The effectiveness of silver diamine fluoride in inhibiting dentine caries activity on primary teeth

2021 ◽  
Author(s):  
Risqa Rina Darwita ◽  
Faradina Siti Zahra ◽  
Irwina Nuryanti Husna ◽  
Melissa Adiatman ◽  
Gita Ariffa Sjarkawi
Keyword(s):  
Primary Teeth ◽  
Silver Diamine Fluoride ◽  
Caries Activity

Effectiveness of Silver Diamine Fluoride in Preventing Occlusal Caries in Primary Teeth of Preschool Children: a Study Protocol for a Randomized Clinical Trial (Preprint)

2021 ◽  
Author(s):  
Duangporn Duangthip ◽  
SHUYANG HE ◽  
Sherry Shiqian Gao ◽  
Chun Hung Chu ◽  
Edward Chin Man Lo
Keyword(s):  
Logistic Regression ◽  
Preschool Children ◽  
Oral Health ◽  
Primary Teeth ◽  
Controlled Trial ◽  
Public Health Problem ◽  
Placebo Control ◽  
Occlusal Caries ◽  
Silver Diamine Fluoride ◽  
Occlusal Surfaces

BACKGROUND Tooth decay is a significant public health problem globally. The caries-arrest effectiveness of 38% silver diamine fluoride (SDF) has been well documented. However, information on the caries preventive effect of SDF on primary teeth is insufficient. OBJECTIVE The aim of this trial is to investigate the effectiveness of semi-annual application of 38% SDF and that of 5% sodium fluoride (NaF) varnish when compared to placebo control in preventing occlusal caries in primary molars of preschool children over 30 months. METHODS This three-arm, parallel design, double-blind, randomised controlled trial involves 791 preschool children. Children are randomly allocated to receive one of the three interventions as follows; Group 1) 38% SDF, Group 2) 5% NaF varnish, and Group 3) placebo control with tonic water. The intervention and dental examination will be carried out every 6 months. A parent-administered questionnaire including the children’s demographic background and oral health-related behaviours has been collected at baseline. Follow-up examinations to detect new caries development will be conducted every 6 months by a masked examiner. Caries development will be diagnosed at the cavitation level. Chi-square tests and logistic regression analyses will be adopted. A two-level logistic regression analysis will be performed to investigate the effects of the study interventions and other potential confounding factors on the development of occlusal caries. RESULTS Result: To date, a total of 791 children are participating in the study. CONCLUSIONS If SDF application is more effective than NaF varnish in preventing caries on occlusal surfaces of primary teeth, it can be a preferred choice for caries prevention in a kindergarten-based program. Results of this trial will provide valuable clinical evidence for the development of oral health strategies and policy on promotion of child oral health CLINICALTRIAL ClinicalTrials.gov NCT05084001

scholarly journals “It’s really no more difficult than putting on fluoride varnish”: A qualitative exploration of dental professionals’ views of silver diamine fluoride for the management of carious lesions in children

2020 ◽  
Author(s):  
Nassar Seifo ◽  
Heather Cassie ◽  
John Radford ◽  
Nicola Innes
Keyword(s):  
Primary Teeth ◽  
Application Process ◽  
Invasive Treatment ◽  
Silver Diamine Fluoride ◽  
Non Invasive ◽  
Parents And Children ◽  
Carious Lesions ◽  
Framework Approach ◽  
The Uk ◽  
Dental Professionals

Abstract Background: Despite evidence that Silver Diamine Fluoride (SDF) can be effective in managing carious lesions in primary teeth, there is still limited use the UK. This study explored dental professionals’ views and experiences of using SDF for managing carious lesions in children. In addition, it explored what they perceived to be the advantages, disadvantages, barriers and enablers to the use of SDF in practice.Methods: Fifteen semi-structured face-to-face or over-the-phone interviews were conducted with 14 dental professionals from NHS Tayside and NHS Grampian in Scotland. Interviews were transcribed verbatim, coded and analysed using a framework approach.Results: Thirteen of 14 dental professionals interviewed were familiar with, or had some existing knowledge of, SDF. Four had used it to treat patients. The majority of participants thought that the main advantage of SDF was that it required minimal patient cooperation. Silver diamine fluoride was also perceived as a simple, pain-free and non-invasive treatment approach that could help acclimatise children to the dental environment. However, SDF-induced black staining of arrested carious lesions was most commonly reported as the main disadvantage and greatest barrier to using it in practice. Participants believed that this discolouration would concern some parents who may fear that the black appearance may instigate bullying at school and that others may judge parents as neglecting their child’s oral health. Participants thought that education of clinicians about SDF use and information sheets for parents would enhance the uptake of SDF in dental practice. Participants believed that younger children might not be as bothered by the discolouration as older ones and they anticipated greater acceptance of SDF for posterior primary teeth by both parents and children.Conclusion: Dental professionals were aware that SDF can be used for arresting carious lesions. They pointed out that the staining effect of carious lesions is a major disadvantage that could be a barrier for many parents. Participants considered the application process to be simple and non-invasive and requires a minimum level of child’s cooperation. Participants appreciated the potentials of SDF in paediatric dentistry and suggested actions that could help overcome the barriers they highlighted.

scholarly journals “It’s really no more difficult than putting on fluoride varnish”: A qualitative exploration of dental professionals’ views of silver diamine fluoride for the management of carious lesions in children

2020 ◽  
Author(s):  
Nassar Seifo ◽  
Heather Cassie ◽  
John Radford ◽  
Nicola Innes
Keyword(s):  
Primary Teeth ◽  
Application Process ◽  
Invasive Treatment ◽  
Silver Diamine Fluoride ◽  
Non Invasive ◽  
Parents And Children ◽  
Carious Lesions ◽  
Patient Cooperation ◽  
The Uk ◽  
Dental Professionals

Abstract BackgroundDespite evidence that Silver Diamine Fluoride (SDF) can be effective in managing carious lesions in primary teeth, the use of SDF in the UK remains limited. This study explored dental professionals’ views and experiences of using SDF for managing carious lesions in children. In addition, it explored what they perceived to be the advantages, disadvantages, barriers and enablers to the use of SDF in practice.MethodsFifteen semi-structured face-to-face or over-the-phone interviews were conducted with 14 dental professionals from NHS Tayside and NHS Grampian in Scotland. Interviews were transcribed verbatim, coded and analysed using a thematic approach.ResultsThirteen of 14 dental professionals interviewed were familiar with, or had some existing knowledge of, SDF. Four had used it to treat patients. The majority of participants thought that the main advantage of SDF was that it required minimal patient cooperation. SDF was also perceived as a simple, pain-free and non-invasive treatment approach that could help acclimatise children to the dental environment. However, SDF-induced black staining of arrested carious lesions was most commonly reported as the main disadvantage and greatest barrier to using it in practice. Participants believed that this discolouration would concern some parents who may fear that the black appearance may instigate bullying at school and that others may judge parents as neglecting their child’s oral health. Participants thought that education of clinicians about SDF use and information sheets for parents would enhance the uptake of SDF in dental practice. Participants believed that younger children might not be as bothered by the discolouration as older ones and they anticipated greater acceptance of SDF for posterior primary teeth by both parents and children.ConclusionDental professionals were aware that SDF can be used for arresting carious lesions. They pointed out that the staining effect of carious lesions is a major disadvantage that could be a barrier for many parents. Participants considered the application process to be simple and non-invasive and requires a minimum level of child cooperation. Participants appreciated the potential of SDF in paediatric dentistry and suggested actions that could help overcome the barriers they highlighted.

Efficacy of Silver Diamine Fluoride for Arresting Caries Treatment

2009 ◽  
Vol 88 (7) ◽  
pp. 644-647 ◽  
Author(s):  
R. Yee ◽  
C. Holmgren ◽  
J. Mulder ◽  
D. Lama ◽  
D. Walker ◽  
...  
Keyword(s):  
Tannic Acid ◽  
Null Hypothesis ◽  
Primary Teeth ◽  
A Priori ◽  
Additional Benefit ◽  
Single Application ◽  
Silver Diamine Fluoride ◽  
Restorative Treatment ◽  
Caries Treatment ◽  
Untreated Dental Caries

Arresting Caries Treatment (ACT) has been proposed to manage untreated dental caries in children. This prospective randomized clinical trial investigated the caries-arresting effectiveness of a single spot application of: (1) 38% silver diamine fluoride (SDF) with tannic acid as a reducing agent; (2) 38% SDF alone; (3) 12% SDF alone; and (4) no SDF application in primary teeth of 976 Nepalese schoolchildren. The a priori null hypothesis was that the different treatments have no effect in arresting active cavitated caries. Only the single application of 38% SDF with or without tannic acid was effective in arresting caries after 6 months (4.5 and 4.2 mean number of arrested surfaces; p < 0.001), after 1 year (4.1 and 3.4; p < 0.001), and after 2 years (2.2 and 2.1; p < 0.01). Tannic acid conferred no additional benefit. ACT with 38% SDF provides an alternative when restorative treatment for primary teeth is not an option.

Topical Effect of Silver Diamine Fluoride in Arresting Dental Caries in Primary Teeth

2019 ◽  
Vol 10 (5) ◽  
pp. 1285
Author(s):  
Mohammed Qays Mahmood Fahmi ◽  
Maha Jamal Abbas ◽  
Lubna Abdulelah Abdulrahman Almallah
Keyword(s):  
Dental Caries ◽  
Primary Teeth ◽  
Silver Diamine Fluoride

scholarly journals Randomized Clinical Trial of 12% and 38% Silver Diamine Fluoride Treatment

2017 ◽  
Vol 97 (2) ◽  
pp. 171-178 ◽  
Author(s):  
M.H.T. Fung ◽  
D. Duangthip ◽  
M.C.M. Wong ◽  
E.C.M. Lo ◽  
C.H. Chu
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Primary Teeth ◽  
Intervention Group ◽  
Silver Diamine Fluoride ◽  
Fluoride Treatment ◽  
Group 4 ◽  
Decayed Tooth ◽  
Tooth Surfaces ◽  
Group 2

This 30-mo randomized clinical trial compared the effectiveness of 2 concentrations (12% or 38%) of silver diamine fluoride (SDF) and 2 periodicity of application (once or twice a year) in arresting cavitated dentin caries in primary teeth. Children aged 3 to 4 y who had at least 1 active cavitated caries lesion were enrolled and randomly allocated into 4 groups for intervention. Group 1 had 12% SDF applied annually (every 12 mo), group 2 had 12% SDF applied semiannually (every 6 mo), group 3 had 38% SDF applied annually, and group 4 had 38% SDF applied semiannually. Clinical examinations were performed semiannually in kindergarten by a single examiner to investigate whether the SDF-treated caries became arrested. A total of 888 children with 4,220 decayed tooth surfaces received SDF application at baseline, and 799 (90.0%) children with 3,790 surfaces (89.8%) were evaluated at the 30-mo examination. The caries arrest rates were 55.2%, 58.6%, 66.9%, and 75.7% for groups 1, 2, 3, and 4, respectively ( P < 0.001). Caries treated with 38% SDF had a higher chance of becoming arrested than those treated with 12% SDF (odds ratio [OR], 1.98; 95% confidence interval [CI], 1.51–2.60, P < 0.001). The interaction between frequency of SDF application and visible plaque index (VPI) score was significant ( P = 0.017). Among those children who received annual SDF application, children with a higher VPI score had a lower chance to have their caries become arrested (OR, 0.59, 95% CI, 0.49–0.72). In conclusion, SDF at a concentration of 38% is more effective than that of 12% in arresting active caries in primary teeth. For children with poor oral hygiene, caries arrest rate of SDF treatment can be increased by increasing the frequency of application from annually to semiannually ( ClinicalTrials.gov NCT02385474).

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