Separating medial olivocochlear from acoustic reflex effects on transient evoked otoacoustic emissions in unanesthetized mice

2015 ◽  
Author(s):  
Yingyue Xu ◽  
Mary Ann Cheatham ◽  
Jonathan Siegel
Keyword(s):  
Otoacoustic Emissions ◽  
Acoustic Reflex ◽  
Transient Evoked Otoacoustic Emissions ◽  
Medial Olivocochlear

scholarly journals Frequency tuning of medial-olivocochlear-efferent acoustic reflexes in humans as functions of probe frequency

2012 ◽  
Vol 107 (6) ◽  
pp. 1598-1611 ◽  
Author(s):  
Watjana Lilaonitkul ◽  
John J. Guinan
Keyword(s):  
Otoacoustic Emissions ◽  
Frequency Tuning ◽  
Stimulus Frequency ◽  
Phase Changes ◽  
Acoustic Reflex ◽  
Wide Range ◽  
Acoustic Reflexes ◽  
Specific Feedback ◽  
Stimulus Frequency Otoacoustic Emissions ◽  
Medial Olivocochlear

The medial-olivocochlear (MOC) acoustic reflex is thought to provide frequency-specific feedback that adjusts the gain of cochlear amplification, but little is known about how frequency specific the reflex actually is. We measured human MOC tuning through changes in stimulus frequency otoacoustic emissions (SFOAEs) from 40-dB-SPL tones at probe frequencies ( fps) near 0.5, 1.0, and 4.0 kHz. MOC activity was elicited by 60-dB-SPL ipsilateral, contralateral, or bilateral tones or half-octave noise bands, with elicitor frequency ( fe) varied in half-octave steps. Tone and noise elicitors produced similar results. At all probe frequencies, SFOAE changes were produced by a wide range of elicitor frequencies with elicitor frequencies near 0.7–2.0 kHz being particularly effective. MOC-induced changes in SFOAE magnitude and SFOAE phase were surprisingly different functions of fe: magnitude inhibition largest for fe close to fp, phase change largest for fe remote from fp. The metric ΔSFOAE, which combines both magnitude and phase changes, provided the best match to reported (cat) MOC neural inhibition. Ipsilateral and contralateral MOC reflexes often showed dramatic differences in plots of MOC effect vs. elicitor frequency, indicating that the contralateral reflex does not give an accurate picture of ipsilateral-reflex properties. These differences in MOC effects appear to imply that ipsilateral and contralateral reflexes have different actions in the cochlea. The implication of these results for MOC function, cochlear mechanics, and the production of SFOAEs are discussed.

Acceptable Noise Level, Phoneme Recognition in Noise, and Measures of Auditory Efferent Activity

2005 ◽  
Vol 16 (08) ◽  
pp. 530-545 ◽  
Author(s):  
Ashley W. Harkrider ◽  
Steven Brad Smith
Keyword(s):  
Individual Differences ◽  
Noise Level ◽  
Otoacoustic Emissions ◽  
Intersubject Variability ◽  
Acoustic Reflex ◽  
Phoneme Recognition ◽  
Efferent Activity ◽  
Acceptable Noise Level ◽  
Auditory Efferent ◽  
Medial Olivocochlear

Acceptable noise level (ANL) is unrelated to sentence recognition in noise but may be related to phoneme recognition in noise (PRN). Individual differences in efferent activity in medial olivocochlear bundle (MOCB) and acoustic reflex (AR) pathways may account for intersubject variability in ANL and PRN. Monotic and dichotic ANL, monotic PRN, contralateral suppression of transient evoked otoacoustic emissions, and ipsilateral and contralateral acoustic reflex thresholds were measured in 31 adults with normal hearing. Results indicate that monotic ANL and PRN are unrelated. Monotic and dichotic ANL are related, suggesting that nonperipheral factors mediate ANL. Intersubject variability in ANL cannot be accounted for by individual differences in MOCB or AR activation. Intersubject variability in PRN cannot be accounted for by individual differences in MOCB or contralateral AR activation. It may be influenced by the ipsilateral AR pathway. Efferent activity in the contralateral AR arc is correlated with efferent activity in the MOCB.

Does Hyperandrogenism Affect the Otoacoustic Emissions and Medial Olivocochlear Reflex in Female Adults?

2013 ◽  
Vol 34 (5) ◽  
pp. 784-789 ◽  
Author(s):  
Erdem Eren ◽  
Ece Harman ◽  
Seçil Arslanoğlu ◽  
Kazm Önal ◽  
Hüseyin Katlmiş
Keyword(s):  
Otoacoustic Emissions ◽  
Medial Olivocochlear Reflex ◽  
Medial Olivocochlear

scholarly journals Comparisons of transient evoked otoacoustic emissions using chirp and click stimuli

2016 ◽  
Vol 140 (3) ◽  
pp. 1949-1973 ◽  
Author(s):  
Douglas H. Keefe ◽  
M. Patrick Feeney ◽  
Lisa L. Hunter ◽  
Denis F. Fitzpatrick
Keyword(s):  
Otoacoustic Emissions ◽  
Transient Evoked Otoacoustic Emissions
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