Lagrangian study of the particle transport past a lateral, open-channel cavity

2021 ◽  
Vol 33 (1) ◽  
pp. 013303
Author(s):  
L. Engelen ◽  
C. Perrot-Minot ◽  
E. Mignot ◽  
N. Rivière ◽  
T. De Mulder
Keyword(s):  
Particle Transport ◽  
Open Channel ◽  
Lagrangian Study

Open-channel-block induced by the neurotransmitter glycine in homomeric alpha1-GlyR and heteromeric alpha1/beta1- GlyR

2008 ◽  
Vol 35 (S 01) ◽  
Author(s):  
Y.P Song ◽  
F Schlesinger ◽  
S Petri ◽  
R Dengler ◽  
K Krampfl
Keyword(s):  
Open Channel ◽  
Channel Block ◽  
Open Channel Block

The Influence of Ascorbic Acid on Platelet Structure and Function

1975 ◽  
Vol 34 (01) ◽  
pp. 050-062
Author(s):  
Dale H Cowan ◽  
Richard C Graham ◽  
Patricia Shook ◽  
Ronda Griffin
Keyword(s):  
Ascorbic Acid ◽  
Open Channel ◽  
Channel System ◽  
Short Intervals ◽  
Platelet Survival ◽  
Artifactual Changes ◽  
Survival Studies ◽  
And Function ◽  
Induced Aggregation ◽  
Platelet Structure

SummaryTo determine the effect on platelet behavior of transient exposure of platelets to ascorbic acid, studies of platelet function and ultrastructure were done before exposure to ascorbic acid at pH 6.5, during exposure to pH 6.5, and after restoration of pH to pre-acidifìcation levels. The effect of ascorbic acid (A. A.) was compared to that of HCl and citric acid (C. A.). ADP- and collagen-induced aggregation of normal platelets were significantly impaired by both A. A. and C. A. but were less affected by HCl. The release of 14C-serotonin was significantly reduced by each agent. The ultra-structure of normal platelets brought to pH 6.5 by A.A. was normal. After neutralization, there was marked dilatation of the open channel system and loss of the disc shape. When platelets were brought to pH 6.5 by A. A., then neutralized, the aggregates which formed after stimulation by ADP or collagen were smaller than normal, the platelets were less closely approximated, and degranulation was less complete. The data show that exposure of platelets to ascorbic acid for short intervals impairs their function when measured after restoration of pH to levels compatible with maximal responses. Platelet survival studies using autologous platelets labelled with 51Cr in the presence or absence of ascorbic acid showed that the recovery of normal platelets was unaffected by ascorbic acid, whereas recovery of platelets from patients with idiopathic thrombocytopenic purpura, idiopathic thrombocythemia, and alcohol-related thrombocytopenia was markedly reduced. The injury resulting from the use of ascorbic acid in preparing platelets for studies of platelet survival in patients with disorders affecting platelets may impair the recovery of the cells, resulting in artifactual changes in the survival studies.

A Study of the Average Flow in Open Channel with Baffle Blocks Distributed Uniformly

10.29007/zx1w ◽  
2018 ◽  
Author(s):  
Dung Tien Tran ◽  
Anh Tuan Le ◽  
Hong Nhung Le ◽  
Viet Hung Ho
Keyword(s):  
Water Level ◽  
Water Depth ◽  
Open Channel ◽  
Block Size ◽  
Average Flow ◽  
Modelling Studies ◽  
Baffle Block

A study of average flow in open channel with baffle blocks distributed uniformly has been considered by using channel with varied slopes. In this article, experimental and modelling studies were introduced when the correlation between the water depth and baffle block size is significant. The objective of the work is to give the rudimentary relations between discharge and water level in the channels. When the water depth is large, the effect of bottom channel friction on the flow is relatively small. This paper also gives applications of the software ‘Telemac-2D’ to simulate the flow under different conditions.

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