General anesthesia suppresses normal heart rate variability in humans

2014 ◽  
Vol 24 (2) ◽  
pp. 023129 ◽  
Author(s):  
Gerald Matchett ◽  
Philip Wood
2014 ◽  
Vol 24 (2) ◽  
pp. 206-214 ◽  
Author(s):  
Wisse P. van der Meijden ◽  
Rolf Fronczek ◽  
Robert H. A. M. Reijntjes ◽  
Eleonora P. M. Corssmit ◽  
Nienke R. Biermasz ◽  
...  

2013 ◽  
Vol 14 ◽  
pp. e205
Author(s):  
W. Van Der Meijden ◽  
R. Fronczek ◽  
R. Reijntjes ◽  
G. Lammers ◽  
G. Van Dijk ◽  
...  

2017 ◽  
Vol 313 (3) ◽  
pp. R265-R271 ◽  
Author(s):  
Jamie K. Harrington ◽  
Robert Sorabella ◽  
Abigail Tercek ◽  
Joseph R. Isler ◽  
Kimara L. Targoff

Heart rate variability (HRV) has become an important clinical marker of cardiovascular health and a research measure for the study of the cardiac conduction system and its autonomic controls. While the zebrafish ( Danio rerio) is an ideal vertebrate model for understanding heart development, HRV has only recently been investigated in this system. We have previously demonstrated that nkx2.5 and nkx2.7, two homologues of Nkx2–5 expressed in zebrafish cardiomyocytes, play vital roles in maintaining cardiac chamber-specific characteristics. Given observed defects in ventricular and atrial chamber identities in nkx2.5−/− embryos coupled with conduction system abnormalities in murine models of Nkx2.5 insufficiency, we postulated that reduced HRV would serve as a marker of poor cardiac health in nkx2.5 mutants and in other zebrafish models of human congenital heart disease. Using live video image acquisition, we derived beat-to-beat intervals to compare HRV in wild-type and nkx2.5−/− embryos. Our data illustrate that the nkx2.5 loss-of-function model exhibits increased heart rate and decreased HRV when compared with wild type during embryogenesis. These findings validate HRV analysis as a useful quantitative tool for assessment of cardiac health in zebrafish and underscore the importance of nkx2.5 in maintaining normal heart rate and HRV during early conduction system development.


Author(s):  
T. Smuc ◽  
I. Maric ◽  
G. Bosanac ◽  
D. Gamberger ◽  
N. Bogunovic ◽  
...  

Med Phoenix ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 34-37
Author(s):  
Akhilesh Kumar Jha ◽  
Bikranta Rimal ◽  
Tarannum Khatun

Background: Ultrasonography is the reliable and safe way for the evaluation of pregnancy. Heart rate can be detected more confidently from the Ultrasonography. Heart rate is an important parameter for the evaluation of early pregnancy. The purpose of this study was to evaluate the normal heart rate in embryos/fetuses between 6 and 8 weeks of gestation.Method: In our region people are poor and most of them do not know the benefit of regular follow up examination during pregnancy. So most of pregnant women come to our centre at late stage of pregnancy. The number of pregnancy cases is good in our centre but the number of early pregnancy cases coming to regular follow up examination is low. Thus the study was conducted in 51 normal singleton pregnancies undergoing routine ultrasound examination during the first trimester of pregnancy. The duration of study was 6 weeks.Result: Out of 51 singleton pregnancies, 20 cases (39.2%) heart rate were between 131-150 beat per minute and 25 cases (49.0 %) heart rate were between 151-170 beat per minute. However 4 cases (7.8%) were between 110-120 beat per minute and 2 cases (3.9%) were more than 171 beat per minute. There were zero cases above the 180 beat per minute.Conclusion: The result of this study will help to evaluate abnormal and normal fetal heart rate so that early clinical decision whether to continue the pregnancy or terminate it can be taken, as Ultrasonography is only the method used in screening fetal well being in most of the region of our country.Med Phoenix Vol.2(1) July 2017, 34-37


2006 ◽  
Vol 50 (5) ◽  
pp. 542-548 ◽  
Author(s):  
C.-J. Huang ◽  
C.-H. Kuok ◽  
T. B. J. Kuo ◽  
Y.-W. Hsu ◽  
P.-S. Tsai

2006 ◽  
Vol 16 (3) ◽  
pp. 363-366 ◽  
Author(s):  
Yoshihiro Fujiwara ◽  
Mitsuru Hirokawa ◽  
Yoshiko Wakao ◽  
Hiroshi Itou ◽  
Toru Komatsu

2020 ◽  
pp. 1-3
Author(s):  
Aslak Widerøe Kristoffersen ◽  
Per Kristian Knudsen ◽  
Thomas Møller

Abstract A four- and a half-month-old girl with severe dilated cardiomyopathy due to neonatal enterovirus myocarditis, treated with diuretics and milrinone for the past 4 months, was infected with SARS-CoV-2. The disease course was characterised by high fever and gastrointestinal symptoms. Cardiac function, as measured by echocardiography, remained stable. The treatment focused on maintaining a normal heart rate and a stable fluid balance. In children with severe underlying cardiac disease, even a mild SARS-CoV-2 infection can require close monitoring and compound treatment.


1990 ◽  
Vol 72 (6) ◽  
pp. 1102-1102 ◽  
Author(s):  
DANIEL W. WINGARD

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