Optimization of ICP-MS analytical method for determination of low cadmium content in xylem sap of Ricinus communis

2021 ◽  
Author(s):  
Noor Fitri ◽  
Buchari
Keyword(s):  
Analytical Method ◽  
Ricinus Communis ◽  
Xylem Sap ◽  
Cadmium Content ◽  
Icp Ms

Determination of major to trace elements in metallic materials based on the solid mixing calibration method using multiple spot-laser ablation-ICP-MS

2019 ◽  
Vol 34 (9) ◽  
pp. 1794-1799 ◽  
Author(s):  
Yoshiki Makino ◽  
Yasuo Kuroki ◽  
Takafumi Hirata
Keyword(s):  
Trace Elements ◽  
Laser Ablation ◽  
Analytical Method ◽  
Calibration Method ◽  
Metallic Materials ◽  
Icp Ms ◽  
Multiple Spot

We have developed a new analytical method for the determination of major to trace elements in metallic materials using multiple spot laser ablation (msLA)-ICP-MS.

scholarly journals Fast and Simple Analytical Method for Direct Determination of Total Chlorine Content in Polyglycerol by ICP-MS

Molecules ◽  
2018 ◽  
Vol 23 (2) ◽  
pp. 487 ◽  
Author(s):  
Agata Jakóbik-Kolon ◽  
Andrzej Milewski ◽  
Piotr Dydo ◽  
Magdalena Witczak ◽  
Joanna Bok-Badura
Keyword(s):  
Analytical Method ◽  
Direct Determination ◽  
Chlorine Content ◽  
Simple Analytical Method ◽  
Icp Ms

scholarly journals Interference-free determination of Ca in ultrapure water, concentrated acids and hydrogen peroxide using isotope dilution, ICP-MS and CH3F as a reaction gas

2017 ◽  
Vol 5 ◽  
Author(s):  
Raquel Cardoso Machado ◽  
Maite Aramendía ◽  
Ana Rita A. Nogueira ◽  
Martin Resano
Keyword(s):  
Hydrogen Peroxide ◽  
Isotope Dilution ◽  
Analytical Method ◽  
Isotopic Dilution ◽  
Ultrapure Water ◽  
Dynamic Reaction ◽  
Dynamic Reaction Cell ◽  
Reaction Cell ◽  
Icp Ms

An analytical method was developed for Ca determination in ultrapure water, concentrated acids and hydrogen peroxide by ICP-MS, using CH3F as reaction gas in the dynamic reaction cell (DRC) and isotopic dilution (ID) as strategy of calibration for improve the accuracy and allow interference- free Ca determination.

Determination of Cl, Br and I in granola: Development of an accurate analytical method using ICP-MS

2020 ◽  
pp. 128677
Author(s):  
Gabriel T. Druzian ◽  
Mariele S. Nascimento ◽  
Uillian M.F.M. Cerqueira ◽  
Cleber G. Novaes ◽  
Marcos A. Bezerra ◽  
...  
Keyword(s):  
Analytical Method ◽  
Icp Ms

Elemental Impurities Determination by ICP-AES / ICP-MS: A review of Theory, Interpretation of Concentration Limits, Analytical Method Development Challenges and Validation Criterion for Pharmaceutical Dosage Forms

2020 ◽  
Vol 16 (4) ◽  
pp. 392-403
Author(s):  
Lakshmi Narasimha Rao Katakam ◽  
Hassan Y. Aboul-Enein
Keyword(s):  
Analytical Method ◽  
Method Development ◽  
Drug Product ◽  
Dosage Forms ◽  
Drug Substance ◽  
Individual Element ◽  
Pharmaceutical Dosage Forms ◽  
Elemental Impurities ◽  
Icp Ms

: Inductively coupled plasma is a new technique employed for the determination of elemental impurities in pharmaceutical ingredients viz. raw materials, drug substance, and drug product dosage forms. New US FDA and EMA regulations came into effect from Jan 2018 as industry standard requirements for the determination of inorganic elemental impurities using ICP-OES/AES or ICP-MS analytical techniques. The method development was optimized for the determination of the listed elements as per USP <232> <233> elemental impurities-limits and procedures. It also demonstrates the validation of the method and verification/transfer of the method which also provides an insight into the presence of free elemental atomics of the gaseous form of the sample (drug substance, drug product or excipients), thus helping in determining the concentration of the element of interest. Also, the regulatory guidance is very general and does not explain the sample specifications for the individual element concentrations. Thus, this review emphasizes the routine instrumental maintenance, analytical method development challenges, trends in the performance of analytical method validation and verification/ transfer activities of the various pharmaceutical dosage forms outlined with acceptance criterion.

scholarly journals Multielemental Screening and Analytical Method Validation for Determination of Elemental Impurity in Sucroferric Oxyhydroxide by Using (ICP-MS)

2021 ◽  
pp. 273-280
Author(s):  
Vikas Kumar Singh ◽  
Santosh Kumar Verma ◽  
Sudhanshu Ranjan Swain
Keyword(s):  
Standard Deviation ◽  
Relative Standard Deviation ◽  
Analytical Method ◽  
Drug Product ◽  
Individual Element ◽  
Elemental Impurities ◽  
Acceptable Range ◽  
Icp Ms ◽  
Relative Standard

A highly selective, specific, precise sensitive and reliable ICPMS method has been developed and validated by using ICP-MS for the determination of multielement in Sucroferric oxyhydroxide. The described ICP-MS method provides specific detection and quantification of minor and trace elements from 0.3J(30%) to 2J(200%) of its individual specification of each element i.e Ag, As, Au, Ba, Cd, Co, Cr, Cu, Hg, Ir, Li, Mo, Ni, Os, Pb, Pd, Pt, Rh, Ru, Sb, Se, Sn, Tl,  and V.The analytical method found to be Linear for each individual element with working concentration range from 30%, 50%, 100%, 150% and 200% i.e 0.3J, 0.5J, 1J, 1.5J and 2J with correlation coefficient not less than 0.990.The % recoveries of elemental impurities of each individual elements at three different concentrations with spiking in samples were found to be an acceptable range as 70% to 150%.The method was found to be precise and robust and its relative standard deviation was below 20%.The actual observed relative standard deviation in Precision was found to be in an acceptable range. Therefore developed method can be use for routine quantitative analysis of elemental impurities like Ag, As, Au, Ba, Cd, Co, Cr, Cu, Hg, Ir, Li, Mo, Ni, Os, Pb, Pd, Pt, Rh, Ru, Sb, Se, Sn, Tl, and V to ensure the quality of drug product.

Sign in / Sign up

Export Citation Format

Share Document