scholarly journals Invited Article: Label-free nerve imaging with a coherent anti-Stokes Raman scattering rigid endoscope using two optical fibers for laser delivery

APL Photonics ◽  
2018 ◽  
Vol 3 (9) ◽  
pp. 092407 ◽  
Author(s):  
Keigo Hirose ◽  
Shuichiro Fukushima ◽  
Taichi Furukawa ◽  
Hirohiko Niioka ◽  
Mamoru Hashimoto
Keyword(s):  
Raman Scattering ◽  
Optical Fibers ◽  
Label Free ◽  
Rigid Endoscope ◽  
Nerve Imaging ◽  
Anti Stokes

scholarly journals Author Correction: Improvement of nerve imaging speed with coherent anti-Stokes Raman scattering rigid endoscope using deep-learning noise reduction

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Naoki Yamato ◽  
Hirohiko Niioka ◽  
Jun Miyake ◽  
Mamoru Hashimoto
Keyword(s):  
Deep Learning ◽  
Raman Scattering ◽  
Noise Reduction ◽  
Rigid Endoscope ◽  
Nerve Imaging ◽  
Anti Stokes ◽  
Imaging Speed

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Improvement of nerve imaging speed with coherent anti-Stokes Raman scattering rigid endoscope using deep-learning noise reduction

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Naoki Yamato ◽  
Hirohiko Niioka ◽  
Jun Miyake ◽  
Mamoru Hashimoto
Keyword(s):  
Deep Learning ◽  
Raman Scattering ◽  
Noise Reduction ◽  
Fine Tuning ◽  
Nerve Sparing ◽  
Learning Models ◽  
Rigid Endoscope ◽  
Nerve Imaging ◽  
Anti Stokes ◽  
Imaging Speed

Abstract A coherent anti-Stokes Raman scattering (CARS) rigid endoscope was developed to visualize peripheral nerves without labeling for nerve-sparing endoscopic surgery. The developed CARS endoscope had a problem with low imaging speed, i.e. low imaging rate. In this study, we demonstrate that noise reduction with deep learning boosts the nerve imaging speed with CARS endoscopy. We employ fine-tuning and ensemble learning and compare deep learning models with three different architectures. In the fine-tuning strategy, deep learning models are pre-trained with CARS microscopy nerve images and retrained with CARS endoscopy nerve images to compensate for the small dataset of CARS endoscopy images. We propose using the equivalent imaging rate (EIR) as a new evaluation metric for quantitatively and directly assessing the imaging rate improvement by deep learning models. The highest EIR of the deep learning model was 7.0 images/min, which was 5 times higher than that of the raw endoscopic image of 1.4 images/min. We believe that the improvement of the nerve imaging speed will open up the possibility of reducing postoperative dysfunction by intraoperative nerve identification.

scholarly journals Coherent anti-Stokes Raman scattering rigid endoscope toward robot-assisted surgery

2018 ◽  
Vol 9 (2) ◽  
pp. 387 ◽  
Author(s):  
K. Hirose ◽  
T. Aoki ◽  
T. Furukawa ◽  
S. Fukushima ◽  
H. Niioka ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Robot Assisted ◽  
Rigid Endoscope ◽  
Anti Stokes ◽  
Robot Assisted Surgery

Label-Free Imaging of Adipogenesis by Coherent Anti-Stokes Raman Scattering Microscopy

2014 ◽  
pp. 189-201 ◽  
Author(s):  
Antti Isomäki ◽  
Tarvo Sillat ◽  
Mari Ainola ◽  
Mikko Liljeström ◽  
Yrjö T. Konttinen ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Label Free ◽  
Anti Stokes

scholarly journals Coherent anti-Stokes Raman scattering for label-free biomedical imaging

2013 ◽  
Vol 15 (9) ◽  
pp. 094006 ◽  
Author(s):  
Imran I Patel ◽  
Christian Steuwe ◽  
Stefanie Reichelt ◽  
Sumeet Mahajan
Keyword(s):  
Raman Scattering ◽  
Biomedical Imaging ◽  
Label Free ◽  
Anti Stokes

Label-Free Imaging of Lipophilic Bioactive Molecules during Lipid Digestion by Multiplex Coherent Anti-Stokes Raman Scattering Microspectroscopy

2010 ◽  
Vol 132 (24) ◽  
pp. 8433-8439 ◽  
Author(s):  
James P. R. Day ◽  
Gianluca Rago ◽  
Katrin F. Domke ◽  
Krassimir P. Velikov ◽  
Mischa Bonn
Keyword(s):  
Raman Scattering ◽  
Bioactive Molecules ◽  
Label Free ◽  
Lipid Digestion ◽  
Anti Stokes

Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS) for the analysis of biological specimens

2011 ◽  
Vol 36 (12) ◽  
pp. 2309 ◽  
Author(s):  
Charles H. Camp, Jr. ◽  
Siva Yegnanarayanan ◽  
Ali A. Eftekhar ◽  
Ali Adibi
Keyword(s):  
Flow Cytometry ◽  
Raman Scattering ◽  
Free Flow ◽  
Label Free ◽  
Anti Stokes

scholarly journals Label-Free Fluctuation Spectroscopy Based on Coherent Anti-Stokes Raman Scattering from Bulk Water Molecules

ChemPhysChem ◽  
2016 ◽  
Vol 17 (7) ◽  
pp. 1025-1033 ◽  
Author(s):  
M. D. Rabasovic ◽  
E. Sisamakis ◽  
S. Wennmalm ◽  
J. Widengren
Keyword(s):  
Raman Scattering ◽  
Bulk Water ◽  
Water Molecules ◽  
Label Free ◽  
Anti Stokes

scholarly journals Label-Free Delineation of Brain Tumors by Coherent Anti-Stokes Raman Scattering Microscopy in an Orthotopic Mouse Model and Human Glioblastoma

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e107115 ◽  
Author(s):  
Ortrud Uckermann ◽  
Roberta Galli ◽  
Sandra Tamosaityte ◽  
Elke Leipnitz ◽  
Kathrin D. Geiger ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Mouse Model ◽  
Raman Scattering ◽  
Label Free ◽  
Orthotopic Mouse Model ◽  
Human Glioblastoma ◽  
Anti Stokes
Sign in / Sign up

Export Citation Format

Share Document