Numerical research of mechanical behavior of biological tissues under uniaxial compression/tension

2020 ◽  
Author(s):  
A. Chirkov ◽  
G. M. Eremina ◽  
A. Yu. Smolin ◽  
M. O. Eremin
Keyword(s):  
Mechanical Behavior ◽  
Uniaxial Compression ◽  
Biological Tissues ◽  
Numerical Research

A Novel Compression Tester for Detecting Anisotropy in Very Soft Biological Tissues

2012 ◽  
Author(s):  
Roy Wang ◽  
Rudolph L. Gleason
Keyword(s):  
Adipose Tissue ◽  
Mechanical Behavior ◽  
Uniaxial Compression ◽  
Material Properties ◽  
Soft Tissues ◽  
Tensile Tests ◽  
Biological Tissues ◽  
Compression Tests ◽  
Anisotropic Behavior ◽  
Soft Biological Tissues

Quantifying the mechanical behavior of very soft tissues (VST) is important when studying responses to injury or designing therapeutic devices; fat, brain, or liver being examples of such tissues. VST can have poor suture retention or clamp holding strength, making tensile tests difficult. As a result, uniaxial compression tests are typically the preferred choice to quantify the mechanical behavior. In these tests, isotropy is generally assumed and measuring the deformation in only one direction is needed if the material is considered incompressible [13]. In this study we present a novel testing apparatus for use on VST under uniaxial compression that can detect anisotropic behavior of the tissue if present. We validate the tester using cardiac adipose tissue and isotropic rubber as the control. Understanding the directional behavior of the tissue is important since anisotropy would require testing in multiple directions to fully characterize the material properties.

scholarly journals Mechanical behavior of Ti-6Al-4V lattice-walled tubes under uniaxial compression

2021 ◽  
Author(s):  
Gen-zhu Feng ◽  
Jing Wang ◽  
Xin-yuan Li ◽  
Li-jun Xiao ◽  
Wei-dong Song
Keyword(s):  
Mechanical Behavior ◽  
Uniaxial Compression

Modeling the Large Deformation and Microstructure Evolution of Nonwoven Polymer Fiber Networks

2018 ◽  
Vol 86 (1) ◽  
Author(s):  
Mang Zhang ◽  
Yuli Chen ◽  
Fu-pen Chiang ◽  
Pelagia Irene Gouma ◽  
Lifeng Wang
Keyword(s):  
Mechanical Properties ◽  
Aspect Ratio ◽  
Mechanical Behavior ◽  
Large Deformation ◽  
Biological Tissues ◽  
High Porosity ◽  
Polymer Fiber ◽  
Fiber Networks ◽  
Fiber Aspect Ratio ◽  
Network Microstructure

The electrospinning process enables the fabrication of randomly distributed nonwoven polymer fiber networks with high surface area and high porosity, making them ideal candidates for multifunctional materials. The mechanics of nonwoven networks has been well established for elastic deformations. However, the mechanical properties of the polymer fibrous networks with large deformation are largely unexplored, while understanding their elastic and plastic mechanical properties at different fiber volume fractions, fiber aspect ratio, and constituent material properties is essential in the design of various polymer fibrous networks. In this paper, a representative volume element (RVE) based finite element model with long fibers is developed to emulate the randomly distributed nonwoven fibrous network microstructure, enabling us to systematically investigate the mechanics and large deformation behavior of random nonwoven networks. The results show that the network volume fraction, the fiber aspect ratio, and the fiber curliness have significant influences on the effective stiffness, effective yield strength, and the postyield behavior of the resulting fiber mats under both tension and shear loads. This study reveals the relation between the macroscopic mechanical behavior and the local randomly distributed network microstructure deformation mechanism of the nonwoven fiber network. The model presented here can also be applied to capture the mechanical behavior of other complex nonwoven network systems, like carbon nanotube networks, biological tissues, and artificial engineering networks.

ANTICYTOSKELETAL DRUGS AND TIME CULTURE EFFECTS UPON THE MECHANICAL BEHAVIOR OF DERMAL EQUIVALENT TISSUE SUBMITTED TO UNCONFINED COMPRESSION LOADING

2008 ◽  
Vol 08 (03) ◽  
pp. 339-352 ◽  
Author(s):  
S. RAMTANI ◽  
D. GEIGER
Keyword(s):  
Mechanical Behavior ◽  
Internal State ◽  
Skin Grafting ◽  
Biological Tissues ◽  
Matrix Remodeling ◽  
Unconfined Compression ◽  
Compression Loading ◽  
Dermal Equivalent ◽  
Variable Approach ◽  
Time Culture

The dermal equivalent (DE), a dermis substitute consisting of human skin fibroblasts growing into a three-dimensional collagen matrix, is extensively used in many applications: wound-healing response, pharmacological studies, skin grafting, fibroblast proliferation and migration, extracellular matrix remodeling, and efficacy of cosmetic products. The widespread growth of numerical modeling in biomechanical research has placed a heightened emphasis on accurate material property data for soft biological tissues, in particular for equivalent dermis which has not been so thoroughly investigated. Under unconfined compression loading, the effects of the strain rate, time culture, and cytoskeleton-disrupting agents are experimentally investigated. In order to model the observed mechanical behavior of the DE under the above conditions, the internal state variable approach is adopted for finite deformation viscoelasticity and the optimized material parameters are identified with respect to the stated thermodynamic restriction (i.e. positive viscous dissipation).

Mechanical Behavior of 2D C/SiC Composites at Elevated Temperatures under Uniaxial Compression

2011 ◽  
Vol 462-463 ◽  
pp. 1-6 ◽  
Author(s):  
Tao Suo ◽  
Yu Long Li ◽  
Ming Shuang Liu
Keyword(s):  
Compressive Strength ◽  
High Temperature ◽  
Carbon Fiber ◽  
Mechanical Behavior ◽  
Uniaxial Compression ◽  
Room Temperature ◽  
Elevated Temperatures ◽  
Carbon Matrix ◽  
Structural Applications ◽  
Sic Composites

As Carbon-fiber-reinforced SiC-matrix (C/SiC) composites are widely used in high-temperature structural applications, its mechanical behavior at high temperature is important for the reliability of structures. In this paper, mechanical behavior of a kind of 2D C/SiC composite was investigated at temperatures ranging from room temperature (20C) to 600C under quasi-static and dynamic uniaxial compression. The results show the composite has excellent high temperature mechanical properties at the tested temperature range. Catastrophic brittle failure is not observed for the specimens tested at different strain rates. The compressive strength of the composite deceases only 10% at 600C if compared with that at room temperature. It is proposed that the decrease of compressive strength of the 2D C/SiC composite at high temperature is influenced mainly by release of thermal residual stresses in the reinforced carbon fiber and silicon carbon matrix and oxidation of the composite in high temperature atmosphere.

Mechanical Behavior of Aluminum Foam Under Uniaxial Compression

2006 ◽  
pp. 73-82
Author(s):  
B. Kriszt ◽  
B. Foroughi ◽  
A. Kottar ◽  
H.P. Degischer
Keyword(s):  
Mechanical Behavior ◽  
Uniaxial Compression ◽  
Aluminum Foam

On the Ability of Structural and Phenomenological Hyperelastic Models to Predict the Mechanical Behavior of Biological Tissues Submitted to Multiaxial Loadings

2012 ◽  
Author(s):  
Mathieu Nierenberger ◽  
Yves Rémond ◽  
Saïd Ahzi
Keyword(s):  
Experimental Data ◽  
Mechanical Behavior ◽  
Strain Energy ◽  
Soft Tissues ◽  
Least Squares Method ◽  
Biological Tissues ◽  
Physical Parameters ◽  
Cauchy Stress ◽  
Specific Loading ◽  
Hyperelastic Models

Medical surgery is currently rapidly improving and requires modeling faithfully the mechanical behavior of soft tissues. Various models exist in literature; some of them created for the study of biological materials, and others coming from the field of rubber mechanics. Indeed biological tissues show a mechanical behavior close to the one of rubbers. But while building a model, one has to keep in mind that its parameters should be loading independent and that the model should be able to predict the behavior under complex loading conditions. In addition, keeping physical parameters seems interesting since it allows a bottom up approach taking into account the microstructure of the material. In this study, the authors consider different existing hyperelastic models based on strain energy functions and identify their coefficients successively on single loading stress-stretch curves. The experimental data used, come from a paper by Zemanek dated 2009 and concerning uniaxial, equibiaxial and plane tension tests on porcine arterial walls taken in identical experimental conditions. To achieve identification, the strain energy function of each model is derived differently to provide an expression of the Cauchy stress associated to each loading case. Firstly the parameters of each model are identified on the uniaxial tension curve using a least squares method. Then, keeping the obtained parameters, predictions are made for the two other loading cases (equibiaxial and plane tension) using the associated expressions of stresses. A comparison of these predictions with experimental data is done and allows evaluating the predictive capabilities of each model for the different loading cases. A similar approach is used after swapping the loading types. Since the predictive capabilities of the models are really dependent on the loading chosen to determine their parameters, another type of identification procedure is set up. It consists in adding the residues over the three loading cases during identification. This alternative identification method allows a better agreement between each model and the various types of experiments. This study evaluated the ability of some classical hyperelastic models to be used for a predictive scope after being identified on a specific loading type. Besides it brought to light some existing models which can describe at best the mechanical behavior of biological tissues submitted to various loadings.

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