Comparison of inflammatory responses to genetically engineered hypoallergenic derivatives of the major birch pollen allergen Bet v 1 and to recombinant Bet v 1 wild type in skin chamber fluids collected from birch pollen–allergic patients

2000 ◽  
Vol 106 (1) ◽  
pp. 101-109 ◽  
Author(s):  
Anna Nopp ◽  
Gunilla Halldén ◽  
Joachim Lundahl ◽  
Eva Johansson ◽  
Susanne Vrtala ◽  
...  
Keyword(s):  
Inflammatory Responses ◽  
Birch Pollen ◽  
Genetically Engineered ◽  
Pollen Allergen ◽  
Wild Type ◽  
Bet V 1 ◽  
Birch Pollen Allergen ◽  
Derivatives Of

Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly

2010 ◽  
Vol 126 (5) ◽  
pp. 1024-1031.e8 ◽  
Author(s):  
Raffaela Campana ◽  
Susanne Vrtala ◽  
Bernhard Maderegger ◽  
Peter Jertschin ◽  
Gottfried Stegfellner ◽  
...  
Keyword(s):  
Birch Pollen ◽  
Pollen Allergen ◽  
Bet V 1 ◽  
Birch Pollen Allergen ◽  
Derivatives Of ◽  
Rational Sequence

scholarly journals Caveolar transport through nasal epithelium of birch pollen allergen Bet v 1 in allergic patients

2009 ◽  
Vol 124 (1) ◽  
pp. 135-142.e21 ◽  
Author(s):  
Sakari Joenväärä ◽  
Pirkko Mattila ◽  
Jutta Renkonen ◽  
Antti Mäkitie ◽  
Sanna Toppila-Salmi ◽  
...  
Keyword(s):  
Birch Pollen ◽  
Pollen Allergen ◽  
Nasal Epithelium ◽  
Bet V 1 ◽  
Birch Pollen Allergen

scholarly journals Genetic Variants in CHIA and CHI3L1 Are Associated with the IgE Response to the Ascaris Resistance Marker ABA-1 and the Birch Pollen Allergen Bet v 1

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0167453 ◽  
Author(s):  
Nathalie Acevedo ◽  
Adriana Bornacelly ◽  
Dilia Mercado ◽  
Per Unneberg ◽  
Irene Mittermann ◽  
...  
Keyword(s):  
Genetic Variants ◽  
Birch Pollen ◽  
Pollen Allergen ◽  
Resistance Marker ◽  
Bet V 1 ◽  
Birch Pollen Allergen ◽  
Ige Response

Two members of the Bet v 1 gene family encoding birch pathogenesis-related proteins display different patterns of root expression and wound-inducibility

1998 ◽  
Vol 25 (4) ◽  
pp. 459 ◽  
Author(s):  
Pascal Poupard ◽  
Désiré-Georges Strullu ◽  
Philippe Simoneau
Keyword(s):  
Birch Pollen ◽  
Polyclonal Antiserum ◽  
Pollen Allergen ◽  
Pathogenesis Related Proteins ◽  
Bet V 1 ◽  
New Family ◽  
Pathogenesis Related ◽  
Birch Pollen Allergen ◽  
Root Organogenesis ◽  
Related Proteins

Bet v 1-SC genes constitute a subset of a multigene family in birch (Betula pendula Roth) that includes the gene for the major pollen allergen and encode proteins belonging to a new family of intracellular pathogenesis-related proteins. We have investigated the expression in birch roots of the Bet v 1-SC1 and Bet v 1-SC3 genes by northern and reverse-transcription-polymerase chain reaction analyses. Only Bet v 1-SC3 was found to be highly expressed in roots under basal conditions but this gene was not wound-inducible. Conversely the expression of the Bet v 1-SC1 gene was markedly transiently induced 8 to 9 h after the stress. Immunoblotting with polyclonal antiserum raised against the major birch pollen allergen confirmed that Bet v 1-related polypeptides are present in root extracts. This first report of Bet v 1-SC gene expression and wound-inducibility in birch roots suggests a possible function of proteins encoded by these genes in plant defense and/or root organogenesis.

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