scholarly journals The effect of spacing factor on the confinement time of the electrons in a low beta Polywell device

AIP Advances ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 055305
Author(s):  
M. Bagheri ◽  
A. Salar Elahi ◽  
M. K. Salem ◽  
M. Ghoranneviss
Keyword(s):  
Confinement Time ◽  
Spacing Factor

scholarly journals RSF1 in cancer: interactions and functions

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guiyang Cai ◽  
Qing Yang ◽  
Wei Sun
Keyword(s):  
Optimal Level ◽  
Cell Cycle Checkpoint ◽  
Protein Homeostasis ◽  
Clinical Value ◽  
Cancer Proliferation ◽  
Poor Overall Survival ◽  
Cyclin E1 ◽  
Spacing Factor ◽  
Cycle Checkpoint ◽  
Cancer Types

AbstractRSF1, remodelling and spacing factor 1, is an important interphase centromere protein and is overexpressed in many types of cancers and correlated with poor overall survival. RSF1 has functions mainly in maintaining chromosome stability, facilitating DNA repair, maintaining the protein homeostasis of RSF1 and suppressing the transcription of some oncogenes when RSF1 protein is expressed at an optimal level; however, RSF1 overexpression facilitates drug resistance and cell cycle checkpoint inhibition to prompt cancer proliferation and survival. The RSF1 expression level and gene background are crucial for RSF1 functions, which may explain why RSF1 has different functions in different cancer types. This review summarizes the functional domains of RSF1, the overexpression status of RSF1 and SNF2H in cancer based on the TCGA and GTEX databases, the cancer-related functions of RSF1 in interacting with H2Aub, HDAC1, CENP-A, PLK1, ATM, CENP-S, SNF2H, HBX, BubR1, cyclin E1, CBP and NF-κB and the potential clinical value of RSF1, which will lay a theoretical foundation for the structural biology study of RSF1 and application of RSF1 inhibitors, truncated RSF1 proteins and SNF2H inhibitors in the treatment of RSF1-overexpressing tumours.

scholarly journals Maleic Rosin-based Gemini Surfactant as Air Entraining Agent for Concrete under Low Air Pressure

2021 ◽  
Vol 72 (2) ◽  
pp. 27-37
Author(s):  
Yang Li ◽  
Zhendi Wang ◽  
Ling Wang
Keyword(s):  
Dynamic Modulus ◽  
Gemini Surfactant ◽  
Fresh Concrete ◽  
Concrete Strength ◽  
Air Pressure ◽  
Test Results ◽  
Bubble Liquid ◽  
Air Content ◽  
Spacing Factor ◽  
Plateau Area

The effectiveness of Air entraining agent (AEA) in concrete under low air pressure in the plateau area decreased. A type of new AEA, named MRE was synthesized to increase bubbles` stability in fresh concrete under low air pressure. The performance of MRE solution and concrete with MRE were tested under 60 kPa and 100 kPa compared with commercially gemini AEA (DCC). The test results showed that the foam volume of MRE and DCC solution under 60 kPa was reduced by 3% and 9% than under 100 kPa. The bubble liquid film strength of MRE is 63% higher than that of DCC. For concrete with MRE and DCC under 60 kPa, the air content was 2% and 16% lower, the relative dynamic modulus of concrete reduced by 6% and 15%, and the bubble spacing factor under 60 kPa increased by 17% and 39% respectively compared with that under 100 kPa. MRE can increase the freeze-thaw resistance of concrete under low air pressure without affecting concrete strength and is suitable for high altitude concrete.

Reduction of impurity confinement time by combined heating of LHW and ECRH in EAST

2021 ◽  
Author(s):  
Xu Zong ◽  
Wu Zhen-Wei ◽  
Zhang Ling ◽  
Huang Yue-Heng ◽  
Gao Wei ◽  
...  
Keyword(s):  
Confinement Time

Effect of Pumping on Air Characteristics of Conventional Concrete

1996 ◽  
Vol 1532 (1) ◽  
pp. 9-14 ◽  
Author(s):  
M. Lessard ◽  
M. Baalbaki ◽  
P.-C. Aïtcin
Keyword(s):  
Specific Surface ◽  
Freezing And Thawing ◽  
Conventional Concrete ◽  
Freeze Thaw ◽  
Pump Line ◽  
Spacing Factor ◽  
Void System ◽  
The Stability ◽  
Air Void ◽  
Frost Durability

The stability of the air content of concrete during pumping has been the subject of a number of recent investigations. Because increasing volumes of concrete are placed with the aid of pumps and the durability of such concrete to freezing and thawing (ASTM C666) as well as the scaling resistance (ASTM C672) preoccupy engineers, a study concerning the stability of the air-void system of a concrete with 45 to 50 MPa compressive strength was carried out. The slump of the three tested concretes ranged between 85 and 115 mm. Three pumping setups were studied. In the first, the concrete was pumped horizontally; in the second the concrete was pumped upward and then downward. In the third, the vertical setup was used but a reduced section was placed at the end of the pump line, and the concrete was allowed to free fall a short distance. For each pump setup, the concrete was sampled before being placed in the pump and after leaving the pump. The results clearly show that when the concrete is pumped horizontally, the spacing factor (L) and the specific surface of the air-void system are barely altered. On the other hand, after pumping the concrete vertically without a reduced end section, it was impossible to obtain an L less than 230 μm, the maximum spacing factor allowed by Canadian standards (CSA A23.1) to ensure good frost durability. Furthermore, the specific surface of the air bubbles fell to 20 mm−1, which is inferior to the 25-mm−1 value recommended in Canadian standards. By placing a reduced section at the end of the vertical pump line, it was possible to enhance the air-void system but that procedure still fell short of ensuring a system that satisfies the air-void system recommended by Canadian standards to ensure proper frost durability. Although the pumped concrete mixtures did not always satisfy the requirements of CSA A23.1 regarding air-void systems, they satisfied the requirements of ASTM C666 (Procedure A) for resistance to freeze-thaw cycles. Freeze-thaw resistance in the presence of deicing salts was evaluated according to ASTM C672. After 50 frost cycles, all but one concrete exhibited mass losses that were lower than the maximum permissible limit of 0.50 kg/m2 required by BNQ 2621-900, the standard currently enforced in the province of Quebec. Placing a reduced section at the end of the pump line creates a light counterpressure in the descending section of the pump line, which allows the conservation of an acceptable air-void system. Considering the appreciable improvement in the preservation of air-void characteristics when a reduced section was placed at the end of the pump line, it was decided to proceed with further experimental work using four 90-degree elbows placed at the end of the vertically hanging pump line.

Sign in / Sign up

Export Citation Format

Share Document