary end points were cardiac perforation/pericardial effusion, device revision or extraction, loss of device function, and death.Results: Six studies fulfilled the inclusion criteria. Only four of the six studies reported data on major complications.Leadless pacemakers were associated with a lower incidence of major complications (risk ratio 0.33, 95% confidenceinterval 0.25–0.44, P < 0.00001, I² = 49%). We extracted data on cardiac perforation/pericardial effusion, device revisionor extraction, loss of device function, and death from six studies. Our meta-analysis showed that leadless pacemakershave a higher risk of cardiac perforation or pericardial effusion (risk ratio 4.28, 95% confidence interval 1.66–11.08,P = 0.003, I² = 0%). No statistically significant differences were found for mortality, device revision or extraction, andloss of device function.Conclusion: Compared with traditional pacemakers, leadless pacemakers have a significantly decreased risk of majorcomplications, but have a higher risk of cardiac perforation or pericardial effusion.

Resolution of an Acute Cardiac Ischemia After the Removal of a Surgical Drain in Mitral and Tricuspid Valve Repair

2011 ◽  
Vol 91 (6) ◽  
pp. e94 ◽  
Author(s):  
Giuseppe Iaci ◽  
Alessandro Castiglioni ◽  
Andrea Fumero ◽  
Mauro Carlino ◽  
Alberto Margonato ◽  
...  
Keyword(s):  
Tricuspid Valve ◽  
Cardiac Ischemia ◽  
Tricuspid Valve Repair ◽  
Valve Repair ◽  
Acute Cardiac Ischemia ◽  
Surgical Drain

scholarly journals A Systematic Review and Meta-Analysis on a Disease in TCM: Astragalus Injection for Gathering Qi Depression

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Yanxiang Ha ◽  
Po Huang ◽  
Yumeng Yan ◽  
Xiaolong Xu ◽  
Bo Li ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systematic Review ◽  
Natural Science ◽  
Clinical Effect ◽  
Distress Syndrome ◽  
Meta Analysis ◽  
Chinese Traditional Medicine ◽  
Walking Test ◽  
Long Time ◽  
Important Drug

Zong Qi depression is a disease recorded in the literature of Chinese traditional medicine for a long time. In recent years, the theory of Zong Qi depression has been more and more applied to the diagnosis and treatment of a variety of diseases. Astragalus is the most important drug used to treat the depression of Zong Qi. Meanwhile, Astragalus injection is also widely used in a variety of diseases in accordance with the manifestations of Zong Qi subsidence. However, there is a lack of systematic review or meta-analysis of the clinical effect of Astragalus injection in the treatment of Zong Qi subsidence. Therefore, we searched for diseases characterized by symptoms of Zong Qi subsidence (including heart failure, respiratory failure, acute respiratory distress syndrome, and acute lung injury) and evaluated the effect of Astragalus injection in these diseases with mortality and distance of a 6-minute walking test. The results showed that the mortality of patients with subsidence of Zong Qi decreased in 1 month (OR, 0.26 [0.12, 0.61], 95% CI, P=0.002) and 1 year (OR, 0.38 [0.20, 0.69], 95% CI, P=0.002) after using Astragalus injection. The distance of 6-minute walking test after 7 (MD, 91.60 [6.89, 176.31], 95% CI, P=0.03), 14 (MD, 22.62 [13.80, 31.43], 95% CI, P<0.00001), and 28 days (MD, 108.31 [30.02, 186.59], 95% CI, P=0.007) of using Astragalus injection also increased. Therefore, we believe that Astragalus injection has a certain therapeutic effect on the depression of Zong Qi.

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