Antibacterial and antibiofilm activity of bacterially reduced graphene oxide against some MDR bacterial pathogens isolated from urinary tract infections

2022 ◽  
Author(s):  
Muktad Fadel Almamad ◽  
Nawfal Hussein Aldujaili
Keyword(s):  
Graphene Oxide ◽  
Urinary Tract ◽  
Reduced Graphene Oxide ◽  
Urinary Tract Infections ◽  
Bacterial Pathogens ◽  
Antibiofilm Activity ◽  
Reduced Graphene ◽  
Tract Infections

scholarly journals Selective isolation and eradication of E. coli associated with urinary tract infections using anti-fimbrial modified magnetic reduced graphene oxide nanoheaters

2017 ◽  
Vol 5 (40) ◽  
pp. 8133-8142 ◽  
Author(s):  
Fatima Halouane ◽  
Roxana Jijie ◽  
Dalila Meziane ◽  
Chengnan Li ◽  
Santosh K. Singh ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Pathogenic Bacteria ◽  
Selective Isolation ◽  
E Coli ◽  
Reduced Graphene ◽  
Tract Infections ◽  
Efficient Elimination ◽  
Magnetic Reduced Graphene Oxide

The fast and efficient elimination of pathogenic bacteria from water, food or biological samples such as blood remains a challenging task.

scholarly journals The Prevalence of Bacterial Pathogens associated with Urinary Tract Infection (UTI) among Patients attending Kam Medical Consult Clinic, Uganda.

2021 ◽  
Author(s):  
◽  
Gerald Turyatunga
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Bacterial Pathogens ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Etiological Agents ◽  
Tract Infections

Background: A urinary tract infection (UTIs) is a common type of infection caused by bacteria that travel up the urethra to the bladder. Globally, it is reported that 150 million people are diagnosed with a UTI annually, costing the world economy over 6 million US dollars in treatment and work loss. Studies conducted in the in-patients pediatric ward of Muhimbili Hospital in Tanzania and Mulago National Referral Hospital in Uganda between five to ten years reported the prevalence of UTI to be 16.8% and 14.6% respectively. On average at Kam Medical Consult Clinic, patients who turn up in the laboratory are about 20%, and 50% of patients present with recurring UTIs clinically. Therefore,  there is a need to establish and investigate the prevalence of bacterial pathogens associated with UTI and multiple pathogens that are not known. Methodology: The cross-sectional study was carried out at Kam medical consult clinic (KMCC) located in Kafeero zone Mulago II Kawempe division. The study population was adults and children presenting with symptoms of urinary tract infection. 120 Midstream urine Samples were collected from patients presenting clinical signs of UTI. The diagnosis was done through macroscopy dry chemistry, microscopy, and culture. Results Among the sampled population, 33% of males had urinary tract infections while 67% of females had urinary tract infections.  88.5% were outpatients while 11.5 % were in-patients The overall prevalence of UTI among patients was 63.3% with children aged (1-10) having a prevalence of 5.8 %. Conclusion and recommendation: E.coli is an etiological agent causing UTIs in male and female patients presenting UTI at Kam Medical Consult Clinic. Other etiological agents included Klebsiella, Coliform, Enterococcus species, staphylococcus aureus, pseudomonas species, and candida species. There is a need to monitor the profile of etiological bacteria of UTI through culture and sensitivity regularly. 

Antimicrobial resistance of bacterial pathogens isolated from canine urinary tract infections

2020 ◽  
Vol 241 ◽  
pp. 108540
Author(s):  
Zhuoling Yu ◽  
Yao Wang ◽  
Yanyun Chen ◽  
Min Huang ◽  
Yang Wang ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Urinary Tract Infections ◽  
Bacterial Pathogens ◽  
Tract Infections

scholarly journals Microfluidic system for the identification of bacterial pathogens causing urinary tract infections

2015 ◽  
Author(s):  
Holger Becker ◽  
Nadine Hlawatsch ◽  
Tommy Haraldsson ◽  
Wouter van der Wijngaart ◽  
Anders Lind ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Bacterial Pathogens ◽  
Microfluidic System ◽  
Tract Infections

scholarly journals Bacterial Pathogens of Patients with Urinary Tract Infections and Antibiotics Susceptibility in Taiz Governorate-Yemen

2019 ◽  
Vol 30 (1) ◽  
pp. 43 ◽  
Author(s):  
Ahmed Sallem Alganady
Keyword(s):  
Staphylococcus Aureus ◽  
Urinary Tract ◽  
Incidence Rate ◽  
Urinary Tract Infections ◽  
Bacterial Pathogens ◽  
Urine Samples ◽  
High Rate ◽  
Penicillin G ◽  
Antibiotics Susceptibility ◽  
Tract Infections

One of the most prevalent bacterial infections are urinary tract infections (UTIs), which affect any age of individuals and they appear higher in women than men, the major problem regarding UTIs are the difficult of antibiotics treatment, due to bacterial pathogens resistance. So, the current study aimed to detect the types of bacterial pathogens and their antibiotics susceptibility of UTIs in Taiz Governorate – Yemen. In this cohort study, one hundred and ten (110) mid-stream urine samples were collected from a symptomatic UTIs patient, the type of bacterial pathogens was identified by using standard bacteriological media and biochemical tests and determine the antibiotics sensitivity to these bacteria using disk diffusion tests. Out of one hundred and ten of urine samples:: 65 of patients were females and 45 were males and the bacterial growth in these patients were sixty-four [46(58.2%)] : (33.7%) were females and (24.5%) were males. Our findings showed that the types of bacterial pathogens include: Escherichia coli (32.7%), Klebsiellapneumoniae (9.1%), Staphylococcus aureus (6.4%), Proteus mirabilis (5.5%) and Pseudomonas aeruginosa (4.5%). The majority (57.9%) of the isolates were from female. The prevalence of UTIs is high among patients with age between 16-30 years with the incident rate 20.9 %, age groups 1-15 years have the lower incidence rate 5.5%. UTIs were more prevalent among the rural area population, there were 50% than the population of the city center, there were 8.2% and the rate of infections were more prevalent among illiterate (no read and write) patients with incidence rate 44.5% , compared to literate (read and write) patients 13.6%. Also, our results showed that the sensitivity test against bacterial pathogens as All bacterial isolates was more sensitive to Ciprofloxacin, followed by Amikacin, Gentamycin , Cefotaxime (except Staphylococcus aureus Cefotaxime (42.9%) and Ceftriaxone (except Staphylococcus aureus) (28.6%). Staphylococcus aureus isolated also were sensitive to Erythromycin, Rifampicin, and Cephalothin. Finally, all isolates showed very high rate of resistance against Amoxicillin, ampicillin and penicillin G.

Chlorpromazine-impregnated catheters as a potential strategy to control biofilm-associated urinary tract infections

2019 ◽  
Vol 14 (12) ◽  
pp. 1023-1034 ◽  
Author(s):  
José JC Sidrim ◽  
Bruno R Amando ◽  
Francisco IF Gomes ◽  
Marilia SMG do Amaral ◽  
Paulo CP de Sousa ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Klebsiella Pneumoniae ◽  
Urinary Tract Infections ◽  
Proteus Mirabilis ◽  
Biofilm Formation ◽  
Antibiofilm Activity ◽  
Potential Strategy ◽  
Tract Infections

Aim: This study proposes the impregnation of Foley catheters with chlorpromazine (CPZ) to control biofilm formation by Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae. Materials & methods: The minimum inhibitory concentrations (MICs) for CPZ and the effect of CPZ on biofilm formation were assessed. Afterward, biofilm formation and the effect of ciprofloxacin and meropenem (at MIC) on mature biofilms grown on CPZ-impregnated catheters were evaluated. Results: CPZ MIC range was 39.06–625 mg/l. CPZ significantly reduced (p < 0.05) biofilm formation in vitro and on impregnated catheters. In addition, CPZ-impregnation potentiated the antibiofilm activity of ciprofloxacin and meropenem. Conclusion: These findings bring perspectives for the use of CPZ as an adjuvant for preventing and treating catheter-associated urinary tract infections.

Sign in / Sign up

Export Citation Format

Share Document