Automated processing of first-pass radioisotope ventriculography data to determine essential central circulation parameters

2017 ◽  
Author(s):  
Aleksei Krotov ◽  
Victor Pankin
Keyword(s):  
First Pass ◽  
Circulation Parameters ◽  
Automated Processing ◽  
Central Circulation

scholarly journals Combined inhalational and intravenous anesthesia at surgeries in patients with gastrointestinal cancers

2012 ◽  
Vol 93 (5) ◽  
pp. 728-731
Author(s):  
M I Neimark ◽  
S Z Tanatarov ◽  
T A Adylkhanov
Keyword(s):  
Serum Cortisol ◽  
Gastrointestinal Cancers ◽  
Inhalational Anesthesia ◽  
Intravenous Anesthesia ◽  
Glucose Levels ◽  
Significant Difference ◽  
Circulation Parameters ◽  
Head Of The Pancreas ◽  
Combined Anesthesia ◽  
Central Circulation

Aim. To define efficiency and safety of the combined inhalational and intravenous anesthesia (isoflurane + propofol) in patients operated due to gastrointestinal cancer. Methods. 163 patients who were operated due to gastric cancer (119 patients), cancer of the head of the pancreas (24 patients) and colon cancer (20 patients) were examined. Central circulation parameters, autonomic nervous system status, serum cortisol and glucose levels, bispectral index in patients who underwent inhalational or combined inhalational and intravenous anesthesia were compared. Results. There was no significant difference of the examined parameters in patients who underwent combined inhalational and intravenous anesthesia (isoflurane + propofol) compared to patients in whom only inhalational anesthesia with isoflurane was used. Combination was characterized by less change of the examined parameters compared to baseline levels and prolonged emergence from anesthesia. Conclusion. Combined anesthesia is quite safe and effective if used in oncosurgery.

scholarly journals A simple method for detecting chaos in nature

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Daniel Toker ◽  
Friedrich T. Sommer ◽  
Mark D’Esposito
Keyword(s):  
Common Edge ◽  
Simple Method ◽  
Small Perturbations ◽  
Functional Roles ◽  
Processing Pipeline ◽  
Chaos Detection ◽  
Highly Sensitive ◽  
First Pass ◽  
Automated Processing ◽  
Health And Disease

AbstractChaos, or exponential sensitivity to small perturbations, appears everywhere in nature. Moreover, chaos is predicted to play diverse functional roles in living systems. A method for detecting chaos from empirical measurements should therefore be a key component of the biologist’s toolkit. But, classic chaos-detection tools are highly sensitive to measurement noise and break down for common edge cases, making it difficult to detect chaos in domains, like biology, where measurements are noisy. However, newer tools promise to overcome these limitations. Here, we combine several such tools into an automated processing pipeline, and show that our pipeline can detect the presence (or absence) of chaos in noisy recordings, even for difficult edge cases. As a first-pass application of our pipeline, we show that heart rate variability is not chaotic as some have proposed, and instead reflects a stochastic process in both health and disease. Our tool is easy-to-use and freely available.

Automated processing of first-pass radionuclide angiocardiography by factor analysis of dynamic structures

1987 ◽  
Vol 8 (5) ◽  
pp. 375-388 ◽  
Author(s):  
F. CAVAILLOLES ◽  
J. -P. BAZIN ◽  
A. CAPDEROU ◽  
H. VALETTE ◽  
J. -L. HEBERT ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Radionuclide Angiocardiography ◽  
First Pass ◽  
Automated Processing ◽  
Dynamic Structures

Embedding Procedure for Water Swollen Samples

1970 ◽  
Vol 28 ◽  
pp. 504-505
Author(s):  
Ann M. Thomas ◽  
Virginia Shemeley
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Ion Exchange ◽  
Structural Changes ◽  
Cross Linking ◽  
Ion Exchange Resins ◽  
Transmission Electron ◽  
First Pass ◽  
Exchange Resins

Those samples which swell rapidly when exposed to water are, at best, difficult to section for transmission electron microscopy. Some materials literally burst out of the embedding block with the first pass by the knife, and even the most rapid cutting cycle produces sections of limited value. Many ion exchange resins swell in water; some undergo irreversible structural changes when dried. We developed our embedding procedure to handle this type of sample, but it should be applicable to many materials that present similar sectioning difficulties.The purpose of our embedding procedure is to build up a cross-linking network throughout the sample, while it is in a water swollen state. Our procedure was suggested to us by the work of Rosenberg, where he mentioned the formation of a tridimensional structure by the polymerization of the GMA biproduct, triglycol dimethacrylate.

Convergent-beam thickness determination: The advantages of digital imaging

1994 ◽  
Vol 52 ◽  
pp. 420-421
Author(s):  
Stuart McKernan ◽  
C. Barry Carter
Keyword(s):  
Intensity Variation ◽  
Convergent Beam Electron Diffraction ◽  
Digital Data ◽  
Thickness Determination ◽  
Frequent Use ◽  
Automated Processing ◽  
Beam Thickness ◽  
Convergent Beam ◽  
Remarkable Agreement

Convergent-beam electron diffraction (CBED) patterns contain an immense amount of information relating to the structure of the material from which they are obtained. The analysis of these patterns has progressed to the point that under appropriate, well specified conditions, the intensity variation within the CBED discs may be understood in a quantitative sense. Rossouw et al for example, have produced numerical simulations of zone-axis CBED patterns which show remarkable agreement with experimental patterns. Spence and co-workers have obtained the structure factor parameters for lowindex reflections using the intensity variation in 2-beam CBED patterns. Both of these examples involve the use of digital data. Perhaps the most frequent use for quantitative CBED analysis is the thickness determination described by Kelly et al. This analysis has been implemented in a variety of different ways; from real-time, in-situ analysis using the microscope controls, to measurements of photographic prints with a ruler, to automated processing of digitally acquired images. The potential advantages of this latter process will be presented.

Evidence for Early closure Attachment on First pass Reading Times in French

1997 ◽  
Vol 50 (2) ◽  
pp. 421-438 ◽  
Author(s):  
Daniel Zagar ◽  
Joel Pynte ◽  
Sylvie Rativeau
Keyword(s):  
First Pass ◽  
Early Closure

Therapie mit Opioiden bei Patienten mit Leberzirrhose

2020 ◽  
Vol 77 (1) ◽  
pp. 14-19
Author(s):  
Stephan Krähenbühl
Keyword(s):  
First Pass

Zusammenfassung. Für die Dosisangleichung bei Patienten mit Leberzirrhose gibt es keinen verlässlichen endogenen Parameter, der die metabolische Aktivität und das Ausmass der portacavalen Shunts repräsentiert. Die Angleichung muss deshalb unter Beachtung der pharmakokinetischen Eigenschaften der verabreichten Arzneistoffe erfolgen. Bei Arzneistoffen mit einem starken Abbau während der ersten Passage durch die Leber (first-pass Effekt) muss nach oraler Verabreichung mit einer Zunahme der Bioverfügbarkeit und verminderter Clearance gerechnet werden. Nach topischer, buccaler oder parenteraler Applikation spielt nur der Effekt auf die Clearance eine Rolle. Für Arzneistoffe mit einer hohen Bioverfügbarkeit (> 70 %) ist ebenfalls nur die hepatische Clearance entscheidend. In der Folge werden die in der Schweiz gebräuchlichen Opioide bezüglich pharmakokinetischer Eigenschaften und Konsequenzen bezüglich Dosisangleichung bei Patienten mit Leberzirrhose besprochen. Buprenorphin, Fentanyl, Hydromorphon, Morphin, Naloxon und Tapentadol sind Arzneistoffe mit einem hohen first-pass Effekt, währenddem Methadon, Oxycodon und Tramadol eine Bioverfügbarkeit von > 70 % aufweisen.

Einfluss der Gadofosveset-Injektionsgeschwindigkeit auf die Bildqualität der First-Pass MRA

2009 ◽  
Vol 181 (S 01) ◽  
Author(s):  
HJ Michaely ◽  
UI Attenberger ◽  
C Fink ◽  
O Dietrich ◽  
SO Schoenberg
Keyword(s):  
First Pass

Demonstration and Quantitation of Pharmacological Inhibition of Pulmonary Uptake of N-lsopropyl-123l-p-lodoamphetamine by Propranolol

1989 ◽  
Vol 28 (03) ◽  
pp. 100-104 ◽  
Author(s):  
S. F. Akber
Keyword(s):  
Binding Sites ◽  
Bolus Injection ◽  
Cell Function ◽  
Lung Pathology ◽  
Lung Uptake ◽  
Pharmacological Inhibition ◽  
Sensitive Index ◽  
Pulmonary Uptake ◽  
First Pass

The first-pass pulmonary extraction values of N-lsopropyl-123l-p-lodoamphetamine (123I-IMP) in pretreated dogs decreases from 90 to 62% as the amount of propranolol increases from 0 to 20 mg. The first-pass pulmonary extraction values of 123I-IMP in dogs with a simultaneous bolus injection of propranolol decreases from 90 to 62% as the amount of propranolol increases from 0 to 10 mg. The pulmonary extraction of 123I-IMP with a simultaneous bolus injection of ketamine and 123I-IMP decreases from 90 to 64% as the ketamine dose increases from 0 to 100 mg. These results suggest that the pulmonary uptake of 123I-IMP may be at least partially mediated by receptors. They also indicate that endothelial metabolic cell function may be a useful index of early lung pathology. Furthermore, studies of the degree of lung uptake may be a sensitive index of pathologic states in which alterations of amine binding sites have occurred.

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