scholarly journals Synthesis and study biological activity of new heterocyclic compounds based on sugar

2020 ◽  
Author(s):  
Ehab K. Obaid ◽  
Rahmah H. Abdullah ◽  
Hussein Abdulkadim Hasan ◽  
Najlaa N. Hussein ◽  
Maha A. Khalaf ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds

Synthesis and Biological Potentials of Quinoline Analogues: A Review of Literature

2019 ◽  
Vol 16 (7) ◽  
pp. 653-688 ◽  
Author(s):  
Leena Kumari ◽  
Salahuddin ◽  
Avijit Mazumder ◽  
Daman Pandey ◽  
Mohammad Shahar Yar ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds ◽  
Building Blocks ◽  
Vital Role ◽  
Review Of Literature ◽  
Drug Discovery Process ◽  
Active Compounds ◽  
Lead Compounds ◽  
Synthetic Approaches ◽  
Derivatives Of

Heterocyclic compounds are well known for their different biological activity. The heterocyclic analogs are the building blocks for synthesis of the pharmaceutical active compounds in the organic chemistry. These derivatives show various type of biological activity like anticancer, antiinflammatory, anti-microbial, anti-convulsant, anti-malarial, anti-hypertensive, etc. From the last decade research showed that the quinoline analogs plays a vital role in the development of newer medicinal active compounds for treating various type of disease. Quinoline reported for their antiviral, anticancer, anti-microbial and anti-inflammatory activity. This review will summarize the various synthetic approaches for synthesis of quinoline derivatives and to check their biological activity. Derivatives of quinoline moiety plays very important role in the development of various types of newer drugs and it can be used as lead compounds for future investigation in the field of drug discovery process.

1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions

2014 ◽  
Vol 2014 (16) ◽  
pp. 3289-3306 ◽  
Author(s):  
Antonino Lauria ◽  
Riccardo Delisi ◽  
Francesco Mingoia ◽  
Alessio Terenzi ◽  
Annamaria Martorana ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds ◽  
Dipolar Cycloadditions

Synthesis and biological activity of some more heterocyclic compounds containing benzothiophene moiety

2011 ◽  
Vol 32 (3) ◽  
pp. 235-247 ◽  
Author(s):  
Gadada Naganagowda ◽  
Patchanita Thamyongkit ◽  
Runchana Klai-U-dom ◽  
Waraporn Ariyakriangkrai ◽  
Arithat Luechai ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds

Biological Activity of Some Heterocyclic Compounds Based on Polyol Acetals and their Derivatives

2020 ◽  
Vol 54 (9) ◽  
pp. 909-913
Author(s):  
G. Z. Raskil’dina ◽  
U. Sh. Kuz’mina ◽  
Yu. G. Borisova ◽  
Yu. V. Vakhitova ◽  
S. S. Zlotskii
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds

Oximes of six-membered heterocyclic compounds with two and three heteroatoms. II.* Reactions and biological activity (review)

2010 ◽  
Vol 46 (8) ◽  
pp. 905-930 ◽  
Author(s):  
E. Abele ◽  
R. Abele ◽  
L. Golomba ◽  
J. Višņevska ◽  
T. Beresneva ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds

ChemInform Abstract: Novel Synthesis of Some New Fused/Spiro Heterocyclic Compounds and Their Biological Activity.

ChemInform ◽  
2010 ◽  
Vol 27 (12) ◽  
pp. no-no
Author(s):  
A. K. KHALAFALLAH ◽  
M. A. SELIM ◽  
R. M. ABU EL-HAMD ◽  
M. A. EL-MAGHRABY ◽  
H. A. SOLEIMAN ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds ◽  
Novel Synthesis

ChemInform Abstract: Oximes of Six-Membered Heterocyclic Compounds with Two and Three Heteroatoms. Part 2. Reactions and Biological Activity

ChemInform ◽  
2011 ◽  
Vol 42 (16) ◽  
pp. no-no
Author(s):  
E. Abele ◽  
R. Abele ◽  
L. Golomba ◽  
J. Visnevska ◽  
T. Beresneva ◽  
...  
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds

scholarly journals Synthesis and Antimicrobial Studies of New [Tetrakis (1, 2, 4-Triazole / 1, 3, 4-Oxadiazole / 1, 3, 4-Thiadiazole] [Bis-(Benzene-1, 3, 5-Triyl)] Dioxymethylene Compounds

2020 ◽  
pp. 234-245
Author(s):  
Ahmed Neamah Ayyash
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compounds ◽  
Chemical Structure ◽  
Acid Hydrazide ◽  
Basic Medium ◽  
Tosyl Chloride ◽  
Antimicrobial Studies ◽  
Ft Ir ◽  
Concentrated Sulfuric Acid ◽  
Derivatives Of

     Synthesis of new heterocyclic compounds containing four five-membered rings together was the main goal of this work. The new derivatives of [tetrakis (1,2,4-triazole /1,3,4-thiadiazole /1,3,4-oxadiazole][bis-(benzene-1,3,5-triyl)] dioxymethylene A7-A18 were synthesized by the reaction of [bis-(dimethyl 5-yl-isophthalate)] dioxymethylene compound A1 which was previously prepared from the reaction of 1,2-dibromomethan and dimethyl 5-hydroxyisophthalate, then treated with hydrazine hydrate to yield the corresponding acid hydrazide A2. In the next step, compound A2 was refluxed with 4-substituted isothiocyanate to give substituted thiosemicarbazides A3-A6. The treatment of the latter compounds in basic medium of 2M of NaOH afforded 1,2,4-Triazole derivatives A7-A10. Whereas the reaction of the same compounds with concentrated sulfuric acid gave 1,3,4-thiadiazoles  A11-A14. Furthermore, the new derivatives of 1,3,4-oxadiazole A15-A18 were obtained by the reaction of thiosemicarbazides and tosyl chloride in presence of pyridine. (C. H. N.) elemental analysis, FT-IR, and 1HNMR techniques were used to characterize the chemical structure of some of the new synthesized compounds which also exhibited an important biological activity.

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