High-speed adaptive contact-mode atomic force microscopy imaging with near-minimum-force

2014 ◽  
Vol 85 (7) ◽  
pp. 073706 ◽  
Author(s):  
Juan Ren ◽  
Qingze Zou
Keyword(s):  
Atomic Force Microscopy ◽  
High Speed ◽  
Contact Mode ◽  
Microscopy Imaging ◽  
Force Microscopy ◽  
Atomic Force ◽  
Atomic Force Microscopy Imaging ◽  
Minimum Force ◽  
Mode Atomic Force Microscopy

scholarly journals High-speed dynamic-mode atomic force microscopy imaging of polymers: an adaptive multiloop-mode approach

2017 ◽  
Vol 8 ◽  
pp. 1563-1570 ◽  
Author(s):  
Juan Ren ◽  
Qingze Zou
Keyword(s):  
Atomic Force Microscopy ◽  
High Speed ◽  
Interaction Force ◽  
Dynamic Mode ◽  
Microscopy Imaging ◽  
Force Microscopy ◽  
Atomic Force ◽  
Atomic Force Microscopy Imaging ◽  
Mode Tm ◽  
Mode Atomic Force Microscopy

Adaptive multiloop-mode (AMLM) imaging to substantially increase (over an order of magnitude) the speed of tapping-mode (TM) imaging is tested and evaluated through imaging three largely different heterogeneous polymer samples in experiments. It has been demonstrated that AMLM imaging, through the combination of a suite of advanced control techniques, is promising to achieve high-speed dynamic-mode atomic force microscopy imaging. The performance, usability, and robustness of the AMLM in various imaging applications, however, is yet to be assessed. In this work, three benchmark polymer samples, including a PS–LDPE sample, an SBS sample, and a Celgard sample, differing in feature size and stiffness of two orders of magnitude, are imaged using the AMLM technique at high-speeds of 25 Hz and 20 Hz, respectively. The comparison of the images obtained to those obtained by using TM imaging at scan rates of 1 Hz and 2 Hz showed that the quality of the 25 Hz and 20 Hz AMLM imaging is at the same level of that of the 1 Hz TM imaging, while the tip–sample interaction force is substantially smaller than that of the 2 Hz TM imaging.

Contact mode atomic force microscopy imaging of nanometer‐sized particles

1995 ◽  
Vol 66 (24) ◽  
pp. 3295-3297 ◽  
Author(s):  
T. Junno ◽  
S. Anand ◽  
K. Deppert ◽  
L. Montelius ◽  
L. Samuelson
Keyword(s):  
Atomic Force Microscopy ◽  
Contact Mode ◽  
Microscopy Imaging ◽  
Force Microscopy ◽  
Atomic Force ◽  
Atomic Force Microscopy Imaging ◽  
Mode Atomic Force Microscopy

High-speed atomic force microscopy: Imaging and force spectroscopy

FEBS Letters ◽  
2014 ◽  
Vol 588 (19) ◽  
pp. 3631-3638 ◽  
Author(s):  
Frédéric Eghiaian ◽  
Felix Rico ◽  
Adai Colom ◽  
Ignacio Casuso ◽  
Simon Scheuring
Keyword(s):  
Atomic Force Microscopy ◽  
High Speed ◽  
Force Spectroscopy ◽  
Microscopy Imaging ◽  
Force Microscopy ◽  
Atomic Force ◽  
Atomic Force Microscopy Imaging

scholarly journals Structural Evidence for α-Synuclein Fibrils Using in Situ Atomic Force Microscopy

2005 ◽  
Vol 37 (2) ◽  
pp. 113-118
Author(s):  
Feng Zhang ◽  
Li-Na Ji ◽  
Lin Tang ◽  
Jun Hu ◽  
Hong-Yu Hu ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Guanidine Hydrochloride ◽  
Indirect Evidence ◽  
Contact Mode ◽  
Microscopy Imaging ◽  
Tapping Mode ◽  
Force Microscopy ◽  
Atomic Force ◽  
Mode Atomic Force Microscopy

Abstract Human α-synuclein is a presynaptic terminal protein and can form insoluble fibrils that are believed to play an important role in the pathogenesis of several neurodegenerative diseases such as Parkinson's disease, dementia with Lewy bodies and Lewy body variant of Alzheimer's disease. In this paper, in situ atomic force microscopy has been used to study the structural properties of α-synuclein fibrils in solution using two different atomic force microscopy imaging modes: tapping mode and contact mode. In the in situ contact mode atomic force microscopy experiments α-synuclein fibrils quickly broke into fragments, and a similar phenomenon was found using tapping mode atomic force microscopy in which α-synuclein fibrils were incubated with guanidine hydrochloride (0.6 M). The α-synuclein fibrils kept their original filamentous topography for over 1 h in the in situ tapping mode atomic force microscopy experiments. The present results provide indirect evidence on how β-sheets assemble into α-synuclein fibrils on a nanometer scale.

Improving the signal-to-noise ratio of high-speed contact mode atomic force microscopy

2012 ◽  
Vol 83 (8) ◽  
pp. 083710 ◽  
Author(s):  
O. D. Payton ◽  
L. Picco ◽  
M. J. Miles ◽  
M. E. Homer ◽  
A. R. Champneys
Keyword(s):  
Atomic Force Microscopy ◽  
High Speed ◽  
Signal To Noise Ratio ◽  
Signal To Noise ◽  
Contact Mode ◽  
Force Microscopy ◽  
Atomic Force ◽  
Noise Ratio ◽  
Mode Atomic Force Microscopy

scholarly journals High-speed atomic force microscopy imaging of live mammalian cells

2017 ◽  
Vol 14 (0) ◽  
pp. 127-135 ◽  
Author(s):  
Mikihiro Shibata ◽  
Hiroki Watanabe ◽  
Takayuki Uchihashi ◽  
Toshio Ando ◽  
Ryohei Yasuda
Keyword(s):  
Atomic Force Microscopy ◽  
Mammalian Cells ◽  
High Speed ◽  
Microscopy Imaging ◽  
Force Microscopy ◽  
Atomic Force ◽  
Atomic Force Microscopy Imaging
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