Monitoring iron oxide nanoparticle surface temperature in an alternating magnetic field using thermoresponsive fluorescent polymers

2012 ◽  
Vol 111 (7) ◽  
pp. 07B334 ◽  
Author(s):  
Liliana Polo-Corrales ◽  
Carlos Rinaldi
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Surface Temperature ◽  
Alternating Magnetic Field ◽  
Iron Oxide Nanoparticle ◽  
Nanoparticle Surface ◽  
Fluorescent Polymers ◽  
Oxide Nanoparticle

Alternating magnetic field plate for enhanced magnetofection of iron oxide nanoparticle conjugated nucleic acids

2019 ◽  
Vol 469 ◽  
pp. 598-605 ◽  
Author(s):  
Murat Kaya Yapici ◽  
Ahmad Al Nabulsi ◽  
Nahla Rizk ◽  
Selwa Mokhtar Boularaoui ◽  
Nicolas Christoforou ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Nucleic Acids ◽  
Alternating Magnetic Field ◽  
Iron Oxide Nanoparticle ◽  
Field Plate ◽  
Oxide Nanoparticle

Synthesis of spinel iron oxide nanoparticle/organic hybrid for hyperthermia

2008 ◽  
Vol 23 (12) ◽  
pp. 3415-3424 ◽  
Author(s):  
Koichiro Hayashi ◽  
Toshifumi Shimizu ◽  
Hidefumi Asano ◽  
Wataru Sakamoto ◽  
Toshinobu Yogo
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Photoelectron Spectroscopy ◽  
Iron Oxide Nanoparticle ◽  
Organic Hybrid ◽  
Oxide Nanoparticle ◽  
Hydrolysis Conditions ◽  
Size Controlled ◽  
Controlled Hydrolysis

Size-controlled spinel iron oxide (SIO) nanoparticle/organic hybrid was synthesized in situ from iron (III) allylacetylacetonate (IAA) at around 80 °C. The formation of SIO particles chemically bound with organics was confirmed by infrared and x-ray photoelectron spectroscopy. The sizes of SIO nanoparticles in the hybrids were monodispersed and ranged from 7 to 23 nm under controlled hydrolysis conditions. The hybrid including SIO particles of 7.3 nm was superparamagnetic, whereas those dispersed with particles above 11 nm were ferrimagnetic. The specific absorption rate (SAR) value was dependent upon the magnetic properties of the hybrid at 100 Oe. The SAR was 15.2 W g−1 in a 230 kHz alternating magnetic field and 100 Oe when the crystallite size of SIO particle in the hybrid was 16 nm. The temperatures of agars dispersed with hybrid powders of 5 and 8 mg ml−1 reached the optimum temperature (42 °C) for 17 and 8 min, respectively. The increase in temperature was controlled in terms of the strength of magnetic field. The simulation of heat transfer in the agar phantom model revealed that the suitable temperature distribution for therapy was attained from 15 to 20 min at 230 kHz and 100 Oe.

scholarly journals Targeted Delivery of Iron Oxide Nanoparticle-Loaded Human Embryonic Stem Cell-Derived Spherical Neural Masses for Treating Intracerebral Hemorrhage

2020 ◽  
Vol 21 (10) ◽  
pp. 3658
Author(s):  
Min Kyoung Kang ◽  
Tae Jung Kim ◽  
Young-Ju Kim ◽  
Lamie Kang ◽  
Jonghoon Kim ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Stem Cells ◽  
Stem Cell ◽  
Iron Oxide ◽  
External Magnetic Field ◽  
Targeted Delivery ◽  
Human Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Iron Oxide Nanoparticle ◽  
Oxide Nanoparticle

This study evaluated the potential of iron oxide nanoparticle-loaded human embryonic stem cell (ESC)-derived spherical neural masses (SNMs) to improve the transportation of stem cells to the brain, ameliorate brain damage from intracerebral hemorrhage (ICH), and recover the functional status after ICH under an external magnetic field of a magnet attached to a helmet. At 24 h after induction of ICH, rats were randomly separated into three experimental groups: ICH with injection of phosphate-buffered saline (PBS group), ICH with intravenous injection of magnetosome-like ferrimagnetic iron oxide nanocubes (FION)-labeled SNMs (SNMs* group), and ICH with intravenous injection of FION-labeled SNMs followed by three days of external magnetic field exposure for targeted delivery by a magnet-embedded helmet (SNMs*+Helmet group). On day 3 after ICH induction, an increased Prussian blue-stained area and decreased swelling volume were observed in the SNMs*+Helmet group compared with that of the other groups. A significantly decreased recruitment of macrophages and neutrophils and a downregulation of pro-inflammatory cytokines followed by improved neurological function three days after ICH were observed in the SNMs*+Helmet group. Hemispheric atrophy at six weeks after ICH was significantly decreased in the SNMs*+Helmet group compared with that of the PBS group. In conclusion, we have developed a targeted delivery system using FION tagged to stem cells and a magnet-embedded helmet. The targeted delivery of SNMs might have the potential for developing novel therapeutic strategies for ICH.

Observing the colloidal stability of iron oxide nanoparticlesin situ

Nanoscale ◽  
2019 ◽  
Vol 11 (27) ◽  
pp. 13098-13107 ◽  
Author(s):  
Ryan Hufschmid ◽  
Eric Teeman ◽  
B. Layla Mehdi ◽  
Kannan M. Krishnan ◽  
Nigel D. Browning
Keyword(s):  
Iron Oxide ◽  
Scanning Transmission Electron Microscopy ◽  
Colloidal Stability ◽  
Iron Oxide Nanoparticle ◽  
Nanoparticle Surface ◽  
Transmission Electron ◽  
Scanning Transmission ◽  
Liquid Cell ◽  
Oxide Nanoparticle

Iron oxide nanoparticle surface chemistry controls growth and dissolution, which are observed in real-time usingin situliquid cell Scanning Transmission Electron Microscopy (STEM).

scholarly journals Effects of Iron-Oxide Nanoparticle Surface Chemistry on Uptake Kinetics and Cytotoxicity in CHO-K1 Cells

2015 ◽  
Vol 17 (1) ◽  
pp. 54 ◽  
Author(s):  
Camille Hanot ◽  
Young Choi ◽  
Tareq Anani ◽  
Dharsan Soundarrajan ◽  
Allan David
Keyword(s):  
Iron Oxide ◽  
Surface Chemistry ◽  
Uptake Kinetics ◽  
Iron Oxide Nanoparticle ◽  
Nanoparticle Surface ◽  
Oxide Nanoparticle
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