Elucidation of isoflurane action mechanism on surgical diabetes using microfluidic device

Tribological Performance and Action Mechanism of Cadmium Dialkyldithiophosphate

Tribology Transactions ◽

10.1080/05698190590923888 ◽

2005 ◽

Vol 48 (2) ◽

pp. 171-175 ◽

Cited By ~ 5

Author(s):

Hu Jianqiang ◽

Wei Xianyong ◽

Yao Junbing ◽

Xie Feng ◽

Zhu Huanqin ◽

...

Keyword(s):

Tribological Performance ◽

Action Mechanism

Download Full-text

The Action Mechanism of the Purified Platelet Aggregation Principle of Trimeresurus mucrosquamatus Venom

Thrombosis and Haemostasis ◽

10.1055/s-0038-1646800 ◽

1979 ◽

Vol 41 (03) ◽

pp. 475-490 ◽

Cited By ~ 20

Author(s):

Chaoho Ouyang ◽

Che-Ming Teng

Keyword(s):

Platelet Aggregation ◽

Adenine Nucleotides ◽

Muscle Relaxants ◽

Prostaglandin Synthesis ◽

Action Mechanism ◽

Crude Venom ◽

Platelet Factor ◽

Induce Platelet Aggregation ◽

Minimal Concentration ◽

Aggregation Principle

SummaryThe minimal concentration of the platelet aggregation principle (Platelet Aggregoserpen- tin, PAS) necessary to induce platelet aggregation was 10 ng/ml, about one-hundredth of that of the crude venom. PAS induced the release of platelet factors 3 and 4 from platelets, but the released platelet factor 3 was easily inactivated by the anti-phospholipid effect of PAS. Pretreatment of platelets with neuraminidase potentiated PAS-induced platelet aggregation. PAS-induced platelet aggregation was independent on released ADP; it could occur in the ADP-removing systems, such as apyrase or a combination of phosphoenolpyruvate and pyruvate kinase. However, PAS-induced platelet aggregation could be inhibited by adenine nucleotides and adenosine.PAS-induced platelet aggregation was inhibited by some anti-inflammatory agents, antimalarial drugs, local anesthetics, antihistamine and smooth muscle relaxants. After deaggregation of PAS-treated platelets, thrombin and sodium arachidonate could further induce platelet aggregation, but ADP and second dose of PAS could not. It is concluded that PAS-induced platelet aggregation is due to prostaglandin synthesis. Recent literatures on the mechanism of platelet aggregation were surveyed and the actions of PAS were discussed.

Download Full-text

Alkylation of carboxylic acids in a microfluidic device: kinetics parameters determination, Hammett reaction constant measurement and optimization of preparative experiment

10.3390/ecsoc-13-00198 ◽

2009 ◽

Cited By ~ 1

Author(s):

Christian Rolando ◽

Maël Penhoat ◽

Azarmidokht Gholamipour-Shirazi

Keyword(s):

Carboxylic Acids ◽

Microfluidic Device ◽

Kinetics Parameters ◽

Constant Measurement ◽

Reaction Constant

Download Full-text

Novel Microfluidic Device Integrated with a Fluidic-Capacitor to Mimic Heart Beating for Generation of Functional Liver Organoids

IEEJ Transactions on Sensors and Micromachines ◽

10.1541/ieejsmas.139.209 ◽

2019 ◽

Vol 139 (7) ◽

pp. 209-216

Author(s):

Jiaxu Wu ◽

Yoshikazu Hirai ◽

Ken-ichiro Kamei ◽

Toshiyuki Tsuchiya ◽

Osamu Tabata

Keyword(s):

Microfluidic Device ◽

Heart Beating ◽

Liver Organoids

Download Full-text

Pneumatically-driven Microfluidic Device for Evaluating Active Transport by Kinesin Motor Protein

IEEJ Transactions on Sensors and Micromachines ◽

10.1541/ieejsmas.136.384 ◽

2016 ◽

Vol 136 (9) ◽

pp. 384-389

Author(s):

Kazuya Fujimoto ◽

Hirofumi Shintaku ◽

Hidetoshi Kotera ◽

Ryuji Yokokawa

Keyword(s):

Active Transport ◽

Microfluidic Device ◽

Motor Protein ◽

Kinesin Motor

Download Full-text

A microfluidic device with integrated impedance detection for λ-DNA

MRS Proceedings ◽

10.1557/proc-773-n6.5 ◽

2003 ◽

Vol 773 ◽

Cited By ~ 1

Author(s):

Myung-Il Park ◽

Jonging Hong ◽

Dae Sung Yoon ◽

Chong-Ook Park ◽

Geunbae Im

Keyword(s):

Microfluidic Device ◽

Electrochemical Impedance ◽

Direct Detection ◽

Full Potential ◽

Label Free ◽

Buffer Solution ◽

Detection Systems ◽

Significant Difference ◽

Detection Of Biomolecules ◽

Impedance Magnitude

AbstractThe large optical detection systems that are typically utilized at present may not be able to reach their full potential as portable analysis tools. Accurate, early, and fast diagnosis for many diseases requires the direct detection of biomolecules such as DNA, proteins, and cells. In this research, a glass microchip with integrated microelectrodes has been fabricated, and the performance of electrochemical impedance detection was investigated for the biomolecules. We have used label-free λ-DNA as a sample biomolecule. By changing the distance between microelectrodes, the significant difference between DW and the TE buffer solution is obtained from the impedance-frequency measurements. In addition, the comparison for the impedance magnitude of DW, the TE buffer, and λ-DNA at the same distance was analyzed.

Download Full-text