scholarly journals Perspective: Aligned arrays of electrospun nanofibers for directing cell migration

APL Materials ◽  
2018 ◽  
Vol 6 (12) ◽  
pp. 120902 ◽  
Author(s):  
Jiajia Xue ◽  
Tong Wu ◽  
Younan Xia
Keyword(s):  
Cell Migration ◽  
Electrospun Nanofibers ◽  
Aligned Arrays

Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-ε-caprolactone and a collagen/poly-ε-caprolactone blend

Biomaterials ◽  
2007 ◽  
Vol 28 (19) ◽  
pp. 3012-3025 ◽  
Author(s):  
Eva Schnell ◽  
Kristina Klinkhammer ◽  
Simone Balzer ◽  
Gary Brook ◽  
Doris Klee ◽  
...  
Keyword(s):  
Cell Migration ◽  
Glial Cell ◽  
Electrospun Nanofibers ◽  
Axonal Growth

Abstract 1433: Analysis of tumor cell migration on electrospun nanofibers identifies STAT3 as a pro-migratory target in gliomas

2011 ◽  
Author(s):  
Jessica De Jesus ◽  
Paula A. Agudelo ◽  
Shante Williams ◽  
Michal O. Nowicki ◽  
Pui K. Li ◽  
...  
Keyword(s):  
Cell Migration ◽  
Tumor Cell ◽  
Electrospun Nanofibers ◽  
Tumor Cell Migration

Neutrophil migration through in vitro interstitial matrix

1992 ◽  
Vol 50 (1) ◽  
pp. 894-895
Author(s):  
J. Roemer ◽  
S.R. Simon
Keyword(s):  
Extracellular Matrix ◽  
Smooth Muscle ◽  
Cell Migration ◽  
Smooth Muscle Cells ◽  
Inflammatory Cell ◽  
Neutrophil Migration ◽  
Culture Conditions ◽  
Aortic Smooth Muscle ◽  
Specific Culture

We are developing an in vitro interstitial extracellular matrix (ECM) system for study of inflammatory cell migration. Falcon brand Cyclopore membrane inserts of various pore sizes are used as a support substrate for production of ECM by R22 rat aortic smooth muscle cells. Under specific culture conditions these cells produce a highly insoluble matrix consisting of typical interstitial ECM components, i.e.: types I and III collagen, elastin, proteoglycans and fibronectin.

The role of DUBs in the post-translational control of cell migration

2019 ◽  
Vol 63 (5) ◽  
pp. 579-594 ◽  
Author(s):  
Guillem Lambies ◽  
Antonio García de Herreros ◽  
Víctor M. Díaz
Keyword(s):  
Cell Migration ◽  
Translational Control ◽  
Epithelial To Mesenchymal Transition ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling ◽  
Mesenchymal Transition ◽  
Tgfβ Receptors ◽  
Fundamental Process ◽  
Multistep Process

Abstract Cell migration is a multifactorial/multistep process that requires the concerted action of growth and transcriptional factors, motor proteins, extracellular matrix remodeling and proteases. In this review, we focus on the role of transcription factors modulating Epithelial-to-Mesenchymal Transition (EMT-TFs), a fundamental process supporting both physiological and pathological cell migration. These EMT-TFs (Snail1/2, Twist1/2 and Zeb1/2) are labile proteins which should be stabilized to initiate EMT and provide full migratory and invasive properties. We present here a family of enzymes, the deubiquitinases (DUBs) which have a crucial role in counteracting polyubiquitination and proteasomal degradation of EMT-TFs after their induction by TGFβ, inflammatory cytokines and hypoxia. We also describe the DUBs promoting the stabilization of Smads, TGFβ receptors and other key proteins involved in transduction pathways controlling EMT.

Monitoring stem cell migration in the nervous system by in vivo magnetic resonance imaging

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S692-S692
Author(s):  
Mathias Hoehn ◽  
Uwe Himmelreich ◽  
Ralph Weber ◽  
Pedro Ramos-Cabrer ◽  
Susanne Wegener ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Nervous System ◽  
Stem Cell ◽  
Cell Migration ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Stem Cell Migration
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