scholarly journals Analysis of the fast scanning method for tumor ablation with the effect of the large blood vessel by numerical simulation

2012 ◽  
Author(s):  
Shan Qiao ◽  
Guofeng Shen ◽  
Jingfeng Bai ◽  
Yazhu Chen
2012 ◽  
Vol 591-593 ◽  
pp. 1734-1738
Author(s):  
Chun Yan Huang ◽  
Fan Jiang

In order to study the influence of pulsating blood flow to robot and blood vessel, UDF programming of the inlet velocity is defined as the boundary condition, and the model simulate the turbulent blood flow. Moreover, in this situation, this paper analyzes the influence caused by blood parameters for the biggest surface pressure on robot. The results are showed that the variation of pressure and velocity is different on different position at 0.08s and 0.27s, and the surface pressure of the robot become greater by the increase of blood density or viscosity.


2019 ◽  
Vol 37 (2) ◽  
pp. 647-653
Author(s):  
Abbas O El-Karib ◽  
Mohammad Dallak ◽  
Mohamed Abd-Ellatif ◽  
Refaat A Eid ◽  
Mohamed A Haidara ◽  
...  

2018 ◽  
Vol 11 (06) ◽  
pp. 1850082
Author(s):  
Subrata Mukhopadhyay ◽  
Mani Shankar Mandal ◽  
Swati Mukhopadhyay

Pulsatile flow of blood in a blood vessel having time-dependent shape (diameter) is investigated numerically in order to understand some important physiological phenomena in arteries. A smooth axi-symmetric cosine shaped constriction is considered. To mimic the realistic situation as far as possible, viscosity of blood is taken to be non-uniform, a shear-thinning viscosity model is considered and a physiologically relevant pulsatile flow is introduced. Taking advantage of axi-symmetry in the proposed problem, the stream function–vorticity formulation is used to solve the governing equations for blood flow. Effect of different parameters associated with the problem on the flow pattern has been investigated and disparities from the Newtonian case are discussed in detail.


1996 ◽  
Vol 184 (3) ◽  
pp. 821-829 ◽  
Author(s):  
M Vora ◽  
L I Romero ◽  
M A Karasek

In vitro, expression of E-selectin is largely restricted to endothelial cells activated by inflammatory cytokines. Under activated conditions, cytokines such as interleukin (IL) 10, released by keratinocytes in large quantities, may also increase the expression of E-selectin on the dermal microvasculature. The aim of the present study was to investigate the expression of E-selectin on cultured human dermal microvascular endothelial cells (HDMEC) isolated from neonatal foreskins when exposed to IL-10. Expression of E-selectin was determined by immunofluorescence microscopy, FACS analysis, an HL-60 cell-binding assay, and quantitative polymerase chain reaction (PCR) analysis. For comparison with large blood vessel cells, the expression of E-selectin on human umbilical vein endothelial cells (HUVEC) was also determined in parallel by FACS and reverse transcriptase-PCR analysis under identical conditions. These studies demonstrate that IL-10 induces the expression of E-selectin on both HDMEC and HUVEC and that the level of expression of HDMEC is comparable with that induced by IL-1 beta and tumor necrosis factor-alpha. When HL-60 cells are incubated with HDMEC pretreated with IL-10, a consistent increase in adherence of HL-60 to endothelial cells is observed. This adherence was found to be mediated by L-selectin. PCR analysis and the quantification of E-selectin cDNA by a novel, highly sensitive and specific PCR-immunoassay demonstrate the induction of E-selectin mRNA at the transcriptional level. The induction of the expression of E-selectin by IL-10 on HDMEC may provide additional insights into the pathogenic mechanism of neutrophil accumulation at the site of inflammation in inflammatory skin diseases.


2013 ◽  
Vol 444-445 ◽  
pp. 1177-1181
Author(s):  
Fei Zhai ◽  
Qun Nan ◽  
Hui Juan Zhang ◽  
Xue Mei Guo

Purpose: The aim of this study is to contrast the coupling algorithm (CEE) and boundary heat exchange coefficients (Nu) used in treatment of the large blood vessel in thermal ablation. Methods: Based on the Pennes bioheat transfer equation, the models with blood vessel parallel to microwave antenna were built with finite element method. In two kind of simulation, blood flow rate was set in 0.2 m/s or boundary heat exchange coefficients was set in 1750 W / (m2 °C), respectively. Results and conclusions : There was no significant difference on shape of effective ablation areas and 54°C temperature contours by using two kinds of simulation methods, especially the place far away from the blood vessel. At the place near the blood vessel, the method of CEE is closer to real condition which considers directivity of blood. Whats more, there are higher temperature by using method of Nu inside effective ablation areas.


2011 ◽  
Author(s):  
N. Kosturski ◽  
S. Margenov ◽  
Y. Vutov ◽  
Michail D. Todorov ◽  
Christo I. Christov

2015 ◽  
Vol 208 ◽  
pp. S25
Author(s):  
Tiganescu Tudor Viorel ◽  
Costache Victor ◽  
Matache Liviu ◽  
Trana Eugen ◽  
Ciobanu Emanuela ◽  
...  

1995 ◽  
Vol 40 (4) ◽  
pp. 477-494 ◽  
Author(s):  
M C Kolios ◽  
M D Sherar ◽  
J W Hunt

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