A multi-view time-domain non-contact diffuse optical tomography scanner with dual wavelength detection for intrinsic and fluorescence small animal imaging

2012 ◽  
Vol 83 (6) ◽  
pp. 063703 ◽  
Author(s):  
Eric Lapointe ◽  
Julien Pichette ◽  
Yves Bérubé-Lauzière
Keyword(s):  
Time Domain ◽  
Optical Tomography ◽  
Small Animal Imaging ◽  
Diffuse Optical Tomography ◽  
Small Animal ◽  
Dual Wavelength ◽  
Animal Imaging ◽  
Wavelength Detection

scholarly journals Ultrafast contour imaging for time-domain diffuse optical tomography

2020 ◽  
Author(s):  
Xiaohua Feng ◽  
Liang Gao
Keyword(s):  
Time Domain ◽  
Collection Efficiency ◽  
Signal To Noise Ratio ◽  
Optical Tomography ◽  
Small Animal Imaging ◽  
Diffuse Optical Tomography ◽  
Small Animal ◽  
Depth Of Field ◽  
Light Collection ◽  
Imaging Results

Diffuse optical tomography (DOT) is well known to be ill-posed and suffers from a poor resolution. While time domain DOT can bolster the resolution by time-gating to extract weakly scattering photons, it is often confronted by an inferior signal to noise ratio and a low measurement density. This is particularly problematic for non-contact DOT imaging of non-planar objects, which faces an inherent tradeoff between the light collection efficiency and depth of field. We present here ultrafast contour imaging, a method that enables efficient light collection over curved surfaces with a dense spatiotemporal sampling of diffused light, allowing DOT imaging in the object’s native geometry with an improved resolution. We demonstrated our approach with both phantom and small animal imaging results. ©2020 Optical Society of America

scholarly journals Simultaneous in vivo dynamic magnetic resonance-diffuse optical tomography for small animal imaging

2008 ◽  
Vol 13 (6) ◽  
pp. 060501 ◽  
Author(s):  
Mehmet Burcin Unlu ◽  
Yuting Lin ◽  
Ozlem Birgul ◽  
Orhan Nalcioglu ◽  
Gultekin Gulsen
Keyword(s):  
Magnetic Resonance ◽  
Optical Tomography ◽  
Small Animal Imaging ◽  
Diffuse Optical Tomography ◽  
Small Animal ◽  
Dynamic Magnetic Resonance ◽  
Animal Imaging

scholarly journals Volumetric Diffuse Optical Tomography for Small Animals Using a CCD-Camera-Based Imaging System

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Zi-Jing Lin ◽  
Haijing Niu ◽  
Lin Li ◽  
Hanli Liu
Keyword(s):  
Imaging System ◽  
Optical Tomography ◽  
Small Animal Imaging ◽  
Three Dimensional ◽  
Diffuse Optical Tomography ◽  
Small Animal ◽  
Ccd Camera ◽  
Animal Imaging ◽  
Volumetric Images ◽  
Phantom Studies

We report the feasibility of three-dimensional (3D) volumetric diffuse optical tomography for small animal imaging by using a CCD-camera-based imaging system with a newly developed depth compensation algorithm (DCA). Our computer simulations and laboratory phantom studies have demonstrated that the combination of a CCD camera and DCA can significantly improve the accuracy in depth localization and lead to reconstruction of 3D volumetric images. This approach may present great interests for noninvasive 3D localization of an anomaly hidden in tissue, such as a tumor or a stroke lesion, for preclinical small animal models.

scholarly journals Multi-modal molecular diffuse optical tomography system for small animal imaging

2013 ◽  
Vol 24 (10) ◽  
pp. 105405 ◽  
Author(s):  
James A Guggenheim ◽  
Hector R A Basevi ◽  
Jon Frampton ◽  
Iain B Styles ◽  
Hamid Dehghani
Keyword(s):  
Optical Tomography ◽  
Small Animal Imaging ◽  
Diffuse Optical Tomography ◽  
Small Animal ◽  
Tomography System ◽  
Animal Imaging

scholarly journals Numerical simulation of x-ray luminescence optical tomography for small-animal imaging

2014 ◽  
Vol 19 (4) ◽  
pp. 046002 ◽  
Author(s):  
Changqing Li ◽  
Arnulfo Martínez-Dávalos ◽  
Simon R. Cherry
Keyword(s):  
Numerical Simulation ◽  
Optical Tomography ◽  
Small Animal Imaging ◽  
Small Animal ◽  
X Ray ◽  
Animal Imaging

MRI guided Fluorescence Optical Tomography for Small Animal Imaging

2004 ◽  
Author(s):  
Anand T. N. Kumar ◽  
Jonathan J. Stott ◽  
Q uan Zhang ◽  
Young Ro Kim ◽  
David A. Boas ◽  
...  
Keyword(s):  
Optical Tomography ◽  
Small Animal Imaging ◽  
Small Animal ◽  
Animal Imaging ◽  
Mri Guided
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