Influence of willow bark extract on cyclooxygenase activity and on tumor necrosis factor [alpha ] or interleukin 1[beta ] release in vitro and ex vivo

2003 ◽  
Vol 73 (3) ◽  
pp. 272-274 ◽  
Author(s):  
Irmela Wagner ◽  
Cornelia Greim ◽  
Stefan Laufer ◽  
Lutz Heide ◽  
Christoph H. Gleiter
Keyword(s):  
Ex Vivo ◽  
Interleukin 1 ◽  
Bark Extract ◽  
Interleukin 1 Beta ◽  
Necrosis Factor Alpha ◽  
Cyclooxygenase Activity ◽  
Willow Bark ◽  
Factor Alpha ◽  
Necrosis Factor

Effects of tumour necrosis factor-alpha and interleukin-1 beta on in vitro development of bovine secondary follicles

2018 ◽  
Vol 53 (4) ◽  
pp. 997-1005 ◽  
Author(s):  
Lais R. F. M. Paulino ◽  
Ellen V. Cunha ◽  
Anderson W. Barbalho Silva ◽  
Glaucinete B. Souza ◽  
Ewerton P. F. Lopes ◽  
...  
Keyword(s):  
Tumour Necrosis ◽  
Interleukin 1 ◽  
Tumour Necrosis Factor Alpha ◽  
Interleukin 1 Beta ◽  
Necrosis Factor Alpha ◽  
In Vitro Development ◽  
Factor Alpha ◽  
Vitro Development ◽  
Necrosis Factor

Differential effects of cytokines on thermosensitive neurons in guinea pig preoptic area slices

1991 ◽  
Vol 261 (5) ◽  
pp. R1096-R1103 ◽  
Author(s):  
M. Shibata ◽  
C. M. Blatteis
Keyword(s):  
Guinea Pig ◽  
Preoptic Area ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Necrosis Factor Alpha ◽  
Firing Rates ◽  
Artificial Cerebrospinal Fluid ◽  
Cold Sensitive ◽  
Factor Alpha ◽  
Necrosis Factor

This study was undertaken to determine whether the reported different courses of the febrile responses to the cytokines interleukin-1 beta (IL-1), interferon-alpha 2 (IFN), and tumor necrosis factor-alpha (TNF) might have neuroelectrophysiological correlates. The reactions of individual thermosensitive neurons in the preoptic area (POA) were evaluated by recording their extracellular single-unit firing rates (FR) in slices of guinea pig POA perfused with artificial cerebrospinal fluid (aCSF), human recombinant IL-1 (50-500 ng), IFN (1,000-8,000 U), and TNF (400-5,000 ng) (all doses per min/ml aCSF); thermosensitivity was assessed by FR responses to changes of perfusate temperature (32-42 degrees C). Overall, these cytokines depressed the FR of warm-sensitive units and excited those of cold-sensitive units, in agreement with expectations. However, the responses of individual neurons treated with two or all three cytokines were dissimilar: 61% of the units tested reacted differentially to two or three cytokines, 32% exhibited identical responses, and 7% had no response to any cytokine. These results support the possibility that IL-1, IFN, and TNF may affect not the same but rather distinct neurons functionally connected to common pyrogenic effectors. Thus they suggest that differential neuronal substrates may be utilized by each cytokine to exert its pyrogenic effect.

scholarly journals Keratinocyte growth factor, tumor necrosis factor-alpha and interleukin-1 beta gene expression in cultured fibroblasts and keratinocytes from burned patients

2013 ◽  
Vol 28 (8) ◽  
pp. 551-558 ◽  
Author(s):  
Alfredo Gragnani ◽  
Bruno Rafael Müller ◽  
Ismael Dale Contrim Guerreiro da Silva ◽  
Samuel Marcos Ribeiro de Noronha ◽  
Lydia Masako Ferreira
Keyword(s):  
Gene Expression ◽  
Tumor Necrosis ◽  
Keratinocyte Growth Factor ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Necrosis Factor Alpha ◽  
Cultured Fibroblasts ◽  
Factor Alpha ◽  
Beta Gene ◽  
Necrosis Factor
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