PEG-600: Greensolvent for synthesis of pyrazolo[5,1-c]thieno[3,4-e][1,2,4]triazin-6-amine

2021 ◽  
Author(s):  
Srinivasa Reddy Bireddy ◽  
Venkata Ramana Reddy Chittireddy ◽  
Laxminarayana Eppakayala
Keyword(s):  
Peg 600

scholarly journals Uncommon biphasic behaviour induced by very high metal ion concentrations in HCl/H2O/[P44414]Cl and HCl/H2O/PEG-600 systems

2020 ◽  
Vol 22 (40) ◽  
pp. 23226-23236
Author(s):  
Eris Sinoimeri ◽  
Victor Maia Fernandes ◽  
Jérôme Cognard ◽  
Jorge Fernando Brandão Pereira ◽  
Lenka Svecova ◽  
...  
Keyword(s):  
Metal Ion ◽  
Ion Concentrations ◽  
System P ◽  
High Metal ◽  
Very High ◽  
Peg 600

Large amounts of Fe(iii) or Fe(ii) strongly modify the biphasic behavior of the system P44414Cl/HCl/H2O while large amounts of Fe(iii) induce a biphasic regime for the mixture PEG-600/HCl/H2O.

α-Fe2O3 nanoplates: PEG-600 assisted hydrothermal synthesis and formation mechanism

2011 ◽  
Vol 509 (3) ◽  
pp. 885-890 ◽  
Author(s):  
Guo-Ying Zhang ◽  
Yan-Yan Xu ◽  
Dong-Zhao Gao ◽  
Ya-Qiu Sun
Keyword(s):  
Hydrothermal Synthesis ◽  
Formation Mechanism ◽  
Peg 600

scholarly journals The Effect of Manufacturing Methods and Different Shapes on the Release Pattern of Diclofenac Sodium Matrix Tablet

1970 ◽  
Vol 2 (2) ◽  
pp. 76-80
Author(s):  
Tajnin Ahmed ◽  
Muhammad Shahidul Islam ◽  
Tasnuva Haque ◽  
Mohammad Abusyed
Keyword(s):  
Sustained Release ◽  
Release Rate ◽  
Diclofenac Sodium ◽  
Matrix Tablets ◽  
Wet Granulation ◽  
Matrix Tablet ◽  
Direct Compression ◽  
Compression Method ◽  
Release Pattern ◽  
Peg 600

In the present study sustained release diclofenac sodium matrix tablets were prepared using Kollidon SR polymer. Hydroxypropyl methylcellulose (HPMC 15 cps) and poly ethylene glycol (PEG-600) polymers respectively were used in formulating tablets prepared by direct compression and wet granulation methods. The polymers were used to explore the release pattern of the drug into the dissolution media. The tablets were also prepared in various shapes (caplet oval, round oval and flat oval). A comparatively higher release rate of drug was obtained from the polymer HPMC 15 cps at 10% concentration for directly compressed matrix tablet than those containing 20% of HPMC after a definite period of time. In wet granulation process, 10% PEG-600 containing tablets showed a better release than those containing 20% PEG. The drug release was also found to be sustained in case of wet granulation method than that of the direct compression method. Again the caplet shaped tablets in case of direct compression method showed better release rate of drug than those of the round oval and flat oval shaped tablets. Thus the result of this study shows that the proper selection of the percentage of polymer and the suitable shape of tablet and proper manufacturing method can provide a greater opportunity in designing sustained release dosage forms. Key words: Matrix tablet; release pattern; direct compression; wet granulation; PEG 600; Kollidon SR.DOI: 10.3329/sjps.v2i2.5828Stamford Journal of Pharmaceutical Sciences Vol.2(2) 2009: 76-80

scholarly journals Synthesis of 14-Substituted-14H-Dibenzo[a,j]Xanthene Derivatives in Presence of Effective Synergetic Catalytic System Bleaching Earth Clay and PEG-600

Catalysts ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1294
Author(s):  
Sandeep T. Atkore ◽  
Giribala M. Bondle ◽  
Pranita V. Raithak ◽  
Vinod T. Kamble ◽  
Ravi Varala ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Catalytic System ◽  
Present Method ◽  
Condensation Reaction ◽  
Bleaching Earth ◽  
Product Yield ◽  
Xanthene Derivatives ◽  
Peg 600

The synthesis of 14-aryl 14H-dibenzo[a,j]xanthenes is achieved by a simple condensation reaction between β-naphthol with aryl or alkyl aldehydes in an effective synergetic catalytic system created by combining basic bleaching earth clay and PEG-600. The advantages of the present method include catalyst recyclability, superior product yield, a shorter reaction time and the avoidance of hazardous reagents. Synthesized xanthene derivatives were also screened for their antibacterial activity against Staphylococcus aureus (MTCC 96) and Pseudomonas aeruginosa (Wild).

Effect of alumina on the performance and characterization of cross-linked PVA/PEG 600 blended membranes for CO2/N2 separation

2019 ◽  
Vol 210 ◽  
pp. 627-635 ◽  
Author(s):  
Muhammad Rizwan Dilshad ◽  
Atif Islam ◽  
Usamah Hamidullah ◽  
Fahd Jamshaid ◽  
Adnan Ahmad ◽  
...  
Keyword(s):  
Peg 600

Green Synthesis, Molecular Docking Studies and Anticancer Effects of 3-Methyl-2-(((1-Methyl-1H-Benzo[d]imidazol-2-yl) thio) Methyl) Quinazolin-4(3H)-One

2021 ◽  
Vol 25 (7) ◽  
pp. 138-146
Author(s):  
E. Laxminarayana ◽  
P. Bhasker ◽  
D. Ramesh ◽  
Md. Rafeeq ◽  
B. Srinivasa Reddy
Keyword(s):  
Acetic Acid ◽  
Molecular Docking ◽  
Green Synthesis ◽  
Docking Studies ◽  
Chemotherapeutic Agents ◽  
Green Solvent ◽  
Anticancer Effects ◽  
Best Fit ◽  
Green Conditions ◽  
Peg 600

compound 2-((1H-benzo[d]imidazol-2-yl)thio)acetic acid (1) with o-aminobenzamide (2) gave compound (2-[1-(1H-benzimidazol-2-yl)-ethylsulfanyl]-3H-quinazolin-4-one (3). 3 could also be syntehsized by an alternative two routes scheme 2 and scheme 3. It appears from scheme 3 that it is giving good yields under green and eco-friendly conditions using PEG-600 (polyethylent glycol). Compound 10 was synthesized in two routes scheme4 and scheme 5. It appears from Route B (Scheme 4) that it is giving good yields: alkylation followed by oxidation in route A followed by alkylation in PEG-600 used as a green solvent. The total sequence of reactions has been carried out using eco-friendly and green conditions. Further, anticancer activity was carried out by using docking studies and binding conformation of active compounds of 3, 8, 9 and 10. The results show that 3 and 9 have potential to be developed as chemotherapeutic agents and compounds 3, 9 molecule showed best fit, potent dock score when compared with doxorubicin.

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