scholarly journals Hydrogel of carboxymethyl cellulose and polyvinyl alcohol modified by CuNPs as antibacterial in wound dressing

2020 ◽  
Author(s):  
A. Ponco ◽  
H. Helmiyati
Keyword(s):  
Polyvinyl Alcohol ◽  
Carboxymethyl Cellulose ◽  
Wound Dressing

scholarly journals A Novel Bilayer Propionyl-L-carnitine Loaded Polyvinyl Alcohol/Calcium Alginate/Carboxymethyl Cellulose wound dressing for the treatment of diabetic wounds: an in vitro and in vivo study

2021 ◽  
Author(s):  
Wenjun Jiang ◽  
Zuoyao Huang ◽  
Weixiang Min ◽  
Hao Zhang
Keyword(s):  
Polyvinyl Alcohol ◽  
Carboxymethyl Cellulose ◽  
Wound Dressing ◽  
Calcium Alginate ◽  
Wound Dressings ◽  
Vapor Permeability ◽  
Drying Methods ◽  
Cell Viability Assay ◽  
Diabetic Wounds

Abstract In the current study a drug delivering bilayer porous/nanofibrous wound dressing was developed using a combination of electrospinning and freeze-drying methods. The wound dressings were prepared by lyophilization of 1:1 weight ratios of calcium alginate and carboxymethyl cellulose (CMC) solutions. Drug delivering nanofibrous sheets were fabricated by electrospinning of polyvinyl alcohol (PVA) solution incorporated with 1%,3%,5%, and 10% of Propionyl-L-carnitine. The dressings were studied regarding their microstructure, swelling capacity, mechanical strength, surface wettability, water vapor permeability, drug release profile, in vitro degradation, cell viability assay, hemocompatibility, porosity measurement, microbial penetration assay, and protein adsorption assay. Based on in vitro studies, PVA sheets loaded with 5% Propionyl-L-carnitine was chosen for the preparation of wound dressings. The healing potential of the produced constructs was studied in rat model of diabetic wound. Our results showed that the drug delivering dressings demonstrated significantly higher wound closure and better histological regeneration compared to drug free constructs and sterile gauze. Our results suggest potential applicability of Propionyl-L-carnitine delivering Calcium Alginate/CMC/PVA dressing for the treatment of diabetic wounds in clinic.

Enhanced functional properties of biodegradable Polyvinyl alcohol /carboxymethyl cellulose (PVA/CMC) composite films reinforced with L-alanine surface modified CuO nanorods

2021 ◽  
Author(s):  
Yamanappagouda Amaregouda ◽  
Kantharaju Kamanna ◽  
Tilak Gasti ◽  
Vijay Kumbar
Keyword(s):  
Polyvinyl Alcohol ◽  
Carboxymethyl Cellulose ◽  
Food Packaging ◽  
Composite Films ◽  
Nanocomposite Films ◽  
Soil Burial ◽  
High Antibacterial Activity ◽  
Active Food Packaging ◽  
Surface Modified ◽  
Cuo Nanorods

Abstract Herein, we described novel biogenic preparation of the CuO nanorods and its surface modification with L-alanine amino acid accelerated by microwave irradiation. The effect of surface functionalized CuO nanorods on the polyvinyl alcohol/carboxymethyl cellulose film physico-mechanical properties were investigated through various characterization techniques. The tensile strength was improved from 28.58 ± 0.73 MPa to 43.40 ± 0.93 MPa, UV shielding ability and barrier to the water vapors were highly enhanced when PVA/CMC matrices filled with 8 wt% of CuO-L-alanine. In addition, the prepared films exhibited acceptable overall migration limit and readily undergoes soil burial degradation. Nevertheless, CuO-L-alanine incorporated films showed potent antioxidant activity against DPPH radicals and had high antibacterial activity against Staphylococcus aureus and Escherichia coli, and antifungal activity against Candida albicans and Candida tropicalis. Furthermore, the nanocomposite films showed negligible cytotoxic effect on HEK293 and Caco-2 cell lines. In these contexts, the developed nanocomposite films can be implementing as an active food packaging material.

In vitro and in vivo study of carboxymethyl chitosan/polyvinyl alcohol for wound dressing application

2021 ◽  
pp. 51764
Author(s):  
Alireza Akbari ◽  
Shahram Rabbani ◽  
Shiva Irani ◽  
Mojgan Zandi ◽  
Fereshteh Sharifi ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Wound Dressing ◽  
Carboxymethyl Chitosan ◽  
In Vivo Study

Composite Films Based on Polyvinyl Alcohol and Na-Carboxymethyl Cellulose for Separation

2020 ◽  
Vol 93 (7) ◽  
pp. 1003-1008
Author(s):  
G. G. Arakelov ◽  
K. S. Smirnova ◽  
A. G. Nichvolodin ◽  
S. D. Khizhnyak ◽  
A. V. Sokolov ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Carboxymethyl Cellulose ◽  
Composite Films

Synthesis of Glutaraldehyde-Crosslinked Carboxymethyl Cellulose-Polyvinyl Alcohol Film as an Adsorbent for Methylene Blue

2020 ◽  
Vol 840 ◽  
pp. 35-42
Author(s):  
Dwi Siswanta ◽  
Rizky Wahyuni ◽  
Mudasir Mudasir
Keyword(s):  
Methylene Blue ◽  
Polyvinyl Alcohol ◽  
Carboxymethyl Cellulose ◽  
Contact Time ◽  
Order Kinetic ◽  
Casting Technique ◽  
Sem Image ◽  
Ftir Characterization ◽  
Desorption Study ◽  
Polyvinyl Alcohol Film

The glutaraldehyde (GA)-crosslinked carboxymethyl cellulose (CMC)-polyvinyl alcohol (PVA) film had been synthesized and used as a methylene blue adsorbent. The films were prepared using a solution casting technique and characterized using FTIR spectrophotometer, SEM. Adsorption studies include pH, contact time, methylene blue initial concentration. Furthermore, the desorption study of films was carried out using NaCl, HCl and distilled water. The results of FTIR characterization showed similarities between the spectra of CMC-PVA-GA films with their component materials. The SEM image of CMC-PVA-GA films showed a non-porous surface. In the adsorption study, GA-crosslinked CMC-PVA films (1:2 w/w) exhibited the largest adsorption capacity of methylene blue at optimum conditions for adsorption at pH 7, contact time 200 min, methylene blue concentration of 200 mg L–1 which was 194 mg g–1. Methylene blue adsorption kinetic followed the pseudo second-order kinetic model and the Langmuir adsorption isotherm model. The desorption studies show that adsorption takes place through an ion exchange mechanism.

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